ZNTLZNTLHealthcare · Biotechnology

ZNTL Stock Forecast: Zentalis Pharmaceuticals, Inc. Price Predictions for 2026-2027

Last close, 11 Sept 2026
$3.50
−2.51% on the day

The 9 Wall Street analysts covering Zentalis Pharmaceuticals, Inc. hold a median 12-month price target of $6 — +71.4% from the last close. Ticker Nerd's systematic factor model, run across ~4,600 US stocks, ranks it 62 of 100 as at 12 Sept 2026 — in the upper half.

Market cap
$331.4M
Ticker Nerd rank
62 / 100
Median analyst target
$6.00
Analysts covering
9
Revenue$0.0
Operating income−$44.4M
Net income−$42.3M
Free cash flow−$37.2M
Quarterly, 8 quarters to 30 June 2026 · latest quarter's figure shown
Total return, dividends reinvested
1W
−14.8%
1M
−14.8%
YTD
+159.3%
1Y
+124.4%
From 52W high
−47.0%
From 52W low
+173.4%
$1.28
$6.61
52-week range, adjusted closes · the dot is the last close
Ticker Nerd rank

ZNTL stock analysis: one number for the whole business

Consensus tells you what everyone already believes. The model scores Zentalis Pharmaceuticals, Inc. on its factor families — the same systematic rank behind the Ticker Nerd portfolio.

Where the model ranks itAs at 12 Sept 2026
62 / 100

Percentile across ~4,600 US stocks on Ticker Nerd’s systematic factor model. Higher is better. How the model is built and tested

Momentum
88
Issuance
87
Accruals
73
Size
60
Value
56
Quality
55
Growth
45
Revisions
26
Volatility
8

Momentum (88): The shares have been drifting up relative to others.

Volatility (8): The share price moves around a lot.

Built and run by Aslam Ghouse, an ex-Goldman Sachs quant trader with fourteen years in markets.

Wall Street

ZNTL stock forecast 2026-2027: analyst price targets & predictions

The bullish and bearish analyst opinions on ZNTL, reported as data — targets and ratings, the market's view beside the model's.

Share price and the analyst range, 12 monthsAdjusted close, US dollars
$0.00$2.00$4.00$6.00$8.00$10.00Oct 25Jan 26Apr 26Jul 26ZNTLHigh $10.00Median $6.00Low $4.00

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Data provided by Twelve Data

What Wall Street says9 analysts
4 Buy5 Hold0 Sell
Low $4.00Median $6.00High $10.00

The green dot is the last close — the median target sits +71.4% from it.

Recent analyst actionsNewest first
DateFirmActionRatingTarget
23 July 2026Rodman & RenshawInitiatesBuy$11
17 July 2026MizuhoInitiatesOutperform$8.00
10 Apr 2026GuggenheimMaintainsBuy
27 Mar 2026GuggenheimReiteratesBuy
12 Nov 2025Morgan StanleyMaintainsEqual-Weight
7 Aug 2025Wells FargoMaintainsEqual-Weight
15 May 2025HC Wainwright & Co.ReiteratesBuy
15 May 2025WedbushReiteratesNeutral
28 Mar 2025WedbushReiteratesNeutral
27 Mar 2025HC Wainwright & Co.ReiteratesBuy
17 Mar 2025HC Wainwright & Co.ReiteratesBuy
30 Jan 2025Wells FargoMaintainsEqual-Weight
29 Jan 2025HC Wainwright & Co.MaintainsBuy
28 Jan 2025UBSMaintainsNeutral
15 Nov 2024GuggenheimMaintainsBuy
15 Nov 2024HC Wainwright & Co.ReiteratesBuy
16 Sept 2024OppenheimerReiteratesOutperform
12 Aug 2024HC Wainwright & Co.ReiteratesBuy
12 Aug 2024WedbushUpgradeNeutral
20 June 2024UBSDowngradeNeutral

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Market Radar

This page is one stock. Monday covers all of them.

Computed off the Friday close and sent before the US open.

Market Radar reports the week’s largest rank changes across roughly 4,600 US stocks, the factor behind each one, and where the market went. ZNTL appears on the weeks it earns a place.

Free, every Monday. Unsubscribe any time.

Performance

ZNTL vs the S&P 500

Both lines are total return — dividends reinvested — so the comparison is honest on both sides.

Over the twelve months to 11 Sept 2026, Zentalis Pharmaceuticals, Inc. returned +124.4% against +17.5% for the S&P 500, dividends included.

ZNTL vs S&P 500, last 12 monthsTotal return, rebased to 100
100200300400Oct 25Jan 26Apr 26Jul 26ZNTLS&P 500

Download this chart as an image — free to reuse; link this page as the source.

