ACTUACTUHealthcare · Biotechnology

ACTU Stock Forecast: Actuate Therapeutics, Inc. Price Predictions for 2026-2027

Last close, 11 Sept 2026
$1.07
−6.96% on the day

The 3 Wall Street analysts covering Actuate Therapeutics, Inc. hold a median 12-month price target of $12 — +1021.5% from the last close. Ticker Nerd's systematic factor model, run across ~4,600 US stocks, ranks it 31 of 100 as at 12 Sept 2026 — in the lower half. The Street sees upside; the factor read is a caution. That gap is the story on this page.

Market cap
$25.7M
Ticker Nerd rank
31 / 100
Median analyst target
$12
Analysts covering
3
Revenue$0.0
Operating income−$4.9M
Net income−$4.9M
Free cash flow−$4.4M
Quarterly, 8 quarters to 30 June 2026 · latest quarter's figure shown
Total return, dividends reinvested
1W
−21.9%
1M
+5.9%
YTD
−82.5%
1Y
−84.6%
From 52W high
−86.8%
From 52W low
+10.3%
$0.97
$8.09
52-week range, adjusted closes · the dot is the last close
Ticker Nerd rank

ACTU stock analysis: one number for the whole business

Consensus tells you what everyone already believes. The model scores Actuate Therapeutics, Inc. on its factor families — the same systematic rank behind the Ticker Nerd portfolio.

Where the model ranks itAs at 12 Sept 2026
31 / 100

Percentile across ~4,600 US stocks on Ticker Nerd’s systematic factor model. Higher is better. How the model is built and tested

Size
87
Growth
77
Revisions
57
Issuance
40
Accruals
35
Value
31
Volatility
24
Momentum
15
Quality
12

Size (87): Smaller than most of the companies we track.

Quality (12): Profits are thin or unreliable for the size of the business, or they are not turning into cash.

Built and run by Aslam Ghouse, an ex-Goldman Sachs quant trader with fourteen years in markets.

Wall Street

ACTU stock forecast 2026-2027: analyst price targets & predictions

The bullish and bearish analyst opinions on ACTU, reported as data — targets and ratings, the market's view beside the model's.

Share price and the analyst range, 12 monthsAdjusted close, US dollars
$0.00$5.00$10.00$15.00Oct 25Jan 26Apr 26Jul 26ACTUHigh $15Median $12Low $8

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Data provided by Twelve Data

What Wall Street says3 analysts
3 Buy0 Hold0 Sell
Low $8Median $12High $15

The green dot is the last close — the median target sits +1021.5% from it.

Recent analyst actionsNewest first
DateFirmActionRatingTarget
18 Aug 2026HC Wainwright & Co.ReiteratesBuy$15
30 July 2026Rodman & RenshawInitiatesBuy$6.00
30 July 2026Rodman & RenshawInitiatesBuy
18 May 2026HC Wainwright & Co.ReiteratesBuy$15
18 May 2026HC Wainwright & Co.ReiteratesBuy
22 Apr 2026HC Wainwright & Co.ReiteratesBuy
13 Apr 2026HC Wainwright & Co.MaintainsBuy
19 Nov 2025HC Wainwright & Co.ReiteratesBuy
23 Sept 2025HC Wainwright & Co.ReiteratesBuy
26 Aug 2025B. Riley SecuritiesInitiatesBuy
18 Aug 2025HC Wainwright & Co.ReiteratesBuy
17 Mar 2025HC Wainwright & Co.InitiatesBuy

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Market Radar

This page is one stock. Monday covers all of them.

Computed off the Friday close and sent before the US open.

Market Radar reports the week’s largest rank changes across roughly 4,600 US stocks, the factor behind each one, and where the market went. ACTU appears on the weeks it earns a place.

Free, every Monday. Unsubscribe any time.

Performance

ACTU vs the S&P 500

Both lines are total return — dividends reinvested — so the comparison is honest on both sides.

Over the twelve months to 11 Sept 2026, Actuate Therapeutics, Inc. returned −84.6% against +17.5% for the S&P 500, dividends included.

