AXSMAXSMHealthcare · Biotechnology

AXSM Stock Forecast: Axsome Therapeutics, Inc. Price Predictions for 2026-2027

Last close, 14 Aug 2026
$214
−0.00% on the day

The 21 Wall Street analysts covering Axsome Therapeutics, Inc. hold a median 12-month price target of $280 — +31.0% from the last close. Ticker Nerd's systematic factor model, run across ~4,600 US stocks, ranks it 73 of 100 as at 15 Aug 2026 — in the upper half. Here, the model and the Street point the same way.

Market cap
$11.2B
Ticker Nerd rank
73 / 100
Median analyst target
$280
Analysts covering
21
Total return, dividends reinvested
1W
+0.4%
1M
−9.2%
YTD
+17.0%
1Y
+96.5%
From 52W high
−16.3%
From 52W low
+96.5%
$109
$255
52-week range, adjusted closes · the dot is the last close
Ticker Nerd rank

AXSM stock analysis: one number for the whole business

Consensus tells you what everyone already believes. The model scores Axsome Therapeutics, Inc. on its factor families — the same systematic rank behind the Ticker Nerd portfolio.

Where the model ranks itAs at 15 Aug 2026
73 / 100

Percentile across ~4,600 US stocks on Ticker Nerd’s systematic factor model. Higher is better. How the model is built and tested

Volatility
93
Quality
92
Value
91
Momentum
85
Accruals
63
Growth
60
Issuance
39
Revisions
37
Size
15

Volatility (93): The share price has been relatively steady.

Revisions (37): Analysts have, on balance, been cutting their forecasts.

Size (15): Larger than most of the companies we track — more scrutinised, less often mispriced.

Built and run by Aslam Ghouse, an ex-Goldman Sachs quant trader with fourteen years in markets.

Wall Street

AXSM stock forecast 2026-2027: analyst price targets & predictions

The bullish and bearish analyst opinions on AXSM, reported as data — targets and ratings, the market's view beside the model's.

Share price and the analyst range, 12 monthsAdjusted close, US dollars
$50$100$150$200$250$300$350$400Oct 25Jan 26Apr 26Jul 26AXSMHigh $380Median $280Low $246

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

What Wall Street says21 analysts
20 Buy1 Hold0 Sell
Low $246Median $280High $380

The green dot is the last close — the median target sits +31.0% from it.

Recent analyst actionsNewest first

Of the 20 most recent actions, 5 moved their price target up and 2 moved it down.

DateFirmActionRatingTarget
12 Aug 2026MizuhoMaintainsOutperform$306$316
11 Aug 2026GuggenheimMaintainsBuy$260$275
11 Aug 2026Morgan StanleyMaintainsEqual-Weight$242$251
11 Aug 2026NeedhamMaintainsBuy$267$268
11 Aug 2026RBC CapitalMaintainsOutperform$304$297
11 Aug 2026Wells FargoMaintainsOverweight$255$256
31 July 2026MizuhoMaintainsOutperform$310$306
31 July 2026MizuhoMaintainsOutperform
21 July 2026BMO CapitalInitiatesOutperform$310
21 July 2026BMO CapitalInitiatesOutperform
15 July 2026HC Wainwright & Co.ReiteratesBuy$290
15 July 2026HC Wainwright & Co.ReiteratesBuy
8 July 2026HC Wainwright & Co.ReiteratesBuy$290
8 July 2026HC Wainwright & Co.ReiteratesBuy
7 July 2026RBC CapitalMaintainsOutperform
17 June 2026TD CowenMaintainsBuy
5 May 2026BairdMaintainsOutperform
5 May 2026GuggenheimMaintainsBuy
5 May 2026HC Wainwright & Co.MaintainsBuy
5 May 2026MizuhoMaintainsOutperform

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Market Radar

This page is one stock. Monday covers all of them.

Computed off the Friday close and sent before the US open.

Market Radar reports the week’s largest rank changes across roughly 4,600 US stocks, the factor behind each one, and where the market went. AXSM appears on the weeks it earns a place.

