MDGLMDGLHealthcare · Biotechnology

MDGL Stock Forecast: Madrigal Pharmaceuticals, Inc. Price Predictions for 2026-2027

Last close, 3 Aug 2026
$482
+3.14% on the day

The 17 Wall Street analysts covering Madrigal Pharmaceuticals, Inc. hold a median 12-month price target of $650 — +34.9% from the last close. Ticker Nerd's systematic factor model, run across ~4,600 US stocks, ranks it 67 of 100 as at 1 Aug 2026 — in the upper half.

Market cap
$10.8B
Ticker Nerd rank
67 / 100
Median analyst target
$650
Analysts covering
17
Total return, dividends reinvested
1W
−12.6%
1M
−8.7%
YTD
−17.2%
1Y
+59.5%
From 52W high
−20.0%
From 52W low
+54.4%
$312
$603
52-week range, adjusted closes · the dot is the last close
Ticker Nerd rank

MDGL stock analysis: one number for the whole business

Consensus tells you what everyone already believes. The model scores Madrigal Pharmaceuticals, Inc. on its factor families — the same systematic rank behind the Ticker Nerd portfolio.

Where the model ranks itAs at 1 Aug 2026
67 / 100

Percentile across ~4,600 US stocks on Ticker Nerd’s systematic factor model. Higher is better. How the model is built and tested

Volatility
93
Value
93
Quality
85
Revisions
77
Momentum
69
Growth
45
Accruals
40
Size
15
Issuance
13

Volatility (93): The share price has been relatively steady.

Issuance (13): The company has been issuing shares or taking on financing, diluting existing holders.

The rank is the raw material. Whether the rules would actually own Madrigal Pharmaceuticals, Inc. — and when they’d sell — is the membership.

Wall Street

MDGL stock forecast 2026-2027: analyst price targets & predictions

The bullish and bearish analyst opinions on MDGL, reported as data — targets and ratings, the market's view beside the model's.

Share price and the analyst range, 12 monthsAdjusted close, US dollars
$200$400$600$800$1,000Oct 25Jan 26Apr 26Jul 26MDGLHigh $964Median $650Low $553

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

What Wall Street says17 analysts
15 Buy2 Hold0 Sell
Low $553Median $650High $964

The green dot is the last close — the median target sits +34.9% from it.

Recent analyst actionsNewest first

Of the 20 most recent actions, 1 moved their price target up and 2 moved it down.

DateFirmActionRatingTarget
3 Aug 2026BarclaysMaintainsOverweight$964$962
29 July 2026Canaccord GenuityMaintainsBuy$578$587
27 July 2026Wells FargoInitiatesOverweight$685
11 June 2026B of A SecuritiesMaintainsNeutral
11 June 2026B of A SecuritiesMaintainsNeutral$550$542
13 May 2026Truist SecuritiesMaintainsBuy
7 May 2026Canaccord GenuityMaintainsBuy
7 May 2026Evercore ISI GroupMaintainsOutperform
6 May 2026HC Wainwright & Co.ReiteratesBuy
20 Feb 2026B of A SecuritiesMaintainsNeutral
28 Jan 2026BarclaysInitiatesOverweight
20 Jan 2026CitizensMaintainsMarket Outperform
19 Dec 2025Piper SandlerMaintainsOverweight
11 Dec 2025B. Riley SecuritiesMaintainsBuy
21 Nov 2025HC Wainwright & Co.MaintainsBuy
20 Nov 2025OppenheimerMaintainsOutperform
19 Nov 2025Truist SecuritiesMaintainsBuy
13 Nov 2025Canaccord GenuityMaintainsBuy
11 Nov 2025HC Wainwright & Co.MaintainsBuy
5 Nov 2025Cantor FitzgeraldUpgradeOverweight

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Estimates

MDGL analyst estimate revisions

Not the forecast itself — the direction analysts are revising it. Revision direction is one of the model's factor families.

Which way the estimates are movingNext fiscal year
Analysts raising
1
Analysts cutting
2
Fundamentals

Madrigal Pharmaceuticals, Inc. (MDGL) financial data

A margin means little on its own. Each bar marks where the figure sits across the whole US universe we score.

