AXSMAXSMHealthcare · Biotechnology

AXSM Stock Forecast: Axsome Therapeutics, Inc. Price Predictions for 2026-2027

Last close, 4 Nov 2026
$137
−1.91% on the day

The 22 Wall Street analysts covering Axsome Therapeutics, Inc. hold a median 12-month price target of $275 — +100.8% from the last close. Ticker Nerd's systematic factor model, run across ~4,600 US stocks, ranks it 68 of 100 as at 3 Nov 2026 — in the upper half.

Market cap
$7.1B
Ticker Nerd rank
68/ 100
Median analyst target
$275
Analysts covering
22
Revenue$218.4M+45.5% y/y
Operating income−$51.1M
Net income−$51.3M
Free cash flow−$33.4M
Quarterly, 8 quarters to 30 June 2026 · latest quarter's figure shown
Total return, dividends reinvested
1W
−4.6%
1M
−23.6%
YTD
−25.0%
1Y
+1.5%
From 52W high
−46.3%
From 52W low
+1.5%
$135
$255
52-week range, adjusted closes · the dot is the last close
Ticker Nerd rank

AXSM stock analysis: one number for the whole business

Consensus tells you what everyone already believes. The model scores Axsome Therapeutics, Inc. on its factor families — the same systematic rank behind the Ticker Nerd portfolio.

Where the model ranks itAs at 3 Nov 2026
68/ 100

Percentile across ~4,600 US stocks on Ticker Nerd’s systematic factor model. Higher is better. How the model is built and tested

Quality
94
Volatility
94
Value
91
Growth
66
Momentum
65
Accruals
46
Revisions
44
Issuance
35
Size
18

Quality (94): The business earns solid, repeatable profits on what it owns.

Issuance (35): The company has been issuing shares or taking on financing, diluting existing holders.

Size (18): Larger than most of the companies we track — more scrutinised, less often mispriced.

Built and run by Aslam Ghouse, an ex-Goldman Sachs systematic trader with 15+ years in markets.

Wall Street

AXSM stock forecast 2026-2027: analyst price targets & predictions

The bullish and bearish analyst opinions on AXSM, reported as data — targets and ratings, the market's view beside the model's.

Share price and the analyst range, 12 monthsAdjusted close, US dollars
$150$200$250$300$350$400Jan 26Apr 26Jul 26Oct 26AXSMHigh $380Median $275Low $238

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Data provided by Twelve Data

What Wall Street says22 analysts
21 Buy1 Hold0 Sell
Low $238Median $275High $380

The green dot is the last close — the median target sits +100.8% from it.

Recent analyst actionsNewest first

Of the 20 most recent actions, 3 moved their price target up and 8 moved it down.

DateFirmActionRatingTarget
3 Nov 2026BairdMaintainsOutperform$246 → $220
3 Nov 2026GuggenheimMaintainsBuy$275 → $250
3 Nov 2026Morgan StanleyMaintainsEqual-Weight$247 → $249
3 Nov 2026RBC CapitalMaintainsOutperform$295 → $273
3 Nov 2026UBSMaintainsBuy$256 → $239
26 Oct 2026Piper SandlerMaintainsOverweight$258 → $238
8 Oct 2026RBC CapitalMaintainsOutperform$297 → $295
8 Oct 2026RBC CapitalMaintainsOutperform—
29 Sept 2026Deutsche BankMaintainsBuy—
29 Sept 2026Deutsche BankMaintainsBuy$280 → $267
25 Sept 2026Morgan StanleyMaintainsEqual-Weight—
25 Sept 2026Morgan StanleyMaintainsEqual-Weight$251 → $247
23 Sept 2026Truist SecuritiesMaintainsBuy$200 → $285
23 Sept 2026Truist SecuritiesMaintainsBuy—
18 Sept 2026Piper SandlerReiteratesOverweight$258
18 Sept 2026Piper SandlerReiteratesOverweight—
31 Aug 2026HC Wainwright & Co.ReiteratesBuy$290
31 Aug 2026HC Wainwright & Co.ReiteratesBuy—
12 Aug 2026MizuhoMaintainsOutperform$306 → $316
12 Aug 2026MizuhoMaintainsOutperform—

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Market Radar

This page is one stock. Monday covers all of them.

AXSM appears in the Radar on the weeks it earns a place.

  • Market Radar, every Monday: the week's biggest rank moves across ~4,600 US stocks, and the reason for each.
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Performance

AXSM vs the S&P 500

Both lines are total return — dividends reinvested — so the comparison is honest on both sides.

Over the twelve months to 4 Nov 2026, Axsome Therapeutics, Inc. returned +1.5% against +14.8% for the S&P 500, dividends included.

