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PLRX Stock Forecast: Pliant Therapeutics Inc. Price Predictions for 2027

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$1.12

+0.03 (2.75%)

PLRX Stock Forecast 2026-2027

$1.12
Current Price
$67.49M
Market Cap
5 Ratings
Buy 0
Hold 4
Sell 1
Wall St Analyst Ratings

Distance to PLRX Price Targets

+167.9%
To High Target of $3.00
+123.2%
To Median Target of $2.50
+78.6%
To Low Target of $2.00

PLRX Price Momentum

-0.9%
1 Week Change
-5.9%
1 Month Change
-16.4%
1 Year Change
-8.2%
Year-to-Date Change
-42.6%
From 52W High of $1.95
+3.7%
From 52W Low of $1.08
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Latest PLRX Stock Price Targets & Analyst Predictions

Based on our analysis of 5 Wall Street analysts, PLRX has a neutral consensus with a median price target of $2.50 (ranging from $2.00 to $3.00). The overall analyst rating is Hold (5.6/10). Currently trading at $1.12, the median forecast implies a 123.2% upside. This outlook is supported by 0 Buy, 4 Hold, and 1 Sell ratings.

The most optimistic forecast comes from Edward Nash at Canaccord Genuity, projecting a 167.9% upside.

Please note that analyst price targets are forward-looking estimates subject to substantial market, economic, and company-specific risks. Past performance does not guarantee future results, and actual stock performance may materially differ from these projections. Investors should conduct their own due diligence and consider their investment objectives and risk tolerance before making investment decisions.

PLRX Analyst Ratings

0
Buy
4
Hold
1
Sell

PLRX Price Target Range

Low
$2.00
Average
$2.50
High
$3.00
Current: $1.12

Latest PLRX Stock Forecasts by Analyst

These are the latest 20 analyst ratings and price targets for PLRX.

Date Firm Analyst Rating Change Price Target
Mar 13, 2026 Canaccord Genuity Edward Nash Hold Maintains $3.00
Mar 12, 2026 Piper Sandler Yasmeen Rahimi Overweight Maintains $3.00
Nov 7, 2025 RBC Capital Sector Perform Maintains $N/A
Oct 10, 2025 JP Morgan Underweight Downgrade $N/A
Aug 8, 2025 Piper Sandler Overweight Maintains $N/A
Mar 18, 2025 HC Wainwright & Co. Neutral Reiterates $N/A
Mar 4, 2025 HC Wainwright & Co. Neutral Reiterates $N/A
Mar 4, 2025 Citigroup Neutral Maintains $N/A
Mar 4, 2025 RBC Capital Sector Perform Maintains $N/A
Mar 4, 2025 Wells Fargo Equal-Weight Maintains $N/A
Mar 4, 2025 Needham Hold Downgrade $N/A
Mar 4, 2025 Cantor Fitzgerald Pete Stavropoulos Neutral Reinstates $N/A
Mar 3, 2025 Leerink Partners Market Perform Downgrade $N/A
Feb 14, 2025 HC Wainwright & Co. Neutral Reiterates $N/A
Feb 14, 2025 Needham Buy Reiterates $N/A
Feb 10, 2025 JP Morgan Neutral Downgrade $N/A
Feb 10, 2025 RBC Capital Sector Perform Downgrade $N/A
Feb 10, 2025 Canaccord Genuity Hold Downgrade $N/A
Feb 10, 2025 Wells Fargo Equal-Weight Downgrade $N/A
Feb 10, 2025 Citigroup Neutral Downgrade $N/A

Pliant Therapeutics Inc. (PLRX) Competitors

The following stocks are similar to Pliant based on their market capitalization and industry sector. These similar stocks potentially provide investors with alternative investment opportunities within the same market segment.

Pliant Therapeutics Inc. (PLRX) Financial Data

Pliant Therapeutics Inc. has a market capitalization of $67.49M with a P/E ratio of -0.5x. The company generates $0 in trailing twelve-month revenue with a 0.0% profit margin.

Revenue growth is N/A quarter-over-quarter, while maintaining an operating margin of 0.0% and return on equity of -53.6%.

Valuation Metrics

Market Cap $67.49M
Enterprise Value $-75,128,272
P/E Ratio -0.5x
PEG Ratio 0.0x
Price/Sales N/A

Growth & Margins

Revenue Growth (YoY) N/A
Gross Margin N/A
Operating Margin 0.0%
Net Margin 0.0%
EPS Growth N/A

Financial Health

Cash/Price Ratio +248.3%
Current Ratio 16.9x
Debt/Equity 17.4x
ROE -53.6%
ROA -25.8%
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Pliant Therapeutics Inc. logo

Pliant Therapeutics Inc. (PLRX) Business Model

About Pliant Therapeutics Inc.

What They Do

Develops integrin-based therapeutics for diseases.

Business Model

The company focuses on discovering and developing novel small-molecule inhibitors and monoclonal antibodies that target integrin receptors, aiming to treat fibrotic diseases, solid tumors, and muscular dystrophies. Pliant Therapeutics generates revenue through partnerships, grants, and potential future sales of its drug candidates as they progress through clinical development and gain regulatory approval.

Additional Information

Pliant's pipeline includes promising candidates like bexotegrast, PLN-101095, and PLN-101325, with ongoing clinical trials aimed at addressing significant unmet medical needs. The company employs a proprietary discovery platform to enhance drug delivery and efficacy, positioning itself as a key player in precision therapies within the biotechnology industry. Founded in 2015 and based in South San Francisco, California, Pliant Therapeutics is committed to advancing innovative treatment options.