Valuation
Trailing P/E
−36.4×

Cheaper than 98% of US stocks

Price / sales
8.4×

Cheaper than 16% of US stocks

Price / book
26.0×

Cheaper than 4% of US stocks

EV / EBITDA
−32.1×

Cheaper than 92% of US stocks

Growth & margins
Revenue growth (YoY)
71.2%

Higher than 91% of US stocks

Earnings growth (YoY)
71.2%

Higher than 82% of US stocks

Gross margin
89.0%

Higher than 96% of US stocks

Operating margin
−15.5%

Higher than 24% of US stocks

Net margin
−25.3%

Higher than 14% of US stocks

Returns & dividend
Return on equity
−53.3%

Higher than 20% of US stocks

Return on assets
−17.8%

Higher than 21% of US stocks

Dividend yield

Bars mark the percentile across the ~4,600 US stocks Ticker Nerd covers, among those reporting the figure.

Peers

MDGL vs competitors

The nearest names by industry and size, scored by the same model — like for like.

Its peer group, ranked by the same modelBiotechnology
CompanyMarket capTKN rank
MDGLMadrigal Pharmaceuticals, Inc.$10.8B
67
SMMTSummit Therapeutics, Inc.$10.4B
18
AXSMAxsome Therapeutics, Inc.$11.2B
74
TECHBio-Techne Corp.$11.2B
88
APGEApogee Therapeutics, Inc.$10.1B
45
KRYSKrystal Biotech, Inc.$10.1B
73
BMRNBioMarin Pharmaceutical, Inc.$11.5B
70
Market Radar

This page is one stock. Monday covers all of them.

Computed off the Friday close and sent before the US open.

Market Radar reports the week’s largest rank changes across roughly 4,600 US stocks, the factor behind each one, and where the market went. MDGL appears on the weeks it earns a place.

Free, every Monday. Unsubscribe any time.

News

Latest MDGL news & analysis

MDGL Stock Down Despite Q2 Beat, MASH Drug Drives Top-Line Y/Y Growth

Zacks Investment Research · 31 July 2026negative

Madrigal Pharmaceuticals beat Q2 estimates, driven by Rezdiffra sales which lifted revenues 71% year over year, but MDGL stock fell as investors weighed concerns about slower commercial growth.

Why it matters — The stock decline despite a quarterly beat highlights investor focus on the pace of Rezdiffra's commercial rollout, a key metric for MDGL's near-term prospects.

Madrigal Pharmaceuticals Q2 Earnings Call Highlights

MarketBeat · 30 July 2026positive

Madrigal Pharmaceuticals reported second-quarter 2026 net sales of $364.3 million for Rezdiffra, a 71% increase from a year earlier, driven by expanded patient numbers receiving its MASH treatment.

Why it matters — The significant sales growth for Rezdiffra signals expanding adoption of Madrigal's first-in-class MASH treatment, a key product for the company's future performance.

Madrigal Pharmaceuticals, Inc. (MDGL) Q2 2026 Earnings Call Transcript

Seeking Alpha · 30 July 2026neutral

Madrigal Pharmaceuticals held its Q2 2026 earnings call, and Seeking Alpha published a transcript of the event.

Why it matters — Earnings call transcripts provide investors and analysts with management's detailed commentary on the company's quarterly financial performance and business outlook.

Madrigal (MDGL) Reports Q2 Loss, Beats Revenue Estimates

Zacks Investment Research · 30 July 2026neutral

Madrigal Pharmaceuticals reported a second-quarter loss of $1.99 per share, which was narrower than the Zacks Consensus Estimate of a $2.55 loss, though wider than the $1.9 loss per share from the same quarter a year ago. Revenue for the quarter exceeded analyst expectations.

Why it matters — For MDGL watchers, the smaller-than-expected quarterly loss and revenue beat may indicate improving financial momentum relative to analyst forecasts.

