Johnson & Johnson's RYBREVANT® (amivantamab-vmjw) plus chemotherapy delivers longest reported median overall survival in EGFR exon 20 insertion mutation-positive lung cancer
Johnson & Johnson announced results from the final overall survival analysis of the Phase 3 PAPILLON study, showing that first-line RYBREVANT (amivantamab-vmjw) plus carboplatin-pemetrexed chemotherapy delivered the longest reported median overall survival in patients with advanced non-small cell lung cancer with EGFR exon 20 insertion mutations, compared with chemotherapy alone.
Why it matters — The positive final survival data for RYBREVANT plus chemotherapy could strengthen JNJ's oncology portfolio by addressing a patient population historically facing poor outcomes with a low five-year survival rate.