APREAPREHealthcare · Biotechnology

APRE Stock Forecast: Aprea Therapeutics, Inc. Price Predictions for 2026-2027

Last close, 21 Aug 2026
$0.64
+0.41% on the day

The 4 Wall Street analysts covering Aprea Therapeutics, Inc. hold a median 12-month price target of $4 — +522.5% from the last close. Ticker Nerd's systematic factor model, run across ~4,600 US stocks, ranks it 44 of 100 as at 22 Aug 2026 — in the lower half.

Market cap
$8.1M
Ticker Nerd rank
44 / 100
Median analyst target
$4.00
Analysts covering
4
Total return, dividends reinvested
1W
−5.5%
1M
−1.4%
YTD
−24.7%
1Y
−59.8%
From 52W high
−61.1%
From 52W low
+8.9%
$0.59
$1.65
52-week range, adjusted closes · the dot is the last close
Ticker Nerd rank

APRE stock analysis: one number for the whole business

Consensus tells you what everyone already believes. The model scores Aprea Therapeutics, Inc. on its factor families — the same systematic rank behind the Ticker Nerd portfolio.

Where the model ranks itAs at 22 Aug 2026
44 / 100

Percentile across ~4,600 US stocks on Ticker Nerd’s systematic factor model. Higher is better. How the model is built and tested

Size
94
Growth
84
Revisions
69
Quality
54
Volatility
37
Accruals
33
Issuance
28
Momentum
23
Value
8

Size (94): Smaller than most of the companies we track.

Value (8): The shares cost a lot relative to the profits and assets behind them.

Built and run by Aslam Ghouse, an ex-Goldman Sachs quant trader with fourteen years in markets.

Wall Street

APRE stock forecast 2026-2027: analyst price targets & predictions

The bullish and bearish analyst opinions on APRE, reported as data — targets and ratings, the market's view beside the model's.

Share price and the analyst range, 12 monthsAdjusted close, US dollars
$0.00$1.00$2.00$3.00$4.00$5.00Oct 25Jan 26Apr 26Jul 26APREHigh $5.00Median $4.00Low $1.20

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

What Wall Street says4 analysts
4 Buy0 Hold0 Sell
Low $1.20Median $4.00High $5.00

The green dot is the last close — the median target sits +522.5% from it.

Recent analyst actionsNewest first
DateFirmActionRatingTarget
13 Aug 2026WedbushMaintainsOutperform$6.00$3.00
14 May 2026WedbushMaintainsOutperform$7.00$6.00
14 May 2026WedbushMaintainsOutperform
7 May 2026OppenheimerInitiatesOutperform$5.00
7 May 2026OppenheimerInitiatesOutperform
31 Mar 2026HC Wainwright & Co.MaintainsBuy
31 Mar 2026WedbushReiteratesOutperform
10 Feb 2026WedbushMaintainsOutperform
29 Jan 2026HC Wainwright & Co.MaintainsBuy
18 Dec 2025HC Wainwright & Co.MaintainsBuy
15 Jan 2025HC Wainwright & Co.ReiteratesBuy
17 Dec 2024HC Wainwright & Co.ReiteratesBuy
18 Nov 2024HC Wainwright & Co.ReiteratesBuy
24 Oct 2024HC Wainwright & Co.ReiteratesBuy
13 Aug 2024WedbushReiteratesOutperform
12 Aug 2024HC Wainwright & Co.ReiteratesBuy
24 June 2024HC Wainwright & Co.ReiteratesBuy
17 June 2024HC Wainwright & Co.ReiteratesBuy
14 May 2024HC Wainwright & Co.ReiteratesBuy
27 Mar 2024WedbushMaintainsOutperform

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Market Radar

This page is one stock. Monday covers all of them.

Computed off the Friday close and sent before the US open.

Market Radar reports the week’s largest rank changes across roughly 4,600 US stocks, the factor behind each one, and where the market went. APRE appears on the weeks it earns a place.

Free, every Monday. Unsubscribe any time.

Estimates

APRE analyst estimate revisions

Not the forecast itself — the direction analysts are revising it. Revision direction is one of the model's factor families.

Which way the estimates are movingNext fiscal year
Analysts raising
1
Analysts cutting
0
Fundamentals

Aprea Therapeutics, Inc. (APRE) financial data

A margin means little on its own. Each bar marks where the figure sits across the whole US universe we score.

Valuation
Trailing P/E
0.5×

Cheaper than 72% of US stocks

Price / sales
1554.9×

Cheaper than 1% of US stocks

Price / book
0.2×

Cheaper than 89% of US stocks

EV / EBITDA
2.5×

Cheaper than 56% of US stocks

Growth & margins
Revenue growth (YoY)
Earnings growth (YoY)
Gross margin
Operating margin
−255025.5%

Higher than 1% of US stocks

Net margin
0.0%

Higher than 30% of US stocks

Returns & dividend
Return on equity
−46.1%

Higher than 22% of US stocks

Return on assets
−27.7%

Higher than 15% of US stocks

Dividend yield

Bars mark the percentile across the ~4,600 US stocks Ticker Nerd covers, among those reporting the figure.

Peers

APRE vs competitors

The nearest names by industry and size, scored by the same model — like for like.

Its peer group, ranked by the same modelBiotechnology
CompanyMarket capTKN rank
APREAprea Therapeutics, Inc.$8.1M
44
ERNAErnexa Therapeutics, Inc.$7.9M
34
AIMAIM ImmunoTech, Inc.$7.9M
20
TRAWTraws Pharma, Inc.$8.0M
48
AZTRAzitra, Inc.$8.0M
28
ACXPAcurx Pharmaceuticals, Inc.$7.7M
24
XBIOXenetic Biosciences, Inc.$8.2M
39

Look up any of the roughly 4,600 stocks we score.

