DFTXHealthcare · Biotechnology

DFTX Stock Forecast: Definium Therapeutics, Inc. Price Predictions for 2026-2027

Last close, 11 Sept 2026
$39
+3.07% on the day

The 18 Wall Street analysts covering Definium Therapeutics, Inc. hold a median 12-month price target of $66 — +69.7% from the last close. Ticker Nerd's systematic factor model, run across ~4,600 US stocks, ranks it 40 of 100 as at 12 Sept 2026 — in the lower half.

Market cap
$5.2B
Ticker Nerd rank
40 / 100
Median analyst target
$66
Analysts covering
18
Revenue$0.0
Operating income−$75.1M
Net income−$159.0M
Free cash flow−$52.8M
Quarterly, 8 quarters to 30 June 2026 · latest quarter's figure shown
Total return, dividends reinvested
1W
+2.3%
1M
−4.9%
YTD
+190.4%
1Y
+303.0%
From 52W high
−19.7%
From 52W low
+330.2%
$9
$48
52-week range, adjusted closes · the dot is the last close
Ticker Nerd rank

DFTX stock analysis: one number for the whole business

Consensus tells you what everyone already believes. The model scores Definium Therapeutics, Inc. on its factor families — the same systematic rank behind the Ticker Nerd portfolio.

Where the model ranks itAs at 12 Sept 2026
40 / 100

Percentile across ~4,600 US stocks on Ticker Nerd’s systematic factor model. Higher is better. How the model is built and tested

Momentum
98
Value
68
Volatility
60
Accruals
59
Quality
48
Issuance
36
Revisions
29
Growth
25
Size
23

Momentum (98): The shares have been drifting up relative to others.

Growth (25): Sales and profits are flat, shrinking, or growing more slowly than they were.

Size (23): Larger than most of the companies we track — more scrutinised, less often mispriced.

Built and run by Aslam Ghouse, an ex-Goldman Sachs quant trader with fourteen years in markets.

Wall Street

DFTX stock forecast 2026-2027: analyst price targets & predictions

The bullish and bearish analyst opinions on DFTX, reported as data — targets and ratings, the market's view beside the model's.

Share price and the analyst range, 12 monthsAdjusted close, US dollars
$0$20$40$60$80$100Oct 25Jan 26Apr 26Jul 26DFTXHigh $90Median $66Low $52

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Data provided by Twelve Data

What Wall Street says18 analysts
18 Buy0 Hold0 Sell
Low $52Median $66High $90

The green dot is the last close — the median target sits +69.7% from it.

Recent analyst actionsNewest first

Of the 20 most recent actions, 7 moved their price target up and 0 moved it down.

DateFirmActionRatingTarget
11 Sept 2026RBC CapitalReiteratesOutperform$66
18 Aug 2026B of A SecuritiesInitiatesBuy$75
18 Aug 2026B of A SecuritiesInitiatesBuy
14 Aug 2026Maxim GroupMaintainsBuy
13 Aug 2026BairdMaintainsOutperform
13 Aug 2026BairdMaintainsOutperform$57$75
13 Aug 2026Canaccord GenuityMaintainsBuy$58$64
13 Aug 2026Canaccord GenuityMaintainsBuy
13 Aug 2026Jones TradingMaintainsBuy$74$90
13 Aug 2026Jones TradingMaintainsBuy
13 Aug 2026RBC CapitalMaintainsOutperform
13 Aug 2026RBC CapitalMaintainsOutperform$57$66
13 Aug 2026Wells FargoMaintainsOverweight
13 Aug 2026Wells FargoMaintainsOverweight$68$72
12 Aug 2026NeedhamMaintainsBuy
12 Aug 2026NeedhamMaintainsBuy$50$66
7 Aug 2026Piper SandlerReiteratesOverweight
7 Aug 2026Piper SandlerReiteratesOverweight$73$75
27 July 2026Wells FargoInitiatesOverweight$68
27 July 2026Wells FargoInitiatesOverweight

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Market Radar

This page is one stock. Monday covers all of them.

Computed off the Friday close and sent before the US open.

Market Radar reports the week’s largest rank changes across roughly 4,600 US stocks, the factor behind each one, and where the market went. DFTX appears on the weeks it earns a place.

Free, every Monday. Unsubscribe any time.

Performance

DFTX vs the S&P 500

Both lines are total return — dividends reinvested — so the comparison is honest on both sides.

Over the twelve months to 11 Sept 2026, Definium Therapeutics, Inc. returned +303.0% against +17.5% for the S&P 500, dividends included.