ACTU vs S&P 500, last 12 monthsTotal return, rebased to 100
020406080100120Oct 25Jan 26Apr 26Jul 26ACTUS&P 500

Download this chart as an image — free to reuse; link this page as the source.

Data provided by Twelve Data

Estimates

ACTU analyst estimate revisions

Not the forecast itself — the direction analysts are revising it. Revision direction is one of the model's factor families.

Which way the estimates are movingNext fiscal year
Analysts raising
1
Analysts cutting
1
Fundamentals

Actuate Therapeutics, Inc. (ACTU) financial data

A margin means little on its own. Each bar marks where the figure sits across the whole US universe we score.

Valuation
Trailing P/E
6.8×

Cheaper than 63% of US stocks

Price / sales
Price / book
26.1×

Cheaper than 4% of US stocks

EV / EBITDA
−1.0×

Cheaper than 67% of US stocks

Growth & margins
Revenue growth (YoY)
Earnings growth (YoY)
Gross margin
Operating margin
0.0%

Higher than 32% of US stocks

Net margin
0.0%

Higher than 30% of US stocks

Returns & dividend
Return on equity
−280.5%

Higher than 5% of US stocks

Return on assets
−213.4%

Higher than 1% of US stocks

Dividend yield

Bars mark the percentile across the ~4,600 US stocks Ticker Nerd covers, among those reporting the figure.

Key statistics

Actuate Therapeutics, Inc. (ACTU) statistics: revenue, profit & scale

The headline figures, each with its date. Every row carries its own link — cite it straight from here.

  • Actuate Therapeutics, Inc. has a market value of $25.7M and an enterprise value of $21.3M.

  • Revenue in the twelve months to 30 June 2026: $0.0.

  • Net income over the same four quarters: −$20.5M.

  • Free cash flow in the twelve months to 30 June 2026: −$19.8M.

  • Shares outstanding: 24.0M.

  • Trailing P/E: 6.8×; forward P/E: −1.6× — the forward figure prices analyst consensus estimates, not reported earnings.

  • Actuate Therapeutics, Inc. employs 12 people.

Statement figures: company filings via Twelve Data, four quarters to 30 June 2026 · market figures as at 14 Sept 2026

Data provided by Twelve Data

Peers

ACTU vs competitors

The nearest names by industry and size, scored by the same model — like for like.

Its peer group, ranked by the same modelBiotechnology
CompanyMarket capTKN rank
ACTUActuate Therapeutics, Inc.$25.7M
31
QNTMQuantum BioPharma Ltd.$25.9M
41
NNVCNanoViricides, Inc.$25.9M
58
CVMCEL-SCI Corp.$26.0M
35
PLRZPolyrizon Ltd.$26.2M
12
ATOSAtossa Therapeutics, Inc.$25.0M
24
TVRDTvardi Therapeutics, Inc.$24.9M
29

Look up any of the roughly 4,600 stocks we score.

The rank is the raw material. Whether the rules would actually own Actuate Therapeutics, Inc. — and when they’d sell — is the membership. See the Ticker Nerd 20 →

News

Latest ACTU news & analysis

Actuate to Present at the H.C. Wainwright 28th Annual Global Investment Conference

GlobeNewsWire · 9 Sept 2026neutral

Actuate Therapeutics announced it will present at the H.C. Wainwright 28th Annual Global Investment Conference, taking place September 14-16, 2026, in New York City. The management team will also be available for one-on-one meetings during the conference.

Why it matters — An ACTU watcher would care because the presentation offers an opportunity for the company's management to communicate its clinical-stage cancer therapy development to investors at a notable industry conference.

Actuate Announces Promising Preclinical Data Showing Synergistic Activity of Elraglusib in Combination with RAS Inhibitors Zoldonrasib and Daraxonrasib

GlobeNewsWire · 9 Sept 2026positive

Actuate Therapeutics announced new preclinical data showing synergistic activity of elraglusib in combination with the investigational RAS inhibitors zoldonrasib and daraxonrasib in pancreatic ductal adenocarcinoma, including models resistant to FOLFIRINOX chemotherapy. The studies were conducted in collaboration with investigators at Northwestern University and the Mayo Clinic.