AXSM vs S&P 500, last 12 monthsTotal return, rebased to 100
100120140160180200Jan 26Apr 26Jul 26Oct 26AXSMS&P 500

Download this chart as an image — free to reuse; link this page as the source.

Data provided by Twelve Data

Estimates

AXSM analyst estimate revisions

Not the forecast itself — the direction analysts are revising it. Revision direction is one of the model's factor families.

Which way the estimates are movingThis fiscal year
Analysts raising
0
Analysts cutting
2
Fundamentals

Axsome Therapeutics, Inc. (AXSM) financial data

A margin means little on its own. Each bar marks where the figure sits across the whole US universe we score.

Valuation
Trailing P/E
−38.3×

Cheaper than 98% of US stocks

Price / sales
8.6×

Cheaper than 15% of US stocks

Price / book
70.5×

Cheaper than 2% of US stocks

EV / EBITDA
−46.3×

Cheaper than 94% of US stocks

Growth & margins
Revenue growth (YoY)
51.9%

Higher than 86% of US stocks

Earnings growth (YoY)
45.5%

Higher than 73% of US stocks

Gross margin
93.8%

Higher than 98% of US stocks

Operating margin
−5.2%

Higher than 27% of US stocks

Net margin
−18.2%

Higher than 16% of US stocks

Returns & dividend
Return on equity
−175.6%

Higher than 8% of US stocks

Return on assets
−13.7%

Higher than 24% of US stocks

Dividend yield
0.0%

Higher than 1% of US dividend payers

Bars mark the percentile across the ~4,600 US stocks Ticker Nerd covers, among those reporting the figure.

Key statistics

Axsome Therapeutics, Inc. (AXSM) statistics: revenue, profit & scale

The headline figures, each with its date. Every row carries its own link — cite it straight from here.

  • Axsome Therapeutics, Inc. has a market value of $7.1B and an enterprise value of $7.1B.

  • Revenue in the twelve months to 30 June 2026: $776.6M. The latest quarter grew 51.9% year on year.

  • Net income over the same four quarters: −$191.6M, a −24.7% net margin.

  • Diluted earnings per share, trailing twelve months: $−3.75.

  • Free cash flow in the twelve months to 30 June 2026: −$72.0M.

  • Shares outstanding: 52.3M.

  • Trailing P/E: −38.3×; forward P/E: 34.6× — the forward figure prices analyst consensus estimates, not reported earnings.

  • Forward dividend yield: 0.00%, paying out 0% of earnings.

  • Axsome Therapeutics, Inc. employs 925 people — $840K of revenue per employee.

Statement figures: company filings via Twelve Data, four quarters to 30 June 2026 · market figures as at 3 Nov 2026

Data provided by Twelve Data

Peers

AXSM vs competitors

The nearest names by industry and size, scored by the same model — like for like.

Its peer group, ranked by the same modelBiotechnology
CompanyMarket capTKN rank
AXSMAxsome Therapeutics, Inc.$7.1B68
IONSIonis Pharmaceuticals, Inc.$6.7B39
PRAXPraxis Precision Medicines, Inc.$7.7B46
ORKAOruka Therapeutics, Inc.$6.6B39
ARWRArrowhead Pharmaceuticals, Inc.$8.3B54
LGNDLigand Pharmaceuticals, Inc.$6.2B65
CYTKCytokinetics, Inc.$8.7B48

Look up any of the roughly 4,600 stocks we score.

The rank is the raw material. Whether the rules would actually own Axsome Therapeutics, Inc. — and when they’d sell — is the membership. See the Ticker Nerd 20 →

News

Latest AXSM news & analysis

Axsome: 3 Key Takeaways for Long-Term Investors

The Motley Fool · 4 Nov 2026positive

The Motley Fool highlighted Axsome’s 52% year-over-year third-quarter revenue growth to $260 million and management’s expectation that Auvelity could reach $8 billion in peak annual revenue.

Why it matters — These figures and the stated Auvelity revenue expectation are relevant to investors tracking Axsome’s commercial performance and management outlook.

Axsome Therapeutics to Participate in Upcoming Investor Conferences

GlobeNewsWire · 3 Nov 2026neutral

Axsome Therapeutics announced it will participate in four investor conferences in November 2026, including fireside chats at the Guggenheim and UBS conferences and investor meetings at the Wolfe Research and Truist events.

Why it matters — The announcement provides AXSM watchers with dates and formats for upcoming opportunities to hear from or meet with the company.