Free, every Monday. Unsubscribe any time.

Estimates

AXSM analyst estimate revisions

Not the forecast itself — the direction analysts are revising it. Revision direction is one of the model's factor families.

Which way the estimates are movingNext fiscal year
Analysts raising
1
Analysts cutting
0
Fundamentals

Axsome Therapeutics, Inc. (AXSM) financial data

A margin means little on its own. Each bar marks where the figure sits across the whole US universe we score.

Valuation
Trailing P/E
−58.1×

Cheaper than 98% of US stocks

Price / sales
14.4×

Cheaper than 12% of US stocks

Price / book
134.1×

Cheaper than 1% of US stocks

EV / EBITDA
−64.2×

Cheaper than 95% of US stocks

Growth & margins
Revenue growth (YoY)
45.5%

Higher than 85% of US stocks

Earnings growth (YoY)
57.4%

Higher than 77% of US stocks

Gross margin
92.3%

Higher than 97% of US stocks

Operating margin
−23.4%

Higher than 21% of US stocks

Net margin
−24.7%

Higher than 14% of US stocks

Returns & dividend
Return on equity
−245.1%

Higher than 6% of US stocks

Return on assets
−16.3%

Higher than 22% of US stocks

Dividend yield

Bars mark the percentile across the ~4,600 US stocks Ticker Nerd covers, among those reporting the figure.

Peers

AXSM vs competitors

The nearest names by industry and size, scored by the same model — like for like.

Its peer group, ranked by the same modelBiotechnology
CompanyMarket capTKN rank
AXSMAxsome Therapeutics, Inc.$11.2B
73
HALOHalozyme Therapeutics, Inc.$11.2B
96
TECHBio-Techne Corp.$11.3B
94
SMMTSummit Therapeutics, Inc.$10.6B
19
MDGLMadrigal Pharmaceuticals, Inc.$11.6B
69
CYTKCytokinetics, Inc.$10.3B
49
APGEApogee Therapeutics, Inc.$10.1B
36

Look up any of the roughly 4,600 stocks we score.

The rank is the raw material. Whether the rules would actually own Axsome Therapeutics, Inc. — and when they’d sell — is the membership. See the Ticker Nerd 20 →

News

Latest AXSM news & analysis

Axsome's Q2 Earnings Meet Estimates, Auvelity Drives Y/Y Revenues

Zacks Investment Research · 11 Aug 2026neutral

Axsome reported Q2 earnings that met estimates, although revenues missed forecasts. Sales of Auvelity and other products drove year-over-year revenue growth.

Why it matters — AXSM watchers would follow whether Auvelity and other product sales continue to support revenue growth against mixed quarterly results.

Axsome Therapeutics Q2 Earnings Review: I Just Can't See The Value Proposition

Seeking Alpha · 11 Aug 2026negative

Axsome Therapeutics reported 46% year-on-year net product revenue growth in Q2 2026, led by Auvelity, but rising SG&A costs offset commercial gains and profitability remains out of reach.

Why it matters — A watcher would care because the company's path to profitability remains uncertain even as Auvelity's revenue grows, and management's ambitious peak sales target faces mounting skepticism.

Axsome Therapeutics Analysts Increase Their Forecasts Following Q2 Results

Benzinga · 11 Aug 2026positive

Axsome Therapeutics posted downbeat results for the second quarter. Following these results, analysts increased their forecasts for the company.

Why it matters — AXSM watchers would care because analyst forecast increases after the earnings report signal revised expectations for the company's outlook.

Axsome Therapeutics, Inc. (AXSM) Q2 2026 Earnings Call Transcript

Seeking Alpha · 10 Aug 2026neutral

Axsome Therapeutics held its Q2 2026 earnings call, and a transcript of the call was published by Seeking Alpha. The excerpt provides only the headline and source, with no financial details or commentary included.

Why it matters — A transcript of the Q2 2026 earnings call offers investors access to management's discussion of the company's recent performance and outlook.

