ZYMEZYMEHealthcare · Biotechnology

ZYME Stock Forecast: Zymeworks, Inc. Price Predictions for 2026-2027

Last close, 14 Aug 2026
$25
−2.48% on the day

The 13 Wall Street analysts covering Zymeworks, Inc. hold a median 12-month price target of $39 — +53.3% from the last close. Ticker Nerd's systematic factor model, run across ~4,600 US stocks, ranks it 70 of 100 as at 15 Aug 2026 — in the upper half. Here, the model and the Street point the same way.

Market cap
$1.8B
Ticker Nerd rank
70 / 100
Median analyst target
$39
Analysts covering
13
Total return, dividends reinvested
1W
+6.7%
1M
+1.9%
YTD
−4.6%
1Y
+75.7%
From 52W high
−12.0%
From 52W low
+79.3%
$14
$29
52-week range, adjusted closes · the dot is the last close
Ticker Nerd rank

ZYME stock analysis: one number for the whole business

Consensus tells you what everyone already believes. The model scores Zymeworks, Inc. on its factor families — the same systematic rank behind the Ticker Nerd portfolio.

Where the model ranks itAs at 15 Aug 2026
70 / 100

Percentile across ~4,600 US stocks on Ticker Nerd’s systematic factor model. Higher is better. How the model is built and tested

Volatility
95
Value
94
Momentum
87
Quality
70
Accruals
69
Revisions
50
Size
38
Issuance
31
Growth
24

Volatility (95): The share price has been relatively steady.

Growth (24): Sales and profits are flat, shrinking, or growing more slowly than they were.

Built and run by Aslam Ghouse, an ex-Goldman Sachs quant trader with fourteen years in markets.

Wall Street

ZYME stock forecast 2026-2027: analyst price targets & predictions

The bullish and bearish analyst opinions on ZYME, reported as data — targets and ratings, the market's view beside the model's.

Share price and the analyst range, 12 monthsAdjusted close, US dollars
$10$20$30$40$50$60Oct 25Jan 26Apr 26Jul 26ZYMEHigh $58Median $39Low $31

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

What Wall Street says13 analysts
13 Buy0 Hold0 Sell
Low $31Median $39High $58

The green dot is the last close — the median target sits +53.3% from it.

Recent analyst actionsNewest first

Of the 20 most recent actions, 6 moved their price target up and 0 moved it down.

DateFirmActionRatingTarget
10 Aug 2026B. Riley SecuritiesReiteratesBuy$40$44
7 Aug 2026Truist SecuritiesMaintainsBuy$31$32
7 Aug 2026Wells FargoMaintainsOverweight$37$40
5 Aug 2026HC Wainwright & Co.MaintainsBuy$46$51
7 July 2026Truist SecuritiesMaintainsBuy
7 July 2026Truist SecuritiesMaintainsBuy$28$31
30 June 2026Wells FargoMaintainsOverweight
30 June 2026Wells FargoMaintainsOverweight$34$37
3 June 2026HC Wainwright & Co.ReiteratesBuy
8 May 2026Wells FargoMaintainsOverweight
9 Mar 2026Evercore ISI GroupMaintainsOutperform
6 Mar 2026HC Wainwright & Co.MaintainsBuy
3 Mar 2026Leerink PartnersMaintainsOutperform
3 Mar 2026StifelMaintainsBuy
17 Dec 2025Truist SecuritiesInitiatesBuy
12 Dec 2025Wells FargoUpgradeOverweight
3 Dec 2025CitizensInitiatesMarket Outperform
21 Nov 2025B. Riley SecuritiesReiteratesBuy
19 Nov 2025StifelMaintainsBuy
19 Nov 2025Wells FargoMaintainsEqual-Weight

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Market Radar

This page is one stock. Monday covers all of them.

Computed off the Friday close and sent before the US open.

Market Radar reports the week’s largest rank changes across roughly 4,600 US stocks, the factor behind each one, and where the market went. ZYME appears on the weeks it earns a place.

Free, every Monday. Unsubscribe any time.

Estimates

ZYME analyst estimate revisions

Not the forecast itself — the direction analysts are revising it. Revision direction is one of the model's factor families.

Which way the estimates are movingNext fiscal year
EPS revision, 90 days
−2.4%
Analysts raising
0
Analysts cutting
0
Fundamentals

Zymeworks, Inc. (ZYME) financial data

A margin means little on its own. Each bar marks where the figure sits across the whole US universe we score.

Valuation
Trailing P/E
3.8×

Cheaper than 68% of US stocks

Price / sales
47.6×

Cheaper than 6% of US stocks

Price / book
11.4×

Cheaper than 9% of US stocks

EV / EBITDA
−9.8×

Cheaper than 84% of US stocks

Growth & margins
Revenue growth (YoY)
−90.6%

Higher than 2% of US stocks

Earnings growth (YoY)
−90.6%

Higher than 3% of US stocks

Gross margin
Operating margin
−919.0%

Higher than 6% of US stocks

Net margin
0.0%

Higher than 30% of US stocks

Returns & dividend
Return on equity
−72.3%

Higher than 17% of US stocks

Return on assets
−24.1%

Higher than 17% of US stocks

Dividend yield

Bars mark the percentile across the ~4,600 US stocks Ticker Nerd covers, among those reporting the figure.

Peers

ZYME vs competitors

The nearest names by industry and size, scored by the same model — like for like.

