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FULC Stock Forecast: Fulcrum Therapeutics, Inc. Price Predictions for 2026-2027

Last close, 11 Sept 2026
$3.80
0.00% on the day

The 6 Wall Street analysts covering Fulcrum Therapeutics, Inc. hold a median 12-month price target of $3.5 — -7.9% from the last close. Ticker Nerd's systematic factor model, run across ~4,600 US stocks, ranks it 36 of 100 as at 12 Sept 2026 — in the lower half.

Market cap
$289.9M
Ticker Nerd rank
36 / 100
Median analyst target
$3.50
Analysts covering
6
Revenue$0.0
Operating income−$19.9M
Net income−$26.2M
Free cash flow−$16.1M
Quarterly, 8 quarters to 30 June 2026 · latest quarter's figure shown
Total return, dividends reinvested
1W
−1.0%
1M
+3.0%
YTD
−66.4%
1Y
−45.6%
From 52W high
−74.0%
From 52W low
+21.0%
$3
$15
52-week range, adjusted closes · the dot is the last close
Ticker Nerd rank

FULC stock analysis: one number for the whole business

Consensus tells you what everyone already believes. The model scores Fulcrum Therapeutics, Inc. on its factor families — the same systematic rank behind the Ticker Nerd portfolio.

Where the model ranks itAs at 12 Sept 2026
36 / 100

Percentile across ~4,600 US stocks on Ticker Nerd’s systematic factor model. Higher is better. How the model is built and tested

Quality
65
Size
62
Accruals
59
Growth
58
Revisions
48
Issuance
48
Volatility
34
Momentum
21
Value
13

Quality (65): The business earns solid, repeatable profits on what it owns.

Value (13): The shares cost a lot relative to the profits and assets behind them.

Built and run by Aslam Ghouse, an ex-Goldman Sachs quant trader with fourteen years in markets.

Wall Street

FULC stock forecast 2026-2027: analyst price targets & predictions

The bullish and bearish analyst opinions on FULC, reported as data — targets and ratings, the market's view beside the model's.

Share price and the analyst range, 12 monthsAdjusted close, US dollars
$2$4$6$8$10$12$14Oct 25Jan 26Apr 26Jul 26FULCHigh $4.00Median $3.50Low $3.00

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Data provided by Twelve Data

What Wall Street says6 analysts
0 Buy5 Hold1 Sell
Low $3.00Median $3.50High $4.00

The green dot is the last close — the median target sits −7.9% from it.

Recent analyst actionsNewest first

Of the 20 most recent actions, 0 moved their price target up and 5 moved it down.

DateFirmActionRatingTarget
3 June 2026JP MorganDowngradeUnderweight—
2 June 2026HC Wainwright & Co.DowngradeNeutral$25 → $3.00
2 June 2026Leerink PartnersDowngradeMarket Perform$24 → $4.00
2 June 2026Piper SandlerDowngradeUnderweight$23 → $3.00
2 June 2026StifelDowngradeHold$25 → $3.00
2 June 2026Truist SecuritiesDowngradeHold$17 → $4.00
12 Jan 2026JP MorganInitiatesOverweight—
11 Dec 2025Truist SecuritiesMaintainsBuy—
9 Dec 2025B of A SecuritiesMaintainsUnderperform—
8 Dec 2025Cantor FitzgeraldMaintainsOverweight—
8 Dec 2025HC Wainwright & Co.MaintainsBuy—
8 Dec 2025Piper SandlerReiteratesOverweight—
8 Dec 2025RBC CapitalMaintainsSector Perform—
24 Nov 2025HC Wainwright & Co.MaintainsBuy—
24 Nov 2025Truist SecuritiesInitiatesBuy—
30 Oct 2025Piper SandlerReiteratesOverweight—
30 Oct 2025RBC CapitalMaintainsSector Perform—
20 Oct 2025HC Wainwright & Co.ReiteratesBuy—
30 July 2025RBC CapitalMaintainsSector Perform—
29 July 2025HC Wainwright & Co.UpgradeBuy—

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Market Radar

This page is one stock. Monday covers all of them.

Computed off the Friday close and sent before the US open.

Market Radar reports the week’s largest rank changes across roughly 4,600 US stocks, the factor behind each one, and where the market went. FULC appears on the weeks it earns a place.

Free, every Monday. Unsubscribe any time.

Performance

FULC vs the S&P 500

Both lines are total return — dividends reinvested — so the comparison is honest on both sides.

Over the twelve months to 11 Sept 2026, Fulcrum Therapeutics, Inc. returned −45.6% against +17.5% for the S&P 500, dividends included.

FULC vs S&P 500, last 12 monthsTotal return, rebased to 100
50100150200Oct 25Jan 26Apr 26Jul 26FULCS&P 500

Download this chart as an image — free to reuse; link this page as the source.