Data provided by Twelve Data

Estimates

ZNTL analyst estimate revisions

Not the forecast itself — the direction analysts are revising it. Revision direction is one of the model's factor families.

Which way the estimates are movingNext fiscal year
Analysts raising
0
Analysts cutting
1
Fundamentals

Zentalis Pharmaceuticals, Inc. (ZNTL) financial data

A margin means little on its own. Each bar marks where the figure sits across the whole US universe we score.

Valuation
Trailing P/E
−1.8×

Cheaper than 85% of US stocks

Price / sales
Price / book
1.8×

Cheaper than 50% of US stocks

EV / EBITDA
−0.8×

Cheaper than 66% of US stocks

Growth & margins
Revenue growth (YoY)
Earnings growth (YoY)
Gross margin
Operating margin
0.0%

Higher than 32% of US stocks

Net margin
0.0%

Higher than 30% of US stocks

Returns & dividend
Return on equity
−66.7%

Higher than 18% of US stocks

Return on assets
−33.2%

Higher than 12% of US stocks

Dividend yield

Bars mark the percentile across the ~4,600 US stocks Ticker Nerd covers, among those reporting the figure.

Key statistics

Zentalis Pharmaceuticals, Inc. (ZNTL) statistics: revenue, profit & scale

The headline figures, each with its date. Every row carries its own link — cite it straight from here.

  • Zentalis Pharmaceuticals, Inc. has a market value of $331.4M and an enterprise value of $114.7M.

  • Revenue in the twelve months to 30 June 2026: $0.0.

  • Net income over the same four quarters: −$139.5M.

  • Free cash flow in the twelve months to 30 June 2026: −$128.1M.

  • Shares outstanding: 71.7M.

  • Trailing P/E: −1.8×; forward P/E: −1.9× — the forward figure prices analyst consensus estimates, not reported earnings.

  • Zentalis Pharmaceuticals, Inc. employs 106 people.

Statement figures: company filings via Twelve Data, four quarters to 30 June 2026 · market figures as at 13 Sept 2026

Data provided by Twelve Data

Peers

ZNTL vs competitors

The nearest names by industry and size, scored by the same model — like for like.

Its peer group, ranked by the same modelBiotechnology
CompanyMarket capTKN rank
ZNTLZentalis Pharmaceuticals, Inc.$331.4M
62
LXEOLexeo Therapeutics, Inc.$333.7M
29
QTTBQ32 Bio, Inc.$330.4M
85
IKTInhibikase Therapeutics, Inc.$326.5M
33
OCGNOcugen, Inc.$345.3M
22
XFORX4 Pharmaceuticals, Inc.$347.0M
62
IPSCCentury Therapeutics, Inc.$348.5M
39

Look up any of the roughly 4,600 stocks we score.

The rank is the raw material. Whether the rules would actually own Zentalis Pharmaceuticals, Inc. — and when they’d sell — is the membership. See the Ticker Nerd 20 →

News

Latest ZNTL news & analysis

Zentalis Pharmaceuticals to Participate in Upcoming Investor Conferences

GlobeNewsWire · 2 Sept 2026neutral

Zentalis Pharmaceuticals announced that members of its management team will participate in upcoming investor conferences. The company is a clinical oncology innovator advancing late-stage development of azenosertib, an investigational first-in-class WEE1 inhibitor for ovarian cancer.

Why it matters — ZNTL watchers would care because management participation at investor conferences offers visibility into the company's late-stage azenosertib development program for ovarian cancer.

Zentalis Pharmaceuticals Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

GlobeNewsWire · 1 Sept 2026neutral

Zentalis Pharmaceuticals announced that its Compensation Committee granted non-qualified stock options to purchase an aggregate of 269,000 shares of common stock to four newly hired employees on September 1, 2026. The grants were made under the company's 2022 Employment Inducement Incentive Award Plan as an inducement for the individuals to join the company, in accordance with Nasdaq Listing Rule 5635(c)(4).

Why it matters — ZNTL watchers would care because the inducement grants signal the company's ongoing headcount expansion and hiring activity as it advances its lead oncology candidate azenosertib.

Zentalis Pharmaceuticals: Data Due H1 '27 Will Clarify Prospects Of Azenosertib

Seeking Alpha · 31 Aug 2026positive

Zentalis Pharmaceuticals receives a cautious Buy rating based on the potential of azenosertib in Cyclin E1-positive platinum-resistant ovarian cancer. Pivotal data from the DENALI and ASPENOVA trials is expected in H1 2027, and a recent $93m capital raise extends the company's cash runway into 2028.

Why it matters — ZNTL watchers would care because the H1 2027 azenosertib data represents a key catalyst that could determine the drug's path toward FDA approval, while the capital raise reduces near-term funding risk.

