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IONS Stock Forecast: Ionis Pharmaceuticals Inc. Price Predictions for 2025

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$28.40

+0.05 (0.18%)

IONS Stock Forecast 2025-2026

$28.40
Current Price
$4.51B
Market Cap
26 Ratings
Buy 17
Hold 8
Sell 1
Wall St Analyst Ratings

Distance to IONS Price Targets

+174.6%
To High Target of $78.00
+109.5%
To Median Target of $59.50
+30.3%
To Low Target of $37.00

IONS Price Momentum

+1.8%
1 Week Change
-13.2%
1 Month Change
-30.2%
1 Year Change
-18.8%
Year-to-Date Change
-45.7%
From 52W High of $52.34
+18.6%
From 52W Low of $23.95
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Latest IONS Stock Price Targets & Analyst Predictions

Based on our analysis of 32 Wall Street analysts, IONS has a bullish consensus with a median price target of $59.50 (ranging from $37.00 to $78.00). The overall analyst rating is Strong Buy (8.2/10). Currently trading at $28.40, the median forecast implies a 109.5% upside. This outlook is supported by 17 Buy, 8 Hold, and 1 Sell ratings.

Conversely, the most conservative target is provided by Salveen Richter at Goldman Sachs, suggesting a 30.3% upside.

Please note that analyst price targets are forward-looking estimates subject to substantial market, economic, and company-specific risks. Past performance does not guarantee future results, and actual stock performance may materially differ from these projections. Investors should conduct their own due diligence and consider their investment objectives and risk tolerance before making investment decisions.

IONS Analyst Ratings

17
Buy
8
Hold
1
Sell

IONS Price Target Range

Low
$37.00
Average
$59.50
High
$78.00
Current: $28.40

Latest IONS Stock Forecasts by Analyst

These are the latest 20 analyst ratings and price targets for IONS.

Date Firm Analyst Rating Change Price Target
Apr 15, 2025 Needham Joseph Stringer Buy Reiterates $60.00
Apr 8, 2025 Needham Joseph Stringer Buy Reiterates $60.00
Apr 7, 2025 HC Wainwright & Co. Mitchell Kapoor Buy Initiates $45.00
Apr 3, 2025 Guggenheim Debjit Chattopadhyay Buy Reiterates $0.00
Mar 31, 2025 Redburn Atlantic Joshua Smith Neutral Initiates $39.00
Mar 24, 2025 JP Morgan Jessica Fye Neutral Maintains $45.00
Mar 11, 2025 JP Morgan Jessica Fye Neutral Maintains $47.00
Feb 20, 2025 Needham Joseph Stringer Buy Reiterates $60.00
Feb 20, 2025 RBC Capital Luca Issi Outperform Reiterates $70.00
Feb 20, 2025 Citigroup David Lebowitz Buy Maintains $64.00
Feb 20, 2025 BMO Capital Kostas Biliouris Market Perform Maintains $45.00
Jan 15, 2025 RBC Capital Luca Issi Outperform Reiterates $70.00
Dec 20, 2024 Needham Joseph Stringer Buy Maintains $60.00
Nov 14, 2024 Piper Sandler Allison Bratzel Overweight Maintains $62.00
Nov 7, 2024 Needham Joseph Stringer Buy Reiterates $60.00
Nov 7, 2024 Wells Fargo Yanan Zhu Overweight Maintains $77.00
Oct 9, 2024 Guggenheim Debjit Chattopadhyay Buy Maintains $65.00
Sep 26, 2024 RBC Capital Luca Issi Outperform Reiterates $70.00
Aug 26, 2024 JP Morgan Jessica Fye Neutral Maintains $55.00
Aug 2, 2024 Guggenheim Debjit Chattopadhyay Buy Maintains $70.00

Ionis Pharmaceuticals Inc. (IONS) Competitors

The following stocks are similar to Ionis based on their market capitalization and industry sector. These similar stocks potentially provide investors with alternative investment opportunities within the same market segment.

Ionis Pharmaceuticals Inc. (IONS) Financial Data

Ionis Pharmaceuticals Inc. has a market capitalization of $4.51B with a P/E ratio of -9.3x. The company generates $705.14M in trailing twelve-month revenue with a -64.4% profit margin.

Revenue growth is -30.2% quarter-over-quarter, while maintaining an operating margin of -48.9% and return on equity of -93.1%.

Valuation Metrics

Market Cap $4.51B
Enterprise Value $4.17B
P/E Ratio -9.3x
PEG Ratio -7.6x
Price/Sales 6.4x

Growth & Margins

Revenue Growth (YoY) -30.2%
Gross Margin +98.3%
Operating Margin -48.9%
Net Margin -64.4%
EPS Growth N/A

Financial Health

Cash/Price Ratio +51.0%
Current Ratio 8.5x
Debt/Equity 332.9x
ROE -93.1%
ROA -9.9%
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Ionis Pharmaceuticals Inc. logo

Ionis Pharmaceuticals Inc. (IONS) Business Model

About Ionis Pharmaceuticals Inc.

What They Do

Develops RNA-targeted therapeutics for genetic disorders.

Business Model

Ionis Pharmaceuticals generates revenue by discovering and developing RNA-targeted therapeutics, primarily through its innovative antisense oligonucleotide technology. The company partners with leading pharmaceutical firms to enhance its drug pipeline and expand market reach, earning income from collaborations and potentially from product sales once approved.

