Graviton BioScience Corporation Announces Publication of Positive Ph1b Trial Results for GV101 (TDI01) in Chronic Graft versus Host Disease in Signal Transduction and Targeted Therapy, by Beijing Tide Pharmaceutical
Graviton BioScience Corporation announced the publication in Signal Transduction and Targeted Therapy of positive Phase 1b trial results for GV101 (TDI01), a selective ROCK2 inhibitor, in chronic Graft versus Host Disease (cGvHD). The therapy showed best overall response rates at 400 mg and 200 mg at 24 weeks in patients who had failed at least two prior lines of therapy, with the 24-week rate exceeding published 6-month rates for approved steroid-refractory cGvHD therapies.
Why it matters — An MGTX watcher would care because this news reflects progress in the competitive therapeutic landscape for cGvHD treatment by a separate biopharmaceutical company.