DFTX vs S&P 500, last 12 monthsTotal return, rebased to 100
100200300400500Oct 25Jan 26Apr 26Jul 26DFTXS&P 500

Download this chart as an image — free to reuse; link this page as the source.

Data provided by Twelve Data

Estimates

DFTX analyst estimate revisions

Not the forecast itself — the direction analysts are revising it. Revision direction is one of the model's factor families.

Which way the estimates are movingNext fiscal year
Analysts raising
0
Analysts cutting
12
Fundamentals

Definium Therapeutics, Inc. (DFTX) financial data

A margin means little on its own. Each bar marks where the figure sits across the whole US universe we score.

Valuation
Trailing P/E
−18.9×

Cheaper than 96% of US stocks

Price / sales
Price / book
5.7×

Cheaper than 18% of US stocks

EV / EBITDA
−26.9×

Cheaper than 91% of US stocks

Growth & margins
Revenue growth (YoY)
Earnings growth (YoY)
Gross margin
Operating margin
0.0%

Higher than 32% of US stocks

Net margin
0.0%

Higher than 30% of US stocks

Returns & dividend
Return on equity
−64.1%

Higher than 18% of US stocks

Return on assets
−20.6%

Higher than 19% of US stocks

Dividend yield

Bars mark the percentile across the ~4,600 US stocks Ticker Nerd covers, among those reporting the figure.

Key statistics

Definium Therapeutics, Inc. (DFTX) statistics: revenue, profit & scale

The headline figures, each with its date. Every row carries its own link — cite it straight from here.

  • Definium Therapeutics, Inc. has a market value of $5.2B and an enterprise value of $4.2B.

  • Revenue in the twelve months to 30 June 2026: $0.0.

  • Net income over the same four quarters: −$353.8M.

  • Free cash flow in the twelve months to 30 June 2026: −$168.0M.

  • Shares outstanding: 132.7M.

  • Trailing P/E: −18.9×; forward P/E: −20.7× — the forward figure prices analyst consensus estimates, not reported earnings.

  • Definium Therapeutics, Inc. employs 105 people.

Statement figures: company filings via Twelve Data, four quarters to 30 June 2026 · market figures as at 14 Sept 2026

Data provided by Twelve Data

Peers

DFTX vs competitors

The nearest names by industry and size, scored by the same model — like for like.

Its peer group, ranked by the same modelBiotechnology
CompanyMarket capTKN rank
DFTXDefinium Therapeutics, Inc.$5.2B
40
CRSPCRISPR Therapeutics AG$5.0B
36
ACADACADIA Pharmaceuticals, Inc.$4.8B
81
EWTXEdgewise Therapeutics, Inc.$4.8B
51
ERASErasca, Inc.$5.4B
55
PTCTPTC Therapeutics, Inc.$5.5B
65
XENEXenon Pharmaceuticals, Inc.$5.6B
50

Look up any of the roughly 4,600 stocks we score.

The rank is the raw material. Whether the rules would actually own Definium Therapeutics, Inc. — and when they’d sell — is the membership. See the Ticker Nerd 20 →

News

Latest DFTX news & analysis

Definium Says Its Anxiety Drug Showed 'Unprecedented Efficacy'

Benzinga · 14 Sept 2026positive

Definium Therapeutics released topline results from Panorama, its second Phase 3 study of DT120 (lysergide) Orally Disintegrating Tablet in adults with generalized anxiety disorder, describing the efficacy as "unprecedented."

Why it matters — A favorable reading from this Phase 3 trial could be an important step in the development of DFTX's lead anxiety drug candidate.

Definium Therapeutics Announces Positive Topline Results from Phase 3 Panorama Study of DT120 ODT in Generalized Anxiety Disorder

Business Wire · 14 Sept 2026positive

Definium Therapeutics announced positive topline results from Panorama, its second Phase 3 study of DT120 (lysergide) Orally Disintegrating Tablet (ODT) in adults with generalized anxiety disorder (GAD). This marks the company's third late-stage study of the candidate.

Why it matters — A positive second Phase 3 readout represents a significant late-stage clinical milestone for DFTX's lead candidate DT120 in generalized anxiety disorder.

Definium Therapeutics Announces New Employee Inducement Grants

Business Wire · 14 Sept 2026neutral

Definium Therapeutics announced inducement grants to three newly hired non-executive employees, consisting of options to purchase an aggregate of 56,650 common shares with effective grant dates of September 14.