Why it matters — The promising preclinical results may support further development of elraglusib combination therapy for difficult-to-treat pancreatic cancer.

All You Need to Know About Actuate Therapeutics, Inc. (ACTU) Rating Upgrade to Buy

Zacks Investment Research · 2 Sept 2026positive

Zacks Investment Research upgraded Actuate Therapeutics, Inc. (ACTU) to a Zacks Rank #2 (Buy), citing growing optimism about the company's earnings prospects, which the report suggests could drive the stock higher in the near term.

Why it matters — The upgrade signals a more favorable analyst view of ACTU's earnings outlook and could influence how investors assess the stock's near-term prospects.

FAQ

Frequently asked questions about ACTU stock

What is the ACTU stock price forecast for 2026-2027?

The 3 Wall Street analysts covering Actuate Therapeutics, Inc. have a median 12-month price target of $12, with estimates ranging from $8 to $15. These are third-party analyst estimates, not Ticker Nerd forecasts, and they are frequently wrong.

Is ACTU stock a buy right now?

Of the 3 analysts covering Actuate Therapeutics, Inc., 3 rate it a Buy, 0 a Hold and 0 a Sell. Ticker Nerd's systematic factor model ranks Actuate Therapeutics, Inc. 31 out of 100 across roughly 4,600 US stocks as at 12 Sept 2026. None of this is personal advice — it does not consider your circumstances.

How does Ticker Nerd's model rank ACTU?

As at 12 Sept 2026, Actuate Therapeutics, Inc. ranks 31 out of 100 on Ticker Nerd's systematic factor model — a percentile across roughly 4,600 US stocks, built from its factor families. Its strongest factor family is Size (87 of 100).

Will ACTU stock go up?

No one can know that. What the data says: the median 12-month target from 3 analysts implies +1021.5% from the last close, and Ticker Nerd's factor model ranks Actuate Therapeutics, Inc. 31 out of 100 as at 12 Sept 2026. Analyst targets are third-party estimates and frequently wrong; none of this is personal advice.

What is the ACTU stock forecast for 2030?

No analyst covering Actuate Therapeutics, Inc. publishes a 2030 price target — Wall Street targets run 12 to 18 months out. Sites quoting a 2030 price for ACTU are extrapolating price history, which says nothing about the business. The furthest attributed numbers are the current analyst targets: $8 to $15 over the next 12 months.

How has ACTU stock performed over the past year?

Actuate Therapeutics, Inc. returned -84.6% over the 12 months to 11 Sept 2026, with dividends reinvested. Past performance does not indicate future returns.

What does Actuate Therapeutics, Inc. do?

Actuate Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for difficult-to-treat cancers.

What is the latest news on ACTU?

The most recent item we track (GlobeNewsWire, 9 Sept 2026): "Actuate to Present at the H.C. Wainwright 28th Annual Global Investment Conference". Actuate Therapeutics announced it will present at the H.C. Wainwright 28th Annual Global Investment Conference, taking place September 14-16, 2026, in New York City. The management team will also be available for one-on-one meetings during the conference.

Company

About Actuate Therapeutics, Inc.

Actuate Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for difficult-to-treat cancers. Its lead program centers on elraglusib, a small-molecule GSK-3 inhibitor being studied in clinical trials for advanced solid tumors and certain pediatric cancers. The company’s work is aimed at targeting cancer pathways involved in tumor growth, survival, and resistance to standard treatments. Actuate Therapeutics also explores applications in cancer types and related disease areas where conventional options remain limited, positioning it within the oncology drug development segment of the healthcare market. Headquartered in Fort Worth, Texas, Actuate Therapeutics concentrates on advancing investigational medicines through early and mid-stage development, with a business model built around translational research, clinical testing, and potential future commercialization of targeted therapies.

CEO Mr. Daniel M. Schmitt · 12 employees · United States · https://actuatetherapeutics.com