Data provided by Twelve Data

Estimates

FULC analyst estimate revisions

Not the forecast itself — the direction analysts are revising it. Revision direction is one of the model's factor families.

Which way the estimates are movingNext fiscal year
Analysts raising
1
Analysts cutting
1
Fundamentals

Fulcrum Therapeutics, Inc. (FULC) financial data

A margin means little on its own. Each bar marks where the figure sits across the whole US universe we score.

Valuation
Trailing P/E
−3.2×

Cheaper than 87% of US stocks

Price / sales
—
Price / book
0.9×

Cheaper than 75% of US stocks

EV / EBITDA
0.3×

Cheaper than 59% of US stocks

Growth & margins
Revenue growth (YoY)
—
Earnings growth (YoY)
—
Gross margin
—
Operating margin
0.0%

Higher than 32% of US stocks

Net margin
0.0%

Higher than 30% of US stocks

Returns & dividend
Return on equity
−32.4%

Higher than 26% of US stocks

Return on assets
−19.6%

Higher than 20% of US stocks

Dividend yield
—

Bars mark the percentile across the ~4,600 US stocks Ticker Nerd covers, among those reporting the figure.

Key statistics

Fulcrum Therapeutics, Inc. (FULC) statistics: revenue, profit & scale

The headline figures, each with its date. Every row carries its own link — cite it straight from here.

  • Fulcrum Therapeutics, Inc. has a market value of $289.9M and an enterprise value of −$23.6M.

  • Revenue in the twelve months to 30 June 2026: $0.0.

  • Net income over the same four quarters: −$85.0M.

  • Diluted earnings per share, trailing twelve months: $−1.21.

  • Free cash flow in the twelve months to 30 June 2026: −$66.1M.

  • Shares outstanding: 76.3M.

  • Trailing P/E: −3.2×; forward P/E: −7.8× — the forward figure prices analyst consensus estimates, not reported earnings.

  • Fulcrum Therapeutics, Inc. employs 9 people.

Statement figures: company filings via Twelve Data, four quarters to 30 June 2026 · market figures as at 13 Sept 2026

Data provided by Twelve Data

Peers

FULC vs competitors

The nearest names by industry and size, scored by the same model — like for like.

Its peer group, ranked by the same modelBiotechnology
CompanyMarket capTKN rank
FULCFulcrum Therapeutics, Inc.$289.9M
36
LYELLyell Immunopharma, Inc.$293.1M
63
YDESYD Bio Ltd.$283.4M
3
VNDAVanda Pharmaceuticals, Inc.$300.9M
44
STROSutro Biopharma, Inc.$276.3M
73
IMRXImmuneering Corp.$275.7M
47
ACIUAC Immune SA$273.1M
35

Look up any of the roughly 4,600 stocks we score.

The rank is the raw material. Whether the rules would actually own Fulcrum Therapeutics, Inc. — and when they’d sell — is the membership. See the Ticker Nerd 20 →

News

Latest FULC news & analysis

Kaplan Fox Urges Investors of Fulcrum Therapeutics, Inc. (FULC) with Losses to Contact the Firm

Newsfile Corp · 10 Sept 2026negative

Kaplan Fox & Kilsheimer LLP announced that it is investigating potential securities violations against Fulcrum Therapeutics, Inc. (NASDAQ: FULC). The firm is urging investors who have suffered losses, or who have information relevant to the investigation, to contact them.

Why it matters — FULC watchers would care because the company is now facing a securities-law investigation that could lead to legal or regulatory consequences.

BRODSKY & SMITH SHAREHOLDER UPDATE: Notifying Investors of the Following Investigations: Centerspace (NYSE – CSR), Fulcrum Therapeutics, Inc. (Nasdaq – FULC), Weave Communications, Inc. (NYSE – WEAV), Bio-Techne Corporation (Nasdaq – TECH)

GlobeNewsWire · 9 Sept 2026neutral

Brodsky & Smith issued a shareholder update notifying investors that it is investigating Fulcrum Therapeutics, Inc. (FULC), along with Centerspace, Weave Communications, and Bio-Techne. The firm invites shareholders who wish to discuss the matter to contact it at no cost or financial obligation.

Why it matters — FULC watchers would care because an announced law-firm investigation signals potential shareholder concerns that could warrant monitoring.

Kaplan Fox Reminds Investors of Fulcrum Therapeutics, Inc. (FULC) of an Ongoing Securities Investigation

Newsfile Corp · 9 Sept 2026negative

Kaplan Fox & Kilsheimer LLP announced it is investigating potential securities violations against Fulcrum Therapeutics, Inc. (NASDAQ: FULC). The law firm is inviting Fulcrum investors who have suffered losses or who have relevant information to come forward.