Why it matters — The grants signal new employee hiring but involve option issuance that could represent share dilution for existing holders.

Definium Therapeutics to Present Topline Data from Phase 3 Emerge and Voyage Trials Across Major Depressive Disorder and Generalized Anxiety Disorder at Psych Congress 2026

Business Wire · 10 Sept 2026positive

Definium Therapeutics announced it will present six poster presentations at Psych Congress 2026 in New Orleans, including topline data from its Phase 3 Emerge and Voyage trials across major depressive disorder and generalized anxiety disorder, as well as findings from its DT120 Orally Disintegrating Tablet Phase 3 clinical program.

Why it matters — DFTX watchers would care because the planned presentations of Phase 3 topline data represent a major clinical milestone for the company's lead psychiatric programs.

Definium Therapeutics Receives Breakthrough Therapy Designation for DT120 (lysergide) Orally Disintegrating Tablet (ODT) in Major Depressive Disorder (MDD) Following Positive Phase 3 Results

Business Wire · 8 Sept 2026positive

Definium Therapeutics announced that the U.S. FDA has granted Breakthrough Therapy designation for its investigational drug DT120 (lysergide) orally disintegrating tablet for major depressive disorder. The designation was supported by significant unmet medical need in MDD and results from the Company.

Why it matters — FDA Breakthrough Therapy designation could accelerate development and review of DT120 in MDD, a key pipeline asset for the company.

FAQ

Frequently asked questions about DFTX stock

What is the DFTX stock price forecast for 2026-2027?

The 18 Wall Street analysts covering Definium Therapeutics, Inc. have a median 12-month price target of $66, with estimates ranging from $52 to $90. These are third-party analyst estimates, not Ticker Nerd forecasts, and they are frequently wrong.

Is DFTX stock a buy right now?

Of the 18 analysts covering Definium Therapeutics, Inc., 18 rate it a Buy, 0 a Hold and 0 a Sell. Ticker Nerd's systematic factor model ranks Definium Therapeutics, Inc. 40 out of 100 across roughly 4,600 US stocks as at 12 Sept 2026. None of this is personal advice — it does not consider your circumstances.

How does Ticker Nerd's model rank DFTX?

As at 12 Sept 2026, Definium Therapeutics, Inc. ranks 40 out of 100 on Ticker Nerd's systematic factor model — a percentile across roughly 4,600 US stocks, built from its factor families. Its strongest factor family is Momentum (98 of 100).

Will DFTX stock go up?

No one can know that. What the data says: the median 12-month target from 18 analysts implies +69.7% from the last close, and Ticker Nerd's factor model ranks Definium Therapeutics, Inc. 40 out of 100 as at 12 Sept 2026. Analyst targets are third-party estimates and frequently wrong; none of this is personal advice.

What is the DFTX stock forecast for 2030?

No analyst covering Definium Therapeutics, Inc. publishes a 2030 price target — Wall Street targets run 12 to 18 months out. Sites quoting a 2030 price for DFTX are extrapolating price history, which says nothing about the business. The furthest attributed numbers are the current analyst targets: $52 to $90 over the next 12 months.

How has DFTX stock performed over the past year?

Definium Therapeutics, Inc. returned +303.0% over the 12 months to 11 Sept 2026, with dividends reinvested. Past performance does not indicate future returns.

What does Definium Therapeutics, Inc. do?

Definium Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on developing novel treatments for brain health disorders.

What is the latest news on DFTX?

The most recent item we track (Benzinga, 14 Sept 2026): "Definium Says Its Anxiety Drug Showed 'Unprecedented Efficacy'". Definium Therapeutics released topline results from Panorama, its second Phase 3 study of DT120 (lysergide) Orally Disintegrating Tablet in adults with generalized anxiety disorder, describing the efficacy as "unprecedented."

Company

About Definium Therapeutics, Inc.

Definium Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on developing novel treatments for brain health disorders. The company’s current pipeline centers on psychiatry and neurology, with lead product candidates such as DT120, an orally disintegrating tablet under late-stage study for generalized anxiety disorder and major depressive disorder, and DT402, which is being evaluated for autism spectrum disorder. Definium Therapeutics applies a research-driven approach to psychedelic-derived and other brain-health-focused therapeutics, aiming to address underlying causes of psychiatric and neurological conditions. The company operates from New York and serves the healthcare and biotechnology markets through its drug development programs and clinical research activities.

CEO Mr. Robert Barrow · 105 employees · United States · https://definiumtx.com