Its peer group, ranked by the same modelBiotechnology
CompanyMarket capTKN rank
ZYMEZymeworks, Inc.$1.8B
70
AVLNAvalyn Pharma, Inc.$1.7B
1
ZBIOZenas BioPharma, Inc.$1.9B
23
ANABAnaptysBio, Inc.$1.7B
100
DMRADamora Therapeutics, Inc.$1.9B
45
SNDXSyndax Pharmaceuticals, Inc.$1.7B
66
KARDKardigan, Inc.$1.9B
0

Look up any of the roughly 4,600 stocks we score.

The rank is the raw material. Whether the rules would actually own Zymeworks, Inc. — and when they’d sell — is the membership. See the Ticker Nerd 20 →

News

Latest ZYME news & analysis

TBPH Meets Q2 Earnings Estimates, to be Acquired by Zymeworks

Zacks Investment Research · 11 Aug 2026positive

Theravance Biopharma reported second-quarter earnings that matched estimates. Following the discontinuation of ampreloxetine, the company implemented cost cuts and is set to be acquired by Zymeworks in a $929 million deal.

Why it matters — A Zymeworks watcher would care because this acquisition expands Zymeworks' scope and represents a significant corporate development for the company.

Zymeworks Inc. (ZYME) Reports Q2 Loss, Beats Revenue Estimates

Zacks Investment Research · 7 Aug 2026negative

Zymeworks reported a Q2 loss of $0.62 per share, wider than the Zacks Consensus Estimate of a $0.56 loss and versus earnings of $0.03 per share in the same quarter a year ago, while revenue beat estimates.

Why it matters — The results show a year-over-year swing from profit to a loss that was larger than analysts expected, which is directly relevant to ZYME watchers tracking quarterly performance.

Zymeworks Provides Corporate Update and Reports Second Quarter 2026 Financial Results

GlobeNewsWire · 6 Aug 2026positive

Zymeworks reported its second quarter 2026 financial results and corporate update, highlighting a U.S. PDUFA target action date for zanidatamab that could trigger a $250 million U.S. approval milestone and up to $190 million in additional global regulatory milestones. The company also expects its acquisition of Theravance Biopharma to close in the second half of 2026, advanced its R&D pipeline, repurchased $49.4 million of common shares, and held $322.5 million in cash and securities as of June 30, 2026.

Why it matters — The update signals key near-term catalysts—zanidatamab's U.S. approval milestone and the Theravance acquisition adding commercial cash flows—alongside a strong cash position and an active share repurchase program.

FAQ

Frequently asked questions about ZYME stock

What is the ZYME stock price forecast for 2026-2027?

The 13 Wall Street analysts covering Zymeworks, Inc. have a median 12-month price target of $39, with estimates ranging from $31 to $58. These are third-party analyst estimates, not Ticker Nerd forecasts, and they are frequently wrong.

Is ZYME stock a buy right now?

Of the 13 analysts covering Zymeworks, Inc., 13 rate it a Buy, 0 a Hold and 0 a Sell. Ticker Nerd's systematic factor model ranks Zymeworks, Inc. 70 out of 100 across roughly 4,600 US stocks as at 15 Aug 2026. None of this is personal advice — it does not consider your circumstances.

How does Ticker Nerd's model rank ZYME?

As at 15 Aug 2026, Zymeworks, Inc. ranks 70 out of 100 on Ticker Nerd's systematic factor model — a percentile across roughly 4,600 US stocks, built from its factor families. Its strongest factor family is Volatility (95 of 100).

Will ZYME stock go up?

No one can know that. What the data says: the median 12-month target from 13 analysts implies +53.3% from the last close, and Ticker Nerd's factor model ranks Zymeworks, Inc. 70 out of 100 as at 15 Aug 2026. Analyst targets are third-party estimates and frequently wrong; none of this is personal advice.

What is the ZYME stock forecast for 2030?

No analyst covering Zymeworks, Inc. publishes a 2030 price target — Wall Street targets run 12 to 18 months out. Sites quoting a 2030 price for ZYME are extrapolating price history, which says nothing about the business. The furthest attributed numbers are the current analyst targets: $31 to $58 over the next 12 months.

How has ZYME stock performed over the past year?

Zymeworks, Inc. returned +75.7% over the 12 months to 14 Aug 2026, with dividends reinvested. Past performance does not indicate future returns.

What does Zymeworks, Inc. do?

Zymeworks Inc. is a biotechnology company that focuses on innovating biotherapeutics for the treatment of cancer and autoimmune diseases.

What is the latest news on ZYME?

The most recent item we track (Zacks Investment Research, 11 Aug 2026): "TBPH Meets Q2 Earnings Estimates, to be Acquired by Zymeworks". Theravance Biopharma reported second-quarter earnings that matched estimates. Following the discontinuation of ampreloxetine, the company implemented cost cuts and is set to be acquired by Zymeworks in a $929 million deal.

Company

About Zymeworks, Inc.

Zymeworks Inc. is a biotechnology company that focuses on innovating biotherapeutics for the treatment of cancer and autoimmune diseases. The company's core mission revolves around developing novel, multifunctional therapeutics with the potential to improve efficacy and reduce side effects compared to conventional cancer treatments. Zymeworks utilizes its proprietary platforms, such as the Azymetric and EFECT technologies, which enable the creation of multifunctional antibody therapeutics. These assets are significant in sectors such as oncology and immunology, addressing unmet needs with therapies aimed at complex and difficult-to-treat conditions. Based in Canada, Zymeworks collaborates with leading global pharmaceutical companies to enhance the reach and impact of its research. In the financial market, Zymeworks Inc. is notable for its strategic partnerships and potential for contributing to advancements in precision medicine, emphasizing its role not only in scientific innovation but also as a key player in the biotech industry's approach to personalized healthcare solutions.

CEO Mr. Kenneth H. Galbraith C.A. · 231 employees · United States · https://www.zymeworks.com