Opus Genetics Completes Patient Enrollment in Registrational Phase 3 Trial of OPGx-LCA5 for LCA5-Associated Inherited Retinal Disease
Opus Genetics announced completion of patient enrollment in its registrational Phase 3 clinical trial of OPGx-LCA5, an investigational gene therapy for LCA5-associated inherited retinal disease. Topline six-month efficacy data are expected by the end of 2027, with a possible BLA submission based on six-month data and 12-month durability data provided during review.
Why it matters — A fully enrolled registrational Phase 3 trial for a gene therapy targeting LCA5-associated inherited retinal disease advances the path toward a potential regulatory submission for a currently unaddressed form of retinal disease.