Q32 Bio Presents Results from Part B of the SIGNAL-AA Clinical Trial of Bempikibart in Alopecia Areata in a Late-Breaker at the European Academy of Dermatology and Venereology Congress 2026
Q32 Bio presented late-breaking results from Part B of the SIGNAL-AA Phase 2a trial of bempikibart in alopecia areata at the European Academy of Dermatology and Venereology Congress 2026, including data from the 36-week treatment period and a 16-week off-drug period. The company reported clinically meaningful efficacy on primary and key secondary endpoints, durable responses, biomarker and biopsy findings consistent with its mechanism of action, and a generally well-tolerated safety profile with no new safety signals.
Why it matters — The positive efficacy and durability data support Q32 Bio's plan to advance bempikibart into a registration-directed program for alopecia areata beginning in the first half of 2027.