Additional Information

Ionis has a strong pipeline of drugs addressing various diseases, including neurological, cardiovascular, metabolic, and cancer-related conditions. The company is at the forefront of personalized medicine, emphasizing the significance of genetic research in healthcare, which positions it as a key player in the biotechnology sector.

Company Information

Sector

Healthcare

Industry

Biotechnology

Employees

1,069

CEO

Dr. Brett P. Monia Ph.D.

Country

United States

IPO Year

1991

Ionis Pharmaceuticals Inc. (IONS) Latest News & Analysis

IONS stock latest news image
Quick Summary

Ionis Pharmaceuticals (IONS) saw a rise in share price with above-average trading volume, but recent earnings estimate revisions indicate potential weakness ahead.

Why It Matters

Ionis Pharmaceuticals' share price spike on high volume suggests short-term interest, but negative earnings revisions indicate potential long-term weakness, impacting future investment decisions.

Source: Zacks Investment Research
Market Sentiment: Positive
IONS stock latest news image
Quick Summary

Ionis Pharmaceuticals will host a webinar on April 14 at 11:00 a.m. ET discussing severe hypertriglyceridemia, featuring experts in lipidology and cardiology.

Why It Matters

Ionis Pharmaceuticals is addressing unmet medical needs in severe hypertriglyceridemia, potentially signaling advancements in treatment, which could impact stock performance and market position.

Source: Business Wire
Market Sentiment: Neutral
IONS stock latest news image
Quick Summary

Ionis Pharmaceuticals will participate in investor conferences on April 7, May 14, and May 21, 2025. Live webcasts will be available in the Investors & Media section of their website.

Why It Matters

Ionis Pharmaceuticals' participation in key investor conferences signals potential updates on strategies or developments, influencing investor sentiment and stock performance.

Source: Business Wire
Market Sentiment: Neutral
IONS stock latest news image
Quick Summary

Ionis has secured an undisclosed upfront payment from Sobi, along with potential milestone payments and a tiered royalty on future sales of the drug.

Why It Matters

Ionis securing an upfront payment and potential future earnings from milestone payments and royalties indicates strong partnership value, positively impacting its financial outlook and stock performance.

Source: Zacks Investment Research
Market Sentiment: Positive
IONS stock latest news image
Quick Summary

Ionis Pharmaceuticals has licensed Sobi exclusive rights to commercialize olezarsen outside the U.S., Canada, and China for treating familial chylomicronemia syndrome, while retaining U.S. rights.

Why It Matters

The licensing agreement expands Ionis Pharmaceuticals' market reach for olezarsen, potentially increasing revenue and strategic partnerships, enhancing its growth outlook.

Source: Business Wire
Market Sentiment: Neutral
IONS stock latest news image
Quick Summary

Ionis Pharmaceuticals (IONS) reported earnings 30 days ago. Investors may want to monitor upcoming developments for potential stock movement.

Why It Matters

Upcoming developments for Ionis Pharmaceuticals could influence stock performance, impacting investor sentiment and potential price movements. Earnings trends may signal future growth or risks.

Source: Zacks Investment Research
Market Sentiment: Positive

Frequently Asked Questions About IONS Stock

What is Ionis Pharmaceuticals Inc.'s (IONS) stock forecast for 2025?

Based on our analysis of 32 Wall Street analysts, Ionis Pharmaceuticals Inc. (IONS) has a median price target of $59.50. The highest price target is $78.00 and the lowest is $37.00.

Is IONS stock a good investment in 2025?

According to current analyst ratings, IONS has 17 Buy ratings, 8 Hold ratings, and 1 Sell ratings. The stock is currently trading at $28.40. Always conduct your own research and consider your investment goals before making investment decisions.

What is the long-term price prediction for IONS stock?

Wall Street analysts predict IONS stock could reach $59.50 in the next 12 months. This represents a 109.5% increase from the current price of $28.40. Please note that this is a projection by Wall Street analysts and not a guarantee.

What is Ionis Pharmaceuticals Inc.'s business model?

Ionis Pharmaceuticals generates revenue by discovering and developing RNA-targeted therapeutics, primarily through its innovative antisense oligonucleotide technology. The company partners with leading pharmaceutical firms to enhance its drug pipeline and expand market reach, earning income from collaborations and potentially from product sales once approved.

What is the highest forecasted price for IONS Ionis Pharmaceuticals Inc.?

Price targets from Wall Street analysts for IONS are not currently available. The stock is trading at $28.40.

What is the lowest forecasted price for IONS Ionis Pharmaceuticals Inc.?

The lowest price target for IONS is $37.00 from Salveen Richter at Goldman Sachs, which represents a 30.3% increase from the current price of $28.40.

What is the overall IONS consensus from analysts for Ionis Pharmaceuticals Inc.?

The overall analyst consensus for IONS is bullish. Out of 32 Wall Street analysts, 17 rate it as Buy, 8 as Hold, and 1 as Sell, with a median price target of $59.50.

How accurate are IONS stock price projections?

Stock price projections, including those for Ionis Pharmaceuticals Inc., are based on various factors including financial models, market conditions, and analyst forecasts. While these predictions provide valuable insights, they should be considered alongside your own research and risk tolerance.

Important Disclaimer

The information provided by Ticker Nerd is for educational and informational purposes only. It should not be considered financial or investment advice. Past performance is not indicative of future results. Always conduct your own research and consult with a qualified financial advisor before making any investment decisions. Analyst ratings and price forecasts are sourced from Wall St analysts and other experts. These projections are speculative and do not guarantee future stock performance.

Last updated: April 19, 2025 9:52 PM UTC
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