The rank is the raw material. Whether the rules would actually own Aprea Therapeutics, Inc. — and when they’d sell — is the membership. See the Ticker Nerd 20 →

News

Latest APRE news & analysis

Aprea Therapeutics Announces Second Quarter 2026 Financial Results

GlobeNewsWire · 12 Aug 2026positive

Aprea Therapeutics announced its second quarter 2026 financial results. The company reported that enrollment in the ongoing Phase 1 dose escalation ACESOT-1051 trial of oral WEE1 inhibitor APR-1051 is accelerating as dose escalation advances.

Why it matters — APRE watchers would care because accelerating enrollment signals continued momentum for the company's lead clinical program, APR-1051.

Aprea Therapeutics Provides ACESOT-1051 Program Update for WEE1 Inhibitor APR-1051: Accelerating and Expanding Enrollment. Clinical Data Presentation Planned for Q4 2026

GlobeNewsWire · 30 July 2026positive

Aprea Therapeutics provided an update on the ongoing Phase 1 dose escalation ACESOT-1051 trial of its WEE1 inhibitor APR-1051, reporting accelerating enrollment and plans to expand the drug's evaluation into uterine serous carcinoma, platinum-resistant ovarian cancer, HPV-positive head and neck cancer, and colorectal cancer. The company anticipates presenting the next clinical data update at a medical meeting in Q4 2026.

Why it matters — APRE watchers would care because the company is signaling continued clinical progress and an expanded development strategy for APR-1051, its lead pipeline candidate, with a key data catalyst expected in late 2026.

FAQ

Frequently asked questions about APRE stock

What is the APRE stock price forecast for 2026-2027?

The 4 Wall Street analysts covering Aprea Therapeutics, Inc. have a median 12-month price target of $4, with estimates ranging from $1.2 to $5. These are third-party analyst estimates, not Ticker Nerd forecasts, and they are frequently wrong.

Is APRE stock a buy right now?

Of the 4 analysts covering Aprea Therapeutics, Inc., 4 rate it a Buy, 0 a Hold and 0 a Sell. Ticker Nerd's systematic factor model ranks Aprea Therapeutics, Inc. 44 out of 100 across roughly 4,600 US stocks as at 22 Aug 2026. None of this is personal advice — it does not consider your circumstances.

How does Ticker Nerd's model rank APRE?

As at 22 Aug 2026, Aprea Therapeutics, Inc. ranks 44 out of 100 on Ticker Nerd's systematic factor model — a percentile across roughly 4,600 US stocks, built from its factor families. Its strongest factor family is Size (94 of 100).

Will APRE stock go up?

No one can know that. What the data says: the median 12-month target from 4 analysts implies +522.5% from the last close, and Ticker Nerd's factor model ranks Aprea Therapeutics, Inc. 44 out of 100 as at 22 Aug 2026. Analyst targets are third-party estimates and frequently wrong; none of this is personal advice.

What is the APRE stock forecast for 2030?

No analyst covering Aprea Therapeutics, Inc. publishes a 2030 price target — Wall Street targets run 12 to 18 months out. Sites quoting a 2030 price for APRE are extrapolating price history, which says nothing about the business. The furthest attributed numbers are the current analyst targets: $1.2 to $5 over the next 12 months.

How has APRE stock performed over the past year?

Aprea Therapeutics, Inc. returned -59.8% over the 12 months to 21 Aug 2026, with dividends reinvested. Past performance does not indicate future returns.

What does Aprea Therapeutics, Inc. do?

Clear Creek Independent School District is an award-winning pre-K through 12th-grade public school district serving the Greater Houston area in Texas. It provides foundational education to approximately 38,000 students across 100 square miles spanning 13 municipalities in Harris and Galveston counties, making it the 29th largest district in Texas.

What is the latest news on APRE?

The most recent item we track (GlobeNewsWire, 12 Aug 2026): "Aprea Therapeutics Announces Second Quarter 2026 Financial Results". Aprea Therapeutics announced its second quarter 2026 financial results. The company reported that enrollment in the ongoing Phase 1 dose escalation ACESOT-1051 trial of oral WEE1 inhibitor APR-1051 is accelerating as dose escalation advances.

Company

About Aprea Therapeutics, Inc.

Clear Creek Independent School District is an award-winning pre-K through 12th-grade public school district serving the Greater Houston area in Texas. It provides foundational education to approximately 38,000 students across 100 square miles spanning 13 municipalities in Harris and Galveston counties, making it the 29th largest district in Texas. The district operates multiple high schools, including Clear Brook, Clear Creek, Clear Falls, Clear Lake, Clear Springs, and Clear View, alongside elementary and intermediate schools, with a focus on academic excellence, specialized programs, and partnerships with local businesses and higher education institutions to enhance learning experiences. Special services support each student's unique talents and interests, fostering personal success. Financial services manage budgeting, payroll, taxes, cash investments, purchasing, and contract administration to sustain educational operations. The district maintains a balanced general fund budget and reports key financial data, including unclaimed property, ensuring transparency for stakeholders. Headquartered in League City, Texas, Clear Creek Independent School District emphasizes a spirit of exploration and community desirability for families.

CEO Dr. Oren Gilad Ph.D. · 8 employees · United States · https://aprea.com