PVLAPVLAHealthcare · Biotechnology

PVLA Stock Forecast: Palvella Therapeutics, Inc. Price Predictions for 2026-2027

Last close, 18 Sept 2026
$151
−2.44% on the day

The 15 Wall Street analysts covering Palvella Therapeutics, Inc. hold a median 12-month price target of $232 — +54.1% from the last close. Ticker Nerd's systematic factor model, run across ~4,600 US stocks, ranks it 32 of 100 as at 18 Sept 2026 — in the lower half. The Street sees upside; the factor read is a caution. That gap is the story on this page.

Market cap
$2.2B
Ticker Nerd rank
32 / 100
Median analyst target
$232
Analysts covering
15
Revenue$0.0
Operating income−$21.4M
Net income−$21.9M
Free cash flow−$12.8M
Quarterly, 8 quarters to 30 June 2026 · latest quarter's figure shown
Total return, dividends reinvested
1W
+0.3%
1M
+0.1%
YTD
+43.8%
1Y
+155.0%
From 52W high
−4.6%
From 52W low
+165.6%
$57
$158
52-week range, adjusted closes · the dot is the last close
Ticker Nerd rank

PVLA stock analysis: one number for the whole business

Consensus tells you what everyone already believes. The model scores Palvella Therapeutics, Inc. on its factor families — the same systematic rank behind the Ticker Nerd portfolio.

Where the model ranks itAs at 18 Sept 2026
32 / 100

Percentile across ~4,600 US stocks on Ticker Nerd’s systematic factor model. Higher is better. How the model is built and tested

Momentum
96
Value
78
Volatility
72
Quality
51
Accruals
45
Size
34
Revisions
28
Issuance
11
Growth
8

Momentum (96): The shares have been drifting up relative to others.

Growth (8): Sales and profits are flat, shrinking, or growing more slowly than they were.

Built and run by Aslam Ghouse, an ex-Goldman Sachs quant trader with fourteen years in markets.

Wall Street

PVLA stock forecast 2026-2027: analyst price targets & predictions

The bullish and bearish analyst opinions on PVLA, reported as data — targets and ratings, the market's view beside the model's.

Share price and the analyst range, 12 monthsAdjusted close, US dollars
$50$100$150$200$250$300Oct 25Jan 26Apr 26Jul 26PVLAHigh $270Median $232Low $205

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Data provided by Twelve Data

What Wall Street says15 analysts
15 Buy0 Hold0 Sell
Low $205Median $232High $270

The green dot is the last close — the median target sits +54.1% from it.

Recent analyst actionsNewest first
DateFirmActionRatingTarget
21 May 2026Chardan CapitalMaintainsBuy$240
21 May 2026Stephens & Co.ReiteratesOverweight$220
12 May 2026Stephens & Co.InitiatesOverweight
31 Mar 2026Chardan CapitalMaintainsBuy
24 Mar 2026HC Wainwright & Co.MaintainsBuy
16 Mar 2026Chardan CapitalMaintainsBuy
25 Feb 2026BTIGMaintainsBuy
25 Feb 2026MizuhoMaintainsOutperform
24 Feb 2026Chardan CapitalMaintainsBuy
24 Feb 2026HC Wainwright & Co.MaintainsBuy
29 Jan 2026BTIGReiteratesBuy
16 Jan 2026BTIGReiteratesBuy
7 Jan 2026MizuhoInitiatesOutperform
16 Dec 2025Canaccord GenuityMaintainsBuy
16 Dec 2025Chardan CapitalMaintainsBuy
16 Dec 2025TD CowenMaintainsBuy
16 Dec 2025Truist SecuritiesMaintainsBuy
15 Dec 2025BTIGMaintainsBuy
15 Dec 2025HC Wainwright & Co.MaintainsBuy
5 Dec 2025BTIGInitiatesBuy

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Market Radar

This page is one stock. Monday covers all of them.

Computed off the Friday close and sent before the US open.

Market Radar reports the week’s largest rank changes across roughly 4,600 US stocks, the factor behind each one, and where the market went. PVLA appears on the weeks it earns a place.

Free, every Monday. Unsubscribe any time.

Performance

PVLA vs the S&P 500

Both lines are total return — dividends reinvested — so the comparison is honest on both sides.

Over the twelve months to 18 Sept 2026, Palvella Therapeutics, Inc. returned +155.0% against +16.3% for the S&P 500, dividends included.

PVLA vs S&P 500, last 12 monthsTotal return, rebased to 100
100150200250Oct 25Jan 26Apr 26Jul 26PVLAS&P 500

Download this chart as an image — free to reuse; link this page as the source.

