CRBUCRBUHealthcare · Biotechnology

CRBU Stock Forecast: Caribou Biosciences, Inc. Price Predictions for 2026-2027

Last close, 12 Oct 2026
$0.50
+8.02% on the day

The 6 Wall Street analysts covering Caribou Biosciences, Inc. hold a median 12-month price target of $4.5 — +805.6% from the last close. Ticker Nerd's systematic factor model, run across ~4,600 US stocks, ranks it 46 of 100 as at 12 Oct 2026 — in the lower half.

Market cap
$49.3M
Ticker Nerd rank
46 / 100
Median analyst target
$4.50
Analysts covering
6
Revenue$1.5M−43.8% y/y
Operating income−$25.3M
Net income−$24.3M
Free cash flow−$22.8M
Quarterly, 8 quarters to 30 June 2026 · latest quarter's figure shown
Total return, dividends reinvested
1W
−58.2%
1M
−60.9%
YTD
−68.7%
1Y
−80.0%
From 52W high
−82.5%
From 52W low
+8.0%
$0.46
$2.84
52-week range, adjusted closes · the dot is the last close
Ticker Nerd rank

CRBU stock analysis: one number for the whole business

Consensus tells you what everyone already believes. The model scores Caribou Biosciences, Inc. on its factor families — the same systematic rank behind the Ticker Nerd portfolio.

Where the model ranks itAs at 12 Oct 2026
46 / 100

Percentile across ~4,600 US stocks on Ticker Nerd’s systematic factor model. Higher is better. How the model is built and tested

Growth
99
Revisions
81
Size
81
Accruals
71
Issuance
26
Volatility
26
Quality
20
Momentum
17
Value
7

Growth (99): Sales and profits are climbing, and climbing faster than before.

Value (7): The shares cost a lot relative to the profits and assets behind them.

Built and run by Aslam Ghouse, an ex-Goldman Sachs quant trader with fourteen years in markets.

Wall Street

CRBU stock forecast 2026-2027: analyst price targets & predictions

The bullish and bearish analyst opinions on CRBU, reported as data — targets and ratings, the market's view beside the model's.

Share price and the analyst range, 12 monthsAdjusted close, US dollars
$0.00$5.00$10.00Jan 26Apr 26Jul 26Oct 26CRBUHigh $13.00Median $4.50Low $1.00

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Data provided by Twelve Data

What Wall Street says6 analysts
2 Buy4 Hold0 Sell
Low $1.00Median $4.50High $13.00

The green dot is the last close — the median target sits +805.6% from it.

Recent analyst actionsNewest first

Of the 20 most recent actions, 1 moved their price target up and 3 moved it down.

DateFirmActionRatingTarget
8 Oct 2026HC Wainwright & Co.DowngradeNeutral—
7 Oct 2026Brookline CapitalDowngradeHold—
7 Oct 2026Leerink PartnersDowngradeMarket Perform$4.00 → $1.00
7 Oct 2026RBC CapitalDowngradeSector Perform$10 → $1.00
14 Aug 2026B of A SecuritiesMaintainsBuy$6.00 → $5.00
14 Aug 2026B of A SecuritiesMaintainsBuy—
11 May 2026HC Wainwright & Co.MaintainsBuy—
11 May 2026HC Wainwright & Co.MaintainsBuy$9.00 → $11
7 Apr 2026HC Wainwright & Co.ReiteratesBuy—
9 Mar 2026Evercore ISI GroupMaintainsOutperform—
2 Feb 2026Clear StreetInitiatesBuy—
5 Nov 2025HC Wainwright & Co.MaintainsBuy—
3 Nov 2025CitigroupMaintainsBuy—
28 Apr 2025HC Wainwright & Co.MaintainsBuy—
19 Mar 2025HC Wainwright & Co.ReiteratesBuy—
7 Jan 2025B of A SecuritiesMaintainsBuy—
26 Nov 2024CitigroupMaintainsBuy—
15 Nov 2024HC Wainwright & Co.ReiteratesBuy—
3 Sept 2024HC Wainwright & Co.ReiteratesBuy—
14 Aug 2024HC Wainwright & Co.ReiteratesBuy—

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Market Radar

This page is one stock. Monday covers all of them.

Computed off the Friday close and sent before the US open.

Market Radar reports the week’s largest rank changes across roughly 4,600 US stocks, the factor behind each one, and where the market went. CRBU appears on the weeks it earns a place.

Free, every Monday. Unsubscribe any time.

Performance

CRBU vs the S&P 500

Both lines are total return — dividends reinvested — so the comparison is honest on both sides.

Over the twelve months to 12 Oct 2026, Caribou Biosciences, Inc. returned −80.0% against +20.4% for the S&P 500, dividends included.