Company Information

Sector

Healthcare

Industry

Biotechnology

Employees

49

CEO

Dr. Bernard Coulie M.B.A., M.D., Ph.D.

Country

United States

IPO Year

2020

Pliant Therapeutics Inc. (PLRX) Latest News & Analysis

Latest News

PLRX stock latest news image
Quick Summary

Recent appointments enhance the Board's expertise in global oncology drug development, strengthening operational and regulatory capabilities.

Why It Matters

New appointments enhance the board's expertise in oncology, potentially accelerating drug development and improving regulatory navigation, which could lead to increased market competitiveness and investor confidence.

Source: GlobeNewsWire
Market Sentiment: Neutral
PLRX stock latest news image
Quick Summary

Pliant Therapeutics, Inc. (PLRX) presented at the RBC Capital Markets Global Healthcare Conference 2026, sharing insights and updates on their initiatives.

Why It Matters

Pliant Therapeutics' presentation at a major healthcare conference signals potential insights into its pipeline and strategy, influencing investor sentiment and stock performance.

Source: Seeking Alpha
Market Sentiment: Neutral
PLRX stock latest news image
Quick Summary

Pliant Therapeutics (Nasdaq: PLRX) is conducting a Phase 1b trial, FORTIFY, for PLN-101095 targeting ICI-refractory solid tumors. Results will be presented at the ASCO Annual Meeting from May 29 to June 2, 2026.

Why It Matters

Pliant Therapeutics' trial results for PLN-101095 could influence its stock performance, as successful outcomes may attract investment interest and validate its pipeline.

Source: GlobeNewsWire
Market Sentiment: Neutral
PLRX stock latest news image
Quick Summary

The first participant has been dosed in the FORTIFY Phase 1b trial for PLN-101095. Updated data from a Phase 1 trial shows improved responses in checkpoint inhibitor-refractory solid tumors.

Why It Matters

The dosing of the first participant in the FORTIFY trial signals progress for PLN-101095, potentially enhancing its market value and attracting investor interest in oncology advancements.

Source: GlobeNewsWire
Market Sentiment: Neutral
PLRX stock latest news image
Quick Summary

Pliant Therapeutics (Nasdaq: PLRX) will participate in the RBC Capital Markets Global Healthcare Conference on May 19, 2026, featuring CEO Bernard Coulie and CFO Keith Cummings in a fireside chat.

Why It Matters

Pliant Therapeutics' participation in a major healthcare conference highlights its visibility and potential for investor interest, impacting stock performance and market perception.

Source: GlobeNewsWire
Market Sentiment: Neutral
PLRX stock latest news image
Quick Summary

Pliant Therapeutics (Nasdaq: PLRX) has begun dosing in the FORTIFY Phase 1b trial for PLN-101095, targeting ICI-refractory advanced solid tumors in combination with pembrolizumab.

Why It Matters

Pliant Therapeutics' trial results for PLN-101095 could impact its stock value significantly, especially if positive outcomes enhance its market potential in cancer treatment.

Source: GlobeNewsWire
Market Sentiment: Neutral

Frequently Asked Questions About PLRX Stock

What is Pliant Therapeutics Inc.'s (PLRX) stock forecast for 2027?

Based on our analysis of 5 Wall Street analysts, Pliant Therapeutics Inc. (PLRX) has a median price target of $2.50. The highest price target is $3.00 and the lowest is $2.00.

Is PLRX stock a good investment in 2027?

According to current analyst ratings, PLRX has 0 Buy ratings, 4 Hold ratings, and 1 Sell ratings. The stock is currently trading at $1.12. Always conduct your own research and consider your investment goals before making investment decisions.

What is the long-term price prediction for PLRX stock?

Wall Street analysts predict PLRX stock could reach $2.50 in the next 12 months. This represents a 123.2% increase from the current price of $1.12. Please note that this is a projection by Wall Street analysts and not a guarantee.

What is Pliant Therapeutics Inc.'s business model?

The company focuses on discovering and developing novel small-molecule inhibitors and monoclonal antibodies that target integrin receptors, aiming to treat fibrotic diseases, solid tumors, and muscular dystrophies. Pliant Therapeutics generates revenue through partnerships, grants, and potential future sales of its drug candidates as they progress through clinical development and gain regulatory approval.

What is the highest forecasted price for PLRX Pliant Therapeutics Inc.?

The highest price target for PLRX is $3.00 from Edward Nash at Canaccord Genuity, which represents a 167.9% increase from the current price of $1.12.

What is the lowest forecasted price for PLRX Pliant Therapeutics Inc.?

The lowest price target for PLRX is $2.00 from at , which represents a 78.6% increase from the current price of $1.12.

What is the overall PLRX consensus from analysts for Pliant Therapeutics Inc.?

The overall analyst consensus for PLRX is neutral. Out of 5 Wall Street analysts, 0 rate it as Buy, 4 as Hold, and 1 as Sell, with a median price target of $2.50.

How accurate are PLRX stock price projections?

Stock price projections, including those for Pliant Therapeutics Inc., are based on various factors including financial models, market conditions, and analyst forecasts. While these predictions provide valuable insights, they should be considered alongside your own research and risk tolerance.

Important Disclaimer

The information provided by Ticker Nerd is for educational and informational purposes only. It should not be considered financial or investment advice. Past performance is not indicative of future results. Always conduct your own research and consult with a qualified financial advisor before making any investment decisions. Analyst ratings and price forecasts are sourced from Wall St analysts and other experts. These projections are speculative and do not guarantee future stock performance.

Last updated: July 16, 2026 2:55 AM UTC
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