Data provided by Twelve Data

Estimates

PVLA analyst estimate revisions

Not the forecast itself — the direction analysts are revising it. Revision direction is one of the model's factor families.

Which way the estimates are movingNext fiscal year
Analysts raising
1
Analysts cutting
7
Fundamentals

Palvella Therapeutics, Inc. (PVLA) financial data

A margin means little on its own. Each bar marks where the figure sits across the whole US universe we score.

Valuation
Trailing P/E
13.7×

Cheaper than 49% of US stocks

Price / sales
Price / book
10.0×

Cheaper than 9% of US stocks

EV / EBITDA
−55.0×

Cheaper than 95% of US stocks

Growth & margins
Revenue growth (YoY)
Earnings growth (YoY)
Gross margin
Operating margin
0.0%

Higher than 32% of US stocks

Net margin
0.0%

Higher than 30% of US stocks

Returns & dividend
Return on equity
−46.6%

Higher than 22% of US stocks

Return on assets
−22.1%

Higher than 18% of US stocks

Dividend yield

Bars mark the percentile across the ~4,600 US stocks Ticker Nerd covers, among those reporting the figure.

Key statistics

Palvella Therapeutics, Inc. (PVLA) statistics: revenue, profit & scale

The headline figures, each with its date. Every row carries its own link — cite it straight from here.

  • Palvella Therapeutics, Inc. has a market value of $2.2B and an enterprise value of $1.9B.

  • Revenue in the twelve months to 30 June 2026: $0.0.

  • Net income over the same four quarters: −$61.7M.

  • Free cash flow in the twelve months to 30 June 2026: −$36.5M.

  • Shares outstanding: 14.4M.

  • Trailing P/E: 13.7×; forward P/E: −20.1× — the forward figure prices analyst consensus estimates, not reported earnings.

  • Palvella Therapeutics, Inc. employs 29 people.

Statement figures: company filings via Twelve Data, four quarters to 30 June 2026 · market figures as at 19 Sept 2026

Data provided by Twelve Data

Peers

PVLA vs competitors

The nearest names by industry and size, scored by the same model — like for like.

Its peer group, ranked by the same modelBiotechnology
CompanyMarket capTKN rank
PVLAPalvella Therapeutics, Inc.$2.2B
32
GENBGenerate Biomedicines, Inc.$2.2B
1
TRVITrevi Therapeutics, Inc.$2.1B
53
OCULOcular Therapeutix, Inc.$2.1B
35
SRPTSarepta Therapeutics, Inc.$2.1B
71
URGNUroGen Pharma Ltd.$2.1B
82
NKTRNektar Therapeutics$2.2B
51

Look up any of the roughly 4,600 stocks we score.

The rank is the raw material. Whether the rules would actually own Palvella Therapeutics, Inc. — and when they’d sell — is the membership. See the Ticker Nerd 20 →

News

Latest PVLA news & analysis

Palvella Therapeutics Appoints James R. Treat, M.D.

GlobeNewsWire · 9 Sept 2026positive

Palvella Therapeutics announced the appointment of James R. Treat, M.D., who brings expertise in cutaneous vascular anomalies, including microcystic lymphatic malformations, venous malformations, and angiokeratomas.

Why it matters — A PVLA watcher would care because this appointment adds specialized dermatologic expertise relevant to the company's therapeutic focus areas.

Palvella Therapeutics to Participate in Upcoming Healthcare Investor Conferences

GlobeNewsWire · 2 Sept 2026neutral

Palvella Therapeutics announced that CEO Wes Kaupinen will participate in two upcoming healthcare investor conferences. The company is a clinical-stage biopharmaceutical firm focused on developing therapies for rare skin diseases and vascular malformations.

Why it matters — A PVLA watcher would care because the CEO's participation in investor conferences provides opportunities for the company to present its pipeline and strategies to the investment community.

Palvella Therapeutics Completes Rolling Submission of New Drug Application to FDA for QTORIN™ Rapamycin for the Treatment of Microcystic Lymphatic Malformations

GlobeNewsWire · 31 Aug 2026positive

Palvella Therapeutics completed the rolling submission of its New Drug Application to the FDA for QTORIN rapamycin, intended for the treatment of microcystic lymphatic malformations. The therapy has the potential to become the first FDA-approved treatment for this condition, which affects an estimated more than 30,000 pediatric and adult patients in the U.S.

Why it matters — This milestone moves Palvella closer to potentially securing the first FDA-approved therapy for microcystic lymphatic malformations, a significant commercial opportunity for the company.