CRBU vs S&P 500, last 12 monthsTotal return, rebased to 100
20406080100120Jan 26Apr 26Jul 26Oct 26CRBUS&P 500

Download this chart as an image — free to reuse; link this page as the source.

Data provided by Twelve Data

Estimates

CRBU analyst estimate revisions

Not the forecast itself — the direction analysts are revising it. Revision direction is one of the model's factor families.

Which way the estimates are movingNext fiscal year
Analysts raising
2
Analysts cutting
0
Fundamentals

Caribou Biosciences, Inc. (CRBU) financial data

A margin means little on its own. Each bar marks where the figure sits across the whole US universe we score.

Valuation
Trailing P/E
−0.3×

Cheaper than 79% of US stocks

Price / sales
4.9×

Cheaper than 25% of US stocks

Price / book
0.5×

Cheaper than 84% of US stocks

EV / EBITDA
0.2×

Cheaper than 60% of US stocks

Growth & margins
Revenue growth (YoY)
−43.8%

Higher than 6% of US stocks

Earnings growth (YoY)
−43.8%

Higher than 12% of US stocks

Gross margin
—
Operating margin
−1690.4%

Higher than 4% of US stocks

Net margin
0.0%

Higher than 30% of US stocks

Returns & dividend
Return on equity
−78.3%

Higher than 16% of US stocks

Return on assets
−36.8%

Higher than 11% of US stocks

Dividend yield
0.0%

Higher than 1% of US dividend payers

Bars mark the percentile across the ~4,600 US stocks Ticker Nerd covers, among those reporting the figure.

Key statistics

Caribou Biosciences, Inc. (CRBU) statistics: revenue, profit & scale

The headline figures, each with its date. Every row carries its own link — cite it straight from here.

  • Caribou Biosciences, Inc. has a market value of $49.3M and an enterprise value of −$19.5M.

  • Revenue in the twelve months to 30 June 2026: $10.0M. The latest quarter shrank 43.8% year on year.

  • Net income over the same four quarters: −$103.4M, a −1030.4% net margin.

  • Diluted earnings per share, trailing twelve months: $−1.08.

  • Free cash flow in the twelve months to 30 June 2026: −$95.8M.

  • Shares outstanding: 106.0M.

  • Trailing P/E: −0.3×; forward P/E: −0.5× — the forward figure prices analyst consensus estimates, not reported earnings.

  • Forward dividend yield: 0.00%, paying out 0% of earnings.

  • Caribou Biosciences, Inc. employs 97 people — $103K of revenue per employee.

Statement figures: company filings via Twelve Data, four quarters to 30 June 2026 · market figures as at 13 Oct 2026

Data provided by Twelve Data

Peers

CRBU vs competitors

The nearest names by industry and size, scored by the same model — like for like.

Its peer group, ranked by the same modelBiotechnology
CompanyMarket capTKN rank
CRBUCaribou Biosciences, Inc.$49.3M
46
ACETAdicet Bio, Inc.$53.0M
36
HYPDHyperion DeFi, Inc.$52.6M
39
INKTMiNK Therapeutics, Inc.$52.3M
54
ALDXAldeyra Therapeutics, Inc.$54.6M
40
IBIOiBio, Inc.$55.0M
23
ELOXEloxx Pharmaceuticals, Inc.$56.1M
12

Look up any of the roughly 4,600 stocks we score.

The rank is the raw material. Whether the rules would actually own Caribou Biosciences, Inc. — and when they’d sell — is the membership. See the Ticker Nerd 20 →

News

Latest CRBU news & analysis

Caribou Biosciences to Evaluate Strategic Alternatives

GlobeNewsWire · 6 Oct 2026negative

Caribou Biosciences said it will evaluate strategic alternatives to maximize stockholder value and plans to discontinue its vispa-cel and CB-011 allogeneic CAR-T cell therapy programs.

Why it matters — The evaluation and planned discontinuations mark a significant change in Caribou’s programs and strategic direction.

Caribou Biosciences (CRBU) Loses 19.6% in 4 Weeks, Here's Why a Trend Reversal May be Around the Corner

Zacks Investment Research · 14 Sept 2026positive

Caribou Biosciences (CRBU) has declined 19.6% over the past four weeks and is now technically in oversold territory. The article suggests that this selling pressure may have exhausted, supported by Wall Street analysts revising earnings estimates higher, indicating a possible trend reversal.

Why it matters — A CRBU watcher would care because the oversold technical condition combined with upward earnings estimate revisions could signal that the stock's recent decline may be coming to an end.

Looking for Earnings Beat? Buy These 5 Top-Ranked Stocks

Zacks Investment Research · 31 Aug 2026positive

Zacks Investment Research identified CRBU among five top-ranked stocks (alongside ALL, W, BILL, and TWLO) that are likely to beat earnings expectations in their upcoming releases.

