Milestone Pharmaceuticals Initiates Pivotal Phase 3 Trial of Etripamil Nasal Spray for Self-Administered Treatment of Atrial Fibrillation with Rapid Ventricular Rate (AFib-RVR)
Milestone Pharmaceuticals announced the initiation of its pivotal Phase 3 trial (ReVeRA-301) of etripamil nasal spray for the self-administered treatment of atrial fibrillation with rapid ventricular rate (AFib-RVR). The trial is evaluating the same 70 mg repeat-dose regimen that is FDA approved for paroxysmal supraventricular tachycardia (PSVT).
Why it matters — This advances a new, potentially significant indication for etripamil beyond its approved PSVT use, expanding Milestone's pipeline and commercial opportunity.