Axsome Therapeutics: Sentiment Meets Reality After Q3 (Rating Upgrade)

Seeking Alpha · 2 Nov 2026negative

Seeking Alpha upgraded Axsome Therapeutics to Hold, saying its valuation better reflects commercial realities following ADA approval. The article notes slower-than-hoped AUVELITY growth in ADA scripts and says Q3’s technical beat benefited from one-time items and improved gross-to-net rather than sustainable volume growth.

Why it matters — AXSM watchers may care because the article points to slower ADA uptake and questions the durability of reported sales growth.

Axsome Therapeutics, Inc. (AXSM) Q3 2026 Earnings Call Transcript

Seeking Alpha · 2 Nov 2026neutral

Seeking Alpha published a transcript of Axsome Therapeutics, Inc.’s Q3 2026 earnings call. The provided excerpt contains only the headline and does not include details from the call.

Why it matters — AXSM watchers can note that a Q3 2026 earnings-call transcript is available, but the excerpt provides no information about the company’s reported results or commentary.

What Axsome Therapeutics (AXSM) Said on Its Q3 Earnings Call

MarketBeat · 2 Nov 2026positive

Axsome Therapeutics reported third-quarter revenue growth of 52% year over year, driven primarily by continued expansion of AUVELITY sales in major depressive disorder and Alzheimer's disease agitation.

Why it matters — AXSM watchers may note the reported revenue growth and the product sales areas identified as its primary drivers.

FAQ

Frequently asked questions about AXSM stock

What is the AXSM stock price forecast for 2026-2027?

The 22 Wall Street analysts covering Axsome Therapeutics, Inc. have a median 12-month price target of $275, with estimates ranging from $238 to $380. These are third-party analyst estimates, not Ticker Nerd forecasts, and they are frequently wrong.

Is AXSM stock a buy right now?

Of the 22 analysts covering Axsome Therapeutics, Inc., 21 rate it a Buy, 1 a Hold and 0 a Sell. Ticker Nerd's systematic factor model ranks Axsome Therapeutics, Inc. 68 out of 100 across roughly 4,600 US stocks as at 3 Nov 2026. None of this is personal advice — it does not consider your circumstances.

How does Ticker Nerd's model rank AXSM?

As at 3 Nov 2026, Axsome Therapeutics, Inc. ranks 68 out of 100 on Ticker Nerd's systematic factor model — a percentile across roughly 4,600 US stocks, built from its factor families. Its strongest factor family is Quality (94 of 100).

Will AXSM stock go up?

No one can know that. What the data says: the median 12-month target from 22 analysts implies +100.8% from the last close, and Ticker Nerd's factor model ranks Axsome Therapeutics, Inc. 68 out of 100 as at 3 Nov 2026. Analyst targets are third-party estimates and frequently wrong; none of this is personal advice.

What is the AXSM stock forecast for 2030?

No analyst covering Axsome Therapeutics, Inc. publishes a 2030 price target — Wall Street targets run 12 to 18 months out. Sites quoting a 2030 price for AXSM are extrapolating price history, which says nothing about the business. The furthest attributed numbers are the current analyst targets: $238 to $380 over the next 12 months.

How has AXSM stock performed over the past year?

Axsome Therapeutics, Inc. returned +1.5% over the 12 months to 4 Nov 2026, with dividends reinvested. Past performance does not indicate future returns.

What does Axsome Therapeutics, Inc. do?

Axsome Therapeutics Inc. is a biopharmaceutical company focused on developing and commercializing therapies for central nervous system disorders.

What is the latest news on AXSM?

The most recent item we track (The Motley Fool, 4 Nov 2026): "Axsome: 3 Key Takeaways for Long-Term Investors". The Motley Fool highlighted Axsome’s 52% year-over-year third-quarter revenue growth to $260 million and management’s expectation that Auvelity could reach $8 billion in peak annual revenue.

Company

About Axsome Therapeutics, Inc.

Axsome Therapeutics Inc. is a biopharmaceutical company focused on developing and commercializing therapies for central nervous system disorders. Its marketed products include Auvelity for major depressive disorder, Sunosi for excessive daytime sleepiness related to narcolepsy or obstructive sleep apnea, and Symbravo for the acute treatment of migraine. The company also maintains a neuroscience pipeline spanning additional neurological and psychiatric conditions, reflecting its emphasis on disorders with limited treatment options. Axsome Therapeutics Inc. plays a specialized role in the healthcare market by combining commercial products with ongoing clinical development in psychiatry, sleep medicine, pain, and migraine care. Based in New York, the company is positioned as a focused CNS innovator serving patients, physicians, and healthcare systems with therapies designed to address unmet medical needs.

CEO Dr. Herriot Tabuteau M.D. · 925 employees · United States · https://www.axsome.com