Why it matters — A positive earnings-beat outlook from a research firm could draw attention to CRBU ahead of its next quarterly report.

Caribou Biosciences, Inc. (CRBU) Reports Q2 Loss, Lags Revenue Estimates

Zacks Investment Research · 13 Aug 2026neutral

Caribou Biosciences reported a Q2 loss of $0.24 per share, narrower than the Zacks Consensus Estimate of a $0.33 loss and down from a $0.35 per-share loss a year earlier, though revenue lagged estimates.

Why it matters — The narrower-than-expected quarterly loss may signal improving operating performance, while the revenue shortfall highlights top-line headwinds investors in CRBU will want to monitor.

Caribou Biosciences Reports Second Quarter 2026 Financial Results and Provides Business Update

GlobeNewsWire · 13 Aug 2026positive

Caribou Biosciences reported its Q2 2026 financial results and presented phase 1 data for vispa-cel at EHA 2026, which showed the therapy's safety, efficacy, and durability are comparable to approved autologous CAR-T cell therapies. The company also presented CaMMouflage dose escalation data for CB-011, with initial dose expansion data expected in the second half of 2026.

Why it matters — A CRBU watcher would care because the EHA 2026 data reinforce vispa-cel's potential to compete with approved CAR-T therapies and provide a timeline for CB-011's next data readout in high-risk multiple myeloma patients.

FAQ

Frequently asked questions about CRBU stock

What is the CRBU stock price forecast for 2026-2027?

The 6 Wall Street analysts covering Caribou Biosciences, Inc. have a median 12-month price target of $4.5, with estimates ranging from $1 to $13. These are third-party analyst estimates, not Ticker Nerd forecasts, and they are frequently wrong.

Is CRBU stock a buy right now?

Of the 6 analysts covering Caribou Biosciences, Inc., 2 rate it a Buy, 4 a Hold and 0 a Sell. Ticker Nerd's systematic factor model ranks Caribou Biosciences, Inc. 46 out of 100 across roughly 4,600 US stocks as at 12 Oct 2026. None of this is personal advice — it does not consider your circumstances.

How does Ticker Nerd's model rank CRBU?

As at 12 Oct 2026, Caribou Biosciences, Inc. ranks 46 out of 100 on Ticker Nerd's systematic factor model — a percentile across roughly 4,600 US stocks, built from its factor families. Its strongest factor family is Growth (99 of 100).

Will CRBU stock go up?

No one can know that. What the data says: the median 12-month target from 6 analysts implies +805.6% from the last close, and Ticker Nerd's factor model ranks Caribou Biosciences, Inc. 46 out of 100 as at 12 Oct 2026. Analyst targets are third-party estimates and frequently wrong; none of this is personal advice.

What is the CRBU stock forecast for 2030?

No analyst covering Caribou Biosciences, Inc. publishes a 2030 price target — Wall Street targets run 12 to 18 months out. Sites quoting a 2030 price for CRBU are extrapolating price history, which says nothing about the business. The furthest attributed numbers are the current analyst targets: $1 to $13 over the next 12 months.

How has CRBU stock performed over the past year?

Caribou Biosciences, Inc. returned -80.0% over the 12 months to 12 Oct 2026, with dividends reinvested. Past performance does not indicate future returns.

What does Caribou Biosciences, Inc. do?

Caribou Biosciences, Inc. is a clinical-stage biopharmaceutical company focused on developing genome-edited allogeneic cell therapies using its CRISPR-based chRDNA platform.

What is the latest news on CRBU?

The most recent item we track (GlobeNewsWire, 6 Oct 2026): "Caribou Biosciences to Evaluate Strategic Alternatives". Caribou Biosciences said it will evaluate strategic alternatives to maximize stockholder value and plans to discontinue its vispa-cel and CB-011 allogeneic CAR-T cell therapy programs.

Company

About Caribou Biosciences, Inc.

Caribou Biosciences, Inc. is a clinical-stage biopharmaceutical company focused on developing genome-edited allogeneic cell therapies using its CRISPR-based chRDNA platform. The company works on off-the-shelf CAR-T and CAR-NK therapies designed to support precise cell engineering for difficult-to-treat diseases. Its current pipeline centers on hematologic malignancies and autoimmune disorders, with programs that include anti-CD19, anti-BCMA, and anti-CD371 cell therapies in clinical development. Caribou Biosciences also applies its gene-editing technology to advance broader research and therapeutic applications in biotechnology. Headquartered in Berkeley, California, the company operates as a single business segment centered on next-generation cell therapy development.

CEO Dr. Rachel E. Haurwitz Ph.D. · 97 employees · United States · https://cariboubio.com