Axsome (AXSM) Reports Q2 Earnings: What Key Metrics Have to Say

Zacks Investment Research · 10 Aug 2026neutral

Axsome Therapeutics reported its Q2 2026 financial results, with the article noting that key metrics can be compared to Wall Street estimates and year-ago figures.

Why it matters — The comparison of Axsome's key metrics to analyst estimates and prior-year figures provides investors with a framework for assessing the company's quarterly performance.

FAQ

Frequently asked questions about AXSM stock

What is the AXSM stock price forecast for 2026-2027?

The 21 Wall Street analysts covering Axsome Therapeutics, Inc. have a median 12-month price target of $280, with estimates ranging from $246 to $380. These are third-party analyst estimates, not Ticker Nerd forecasts, and they are frequently wrong.

Is AXSM stock a buy right now?

Of the 21 analysts covering Axsome Therapeutics, Inc., 20 rate it a Buy, 1 a Hold and 0 a Sell. Ticker Nerd's systematic factor model ranks Axsome Therapeutics, Inc. 73 out of 100 across roughly 4,600 US stocks as at 15 Aug 2026. None of this is personal advice — it does not consider your circumstances.

How does Ticker Nerd's model rank AXSM?

As at 15 Aug 2026, Axsome Therapeutics, Inc. ranks 73 out of 100 on Ticker Nerd's systematic factor model — a percentile across roughly 4,600 US stocks, built from its factor families. Its strongest factor family is Volatility (93 of 100).

Will AXSM stock go up?

No one can know that. What the data says: the median 12-month target from 21 analysts implies +31.0% from the last close, and Ticker Nerd's factor model ranks Axsome Therapeutics, Inc. 73 out of 100 as at 15 Aug 2026. Analyst targets are third-party estimates and frequently wrong; none of this is personal advice.

What is the AXSM stock forecast for 2030?

No analyst covering Axsome Therapeutics, Inc. publishes a 2030 price target — Wall Street targets run 12 to 18 months out. Sites quoting a 2030 price for AXSM are extrapolating price history, which says nothing about the business. The furthest attributed numbers are the current analyst targets: $246 to $380 over the next 12 months.

How has AXSM stock performed over the past year?

Axsome Therapeutics, Inc. returned +96.5% over the 12 months to 14 Aug 2026, with dividends reinvested. Past performance does not indicate future returns.

What does Axsome Therapeutics, Inc. do?

Axsome Therapeutics, Inc. is a commercial-stage biopharmaceutical company focused on developing and marketing therapies for central nervous system conditions with limited treatment options.

What is the latest news on AXSM?

The most recent item we track (Zacks Investment Research, 11 Aug 2026): "Axsome's Q2 Earnings Meet Estimates, Auvelity Drives Y/Y Revenues". Axsome reported Q2 earnings that met estimates, although revenues missed forecasts. Sales of Auvelity and other products drove year-over-year revenue growth.

Company

About Axsome Therapeutics, Inc.

Axsome Therapeutics, Inc. is a commercial-stage biopharmaceutical company focused on developing and marketing therapies for central nervous system conditions with limited treatment options. Headquartered in New York City and founded in 2012, the company concentrates on neuropsychiatric and neurological disorders such as major depressive disorder, excessive daytime sleepiness associated with narcolepsy or obstructive sleep apnea, Alzheimer’s disease agitation, migraine, narcolepsy, and fibromyalgia. Axsome Therapeutics currently markets branded prescription CNS medicines, including Auvelity for major depressive disorder and Sunosi for excessive daytime sleepiness, distributed through pharmaceutical channels to adult patients under physician prescription. In parallel, it maintains a late-stage and clinical pipeline featuring differentiated small-molecule candidates like AXS-05, AXS-12, and AXS-14 targeting additional CNS indications. Operating as a single business segment, Axsome Therapeutics plays a specialized role in the healthcare market by addressing high unmet need in adult CNS disorders and supplying neurologists, psychiatrists, sleep specialists, and primary care physicians with novel therapeutic options.

CEO Dr. Herriot Tabuteau M.D. · 1,346 employees · United States · https://www.axsome.com