Palvella Therapeutics: First Approval Could Unlock A Rare-Disease Commercial Flywheel

Seeking Alpha · 19 Aug 2026positive

Palvella Therapeutics is advancing QTORIN rapamycin for microcystic lymphatic malformations, having posted positive Phase 3 SELVA data and begun a rolling NDA submission. The company plans to expand QTORIN across multiple mTOR-driven dermatological indications, supported by a recent $230M equity raise.

Why it matters — PVLA watchers would care because the first approval and a recent $230M equity raise could help Palvella build a repeatable multi-indication commercial platform while mitigating typical small-biotech funding risks.

Palvella Therapeutics Eyes 2027 QTORIN Approval as Rare-Disease Pipeline Expands

MarketBeat · 16 Aug 2026positive

Palvella Therapeutics is advancing topical therapies for rare skin diseases and vascular malformations lacking FDA-approved treatments, with its lead candidate, QTORIN rapamycin, moving toward a planned New Drug Application submission for microcystic lymphatic malformations. The item notes a 2027 approval target as the rare-disease pipeline expands.

Why it matters — A PVLA watcher would care because the planned NDA submission for QTORIN rapamycin brings the company's lead candidate closer to a milestone in an area with no FDA-approved treatments.

FAQ

Frequently asked questions about PVLA stock

What is the PVLA stock price forecast for 2026-2027?

The 15 Wall Street analysts covering Palvella Therapeutics, Inc. have a median 12-month price target of $232, with estimates ranging from $205 to $270. These are third-party analyst estimates, not Ticker Nerd forecasts, and they are frequently wrong.

Is PVLA stock a buy right now?

Of the 15 analysts covering Palvella Therapeutics, Inc., 15 rate it a Buy, 0 a Hold and 0 a Sell. Ticker Nerd's systematic factor model ranks Palvella Therapeutics, Inc. 32 out of 100 across roughly 4,600 US stocks as at 18 Sept 2026. None of this is personal advice — it does not consider your circumstances.

How does Ticker Nerd's model rank PVLA?

As at 18 Sept 2026, Palvella Therapeutics, Inc. ranks 32 out of 100 on Ticker Nerd's systematic factor model — a percentile across roughly 4,600 US stocks, built from its factor families. Its strongest factor family is Momentum (96 of 100).

Will PVLA stock go up?

No one can know that. What the data says: the median 12-month target from 15 analysts implies +54.1% from the last close, and Ticker Nerd's factor model ranks Palvella Therapeutics, Inc. 32 out of 100 as at 18 Sept 2026. Analyst targets are third-party estimates and frequently wrong; none of this is personal advice.

What is the PVLA stock forecast for 2030?

No analyst covering Palvella Therapeutics, Inc. publishes a 2030 price target — Wall Street targets run 12 to 18 months out. Sites quoting a 2030 price for PVLA are extrapolating price history, which says nothing about the business. The furthest attributed numbers are the current analyst targets: $205 to $270 over the next 12 months.

How has PVLA stock performed over the past year?

Palvella Therapeutics, Inc. returned +155.0% over the 12 months to 18 Sept 2026, with dividends reinvested. Past performance does not indicate future returns.

What does Palvella Therapeutics, Inc. do?

Palvella Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing and commercializing therapies for serious, rare skin diseases and vascular malformations with no FDA-approved treatment options.

What is the latest news on PVLA?

The most recent item we track (GlobeNewsWire, 9 Sept 2026): "Palvella Therapeutics Appoints James R. Treat, M.D.". Palvella Therapeutics announced the appointment of James R. Treat, M.D., who brings expertise in cutaneous vascular anomalies, including microcystic lymphatic malformations, venous malformations, and angiokeratomas.

Company

About Palvella Therapeutics, Inc.

Palvella Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing and commercializing therapies for serious, rare skin diseases and vascular malformations with no FDA-approved treatment options. The company centers its work on dermatology-focused rare disease programs, using its proprietary QTORIN platform to create topical therapies designed for localized delivery in difficult-to-treat conditions. Its current pipeline includes product candidates being studied for microcystic lymphatic malformations, cutaneous venous malformations, and clinically significant angiokeratomas, reflecting a focus on genetically driven and orphan skin disorders. Palvella Therapeutics serves the rare disease and specialty dermatology markets, where targeted medicines can address conditions that are often chronic, burdensome, and underserved by existing therapies. Palvella Therapeutics, Inc. is headquartered in Wayne, Pennsylvania.

CEO Mr. Wesley H. Kaupinen · 29 employees · United States · https://palvellatx.com