Why it matters — A securities investigation into the company could signal possible legal or disclosure issues that FULC watchers should be aware of.

FULC Stock Alert: Halper Sadeh LLC is Investigating Whether Fulcrum Therapeutics, Inc. is Obtaining a Fair Price for its Shareholders

Business Wire · 5 Sept 2026negative

Halper Sadeh LLC, an investor rights law firm, is investigating the proposed merger of Fulcrum Therapeutics and Slate Medicines, Inc. Upon closing, Fulcrum shareholders are expected to own 5.0% of the combined company. The firm is looking into whether Fulcrum is obtaining a fair price for its shareholders and encouraging shareholders to learn about their rights.

Why it matters — Fulcrum watchers would care because the investigation raises questions about the fairness of the merger terms and the value that Fulcrum shareholders would receive in the combined company.

Kaplan Fox Advises Investors of Fulcrum Therapeutics, Inc. (FULC) to Contact the Firm Regarding a Securities Investigation

Newsfile Corp · 2 Sept 2026negative

Law firm Kaplan Fox & Kilsheimer LLP announced it is investigating potential securities violations against Fulcrum Therapeutics, Inc. (NASDAQ: FULC) and is inviting Fulcrum investors who have suffered losses to contact the firm.

Why it matters — The announcement signals an active securities investigation into the company that Fulcrum Therapeutics investors may want to monitor.

FAQ

Frequently asked questions about FULC stock

What is the FULC stock price forecast for 2026-2027?

The 6 Wall Street analysts covering Fulcrum Therapeutics, Inc. have a median 12-month price target of $3.5, with estimates ranging from $3 to $4. These are third-party analyst estimates, not Ticker Nerd forecasts, and they are frequently wrong.

Is FULC stock a buy right now?

Of the 6 analysts covering Fulcrum Therapeutics, Inc., 0 rate it a Buy, 5 a Hold and 1 a Sell. Ticker Nerd's systematic factor model ranks Fulcrum Therapeutics, Inc. 36 out of 100 across roughly 4,600 US stocks as at 12 Sept 2026. None of this is personal advice — it does not consider your circumstances.

How does Ticker Nerd's model rank FULC?

As at 12 Sept 2026, Fulcrum Therapeutics, Inc. ranks 36 out of 100 on Ticker Nerd's systematic factor model — a percentile across roughly 4,600 US stocks, built from its factor families. Its strongest factor family is Quality (65 of 100).

Will FULC stock go up?

No one can know that. What the data says: the median 12-month target from 6 analysts implies -7.9% from the last close, and Ticker Nerd's factor model ranks Fulcrum Therapeutics, Inc. 36 out of 100 as at 12 Sept 2026. Analyst targets are third-party estimates and frequently wrong; none of this is personal advice.

What is the FULC stock forecast for 2030?

No analyst covering Fulcrum Therapeutics, Inc. publishes a 2030 price target — Wall Street targets run 12 to 18 months out. Sites quoting a 2030 price for FULC are extrapolating price history, which says nothing about the business. The furthest attributed numbers are the current analyst targets: $3 to $4 over the next 12 months.

How has FULC stock performed over the past year?

Fulcrum Therapeutics, Inc. returned -45.6% over the 12 months to 11 Sept 2026, with dividends reinvested. Past performance does not indicate future returns.

What does Fulcrum Therapeutics, Inc. do?

Fulcrum Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing small-molecule therapies for genetically defined rare diseases.

What is the latest news on FULC?

The most recent item we track (Newsfile Corp, 10 Sept 2026): "Kaplan Fox Urges Investors of Fulcrum Therapeutics, Inc. (FULC) with Losses to Contact the Firm". Kaplan Fox & Kilsheimer LLP announced that it is investigating potential securities violations against Fulcrum Therapeutics, Inc. (NASDAQ: FULC). The firm is urging investors who have suffered losses, or who have information relevant to the investigation, to contact them.

Company

About Fulcrum Therapeutics, Inc.

Fulcrum Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing small-molecule therapies for genetically defined rare diseases. The company’s work centers on gene regulation and epigenetic control, using its discovery platform to identify drug targets that may address the root causes of disease rather than only managing symptoms. Its lead clinical program, pociredir, is designed to increase fetal hemoglobin expression and is being studied for sickle cell disease. Fulcrum Therapeutics also advances research programs in other serious hematologic and rare disorders, including beta-thalassemia and inherited aplastic anemias, while maintaining a broader focus on areas of high unmet medical need. Based in Cambridge, Massachusetts, Fulcrum Therapeutics plays a specialized role in the biotechnology market as a developer of precision medicines for challenging diseases with limited treatment options.

CEO Mr. Alexander C. Sapir · 9 employees · United States · https://www.fulcrumtx.com