Zentalis Pharmaceuticals Announces Closing of Underwritten Public Offering, Including Full Exercise of Underwriters' Option to Purchase Additional Shares

GlobeNewsWire · 17 Aug 2026neutral

Zentalis Pharmaceuticals announced the closing of its underwritten public offering of 26,450,000 shares of common stock, including 3,450,000 shares from the full exercise of the underwriters' option to purchase additional shares. The shares were sold at $3.50 per share, generating approximately $92.6 million in gross proceeds before deductions.

Why it matters — The completed offering provides Zentalis with additional capital to fund its ongoing clinical development of azenosertib.

Zentalis Pharmaceuticals Announces Pricing of Underwritten Public Offering

GlobeNewsWire · 14 Aug 2026neutral

Zentalis Pharmaceuticals announced the pricing of an underwritten public offering of 23,000,000 shares of common stock at $3.50 per share, with expected gross proceeds of approximately $80.5 million before underwriting discounts and expenses. The offering is expected to close on August 17, 2026, and includes a 30-day underwriter option for up to an additional 3,450,000 shares.

Why it matters — ZNTL watchers would care because the offering represents a capital raise that could fund the company's ongoing clinical development of its azenosertib program.

FAQ

Frequently asked questions about ZNTL stock

What is the ZNTL stock price forecast for 2026-2027?

The 9 Wall Street analysts covering Zentalis Pharmaceuticals, Inc. have a median 12-month price target of $6, with estimates ranging from $4 to $10. These are third-party analyst estimates, not Ticker Nerd forecasts, and they are frequently wrong.

Is ZNTL stock a buy right now?

Of the 9 analysts covering Zentalis Pharmaceuticals, Inc., 4 rate it a Buy, 5 a Hold and 0 a Sell. Ticker Nerd's systematic factor model ranks Zentalis Pharmaceuticals, Inc. 62 out of 100 across roughly 4,600 US stocks as at 12 Sept 2026. None of this is personal advice — it does not consider your circumstances.

How does Ticker Nerd's model rank ZNTL?

As at 12 Sept 2026, Zentalis Pharmaceuticals, Inc. ranks 62 out of 100 on Ticker Nerd's systematic factor model — a percentile across roughly 4,600 US stocks, built from its factor families. Its strongest factor family is Momentum (88 of 100).

Will ZNTL stock go up?

No one can know that. What the data says: the median 12-month target from 9 analysts implies +71.4% from the last close, and Ticker Nerd's factor model ranks Zentalis Pharmaceuticals, Inc. 62 out of 100 as at 12 Sept 2026. Analyst targets are third-party estimates and frequently wrong; none of this is personal advice.

What is the ZNTL stock forecast for 2030?

No analyst covering Zentalis Pharmaceuticals, Inc. publishes a 2030 price target — Wall Street targets run 12 to 18 months out. Sites quoting a 2030 price for ZNTL are extrapolating price history, which says nothing about the business. The furthest attributed numbers are the current analyst targets: $4 to $10 over the next 12 months.

How has ZNTL stock performed over the past year?

Zentalis Pharmaceuticals, Inc. returned +124.4% over the 12 months to 11 Sept 2026, with dividends reinvested. Past performance does not indicate future returns.

What does Zentalis Pharmaceuticals, Inc. do?

Zentalis Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing small molecule therapeutics for cancer.

What is the latest news on ZNTL?

The most recent item we track (GlobeNewsWire, 2 Sept 2026): "Zentalis Pharmaceuticals to Participate in Upcoming Investor Conferences". Zentalis Pharmaceuticals announced that members of its management team will participate in upcoming investor conferences. The company is a clinical oncology innovator advancing late-stage development of azenosertib, an investigational first-in-class WEE1 inhibitor for ovarian cancer.

Company

About Zentalis Pharmaceuticals, Inc.

Zentalis Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing small molecule therapeutics for cancer. Its current portfolio centers on azenosertib, an oral investigational WEE1 inhibitor being advanced in studies across ovarian cancer and other solid tumors. The company’s research emphasizes biomarker-driven oncology, with a focus on targeted, non-chemotherapy treatment approaches designed to address difficult-to-treat cancers. Zentalis also develops additional oncology candidates, including programs targeting hematologic malignancies and other cancer pathways, supported by its internal discovery capabilities and clinical development expertise. Headquartered in San Diego, California, Zentalis Pharmaceuticals plays a specialized role in the oncology market by advancing precision medicine candidates from discovery into late-stage clinical evaluation.

CEO Ms. Julie M. Eastland M.B.A. · 106 employees · United States · https://zentalis.com