Xencor: 'Strong Buy' On Positive XmAb819 ESMO Data ccRCC And Potential For FDA Accelerated Approval Pathway
The Seeking Alpha item reports positive phase 1 dose-expansion results for Xencor’s XmAb819 in advanced ccRCC, including a 45.5% cORR at 400 mcg/kg. It says the company plans pivotal phase 3 development and expects to discuss a potential FDA Accelerated Approval pathway in 1H 2027.
Why it matters — The results and stated development plans provide updates on XmAb819’s progress, alongside Xencor’s expansion of the program into other ENPP3+ solid tumors and continued XmAb942 development.