Madrigal Pharmaceuticals Reports Second-Quarter 2026 Financial Results and Provides Corporate Updates

GlobeNewsWire · 30 July 2026neutral

Madrigal Pharmaceuticals announced its second-quarter 2026 financial results and provided corporate updates. The company continues to focus on developing novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH).

Why it matters — MDGL watchers would care because quarterly financial results and corporate updates offer insight into the company's progress with its MASH-focused pipeline and overall financial health.

FAQ

Frequently asked questions about MDGL stock

What is the MDGL stock price forecast for 2026-2027?

The 17 Wall Street analysts covering Madrigal Pharmaceuticals, Inc. have a median 12-month price target of $650, with estimates ranging from $553 to $964. These are third-party analyst estimates, not Ticker Nerd forecasts, and they are frequently wrong.

Is MDGL stock a buy right now?

Of the 17 analysts covering Madrigal Pharmaceuticals, Inc., 15 rate it a Buy, 2 a Hold and 0 a Sell. Ticker Nerd's systematic factor model ranks Madrigal Pharmaceuticals, Inc. 67 out of 100 across roughly 4,600 US stocks as at 1 Aug 2026. None of this is personal advice — it does not consider your circumstances.

How does Ticker Nerd's model rank MDGL?

As at 1 Aug 2026, Madrigal Pharmaceuticals, Inc. ranks 67 out of 100 on Ticker Nerd's systematic factor model — a percentile across roughly 4,600 US stocks, built from its factor families. Its strongest factor family is Volatility (93 of 100).

Will MDGL stock go up?

No one can know that. What the data says: the median 12-month target from 17 analysts implies +34.9% from the last close, and Ticker Nerd's factor model ranks Madrigal Pharmaceuticals, Inc. 67 out of 100 as at 1 Aug 2026. Analyst targets are third-party estimates and frequently wrong; none of this is personal advice.

What is the MDGL stock forecast for 2030?

No analyst covering Madrigal Pharmaceuticals, Inc. publishes a 2030 price target — Wall Street targets run 12 to 18 months out. Sites quoting a 2030 price for MDGL are extrapolating price history, which says nothing about the business. The furthest attributed numbers are the current analyst targets: $553 to $964 over the next 12 months.

How has MDGL stock performed over the past year?

Madrigal Pharmaceuticals, Inc. returned +59.5% over the 12 months to 3 Aug 2026, with dividends reinvested. Past performance does not indicate future returns.

What does Madrigal Pharmaceuticals, Inc. do?

Madrigal Pharmaceuticals, Inc. is a biopharmaceutical company focused on developing and commercializing innovative therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), also known as non-alcoholic steatohepatitis (NASH), and related liver conditions.

What is the latest news on MDGL?

The most recent item we track (Zacks Investment Research, 31 July 2026): "MDGL Stock Down Despite Q2 Beat, MASH Drug Drives Top-Line Y/Y Growth". Madrigal Pharmaceuticals beat Q2 estimates, driven by Rezdiffra sales which lifted revenues 71% year over year, but MDGL stock fell as investors weighed concerns about slower commercial growth.

Company

About Madrigal Pharmaceuticals, Inc.

Madrigal Pharmaceuticals, Inc. is a biopharmaceutical company focused on developing and commercializing innovative therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), also known as non-alcoholic steatohepatitis (NASH), and related liver conditions. Its lead product, Rezdiffra (resmetirom), is a liver-directed thyroid hormone receptor beta agonist approved for treating adults with MASH and moderate to advanced liver fibrosis, marking it as the first FDA-approved therapy in this category. The company has also expanded its pipeline through a global licensing agreement for ervogastat, an oral DGAT-2 inhibitor in Phase 2 development, to complement its MASH treatment offerings. Madrigal Pharmaceuticals, Inc. targets the growing demand in the metabolic liver disease market, where it plays a pioneering role with rapid commercialization efforts, including approvals in the United States and Europe. Headquartered in West Conshohocken, Pennsylvania, and founded in 2000, the company concentrates on addressing unmet needs in cardiovascular, metabolic, and liver diseases through targeted oral therapies.

CEO Mr. William J. Sibold · 915 employees · United States · https://www.madrigalpharma.com