ZYMEZYMEHealthcare · Biotechnology

ZYME Stock Forecast: Zymeworks, Inc. Price Predictions for 2026-2027

Last close, 30 Oct 2026
$29
−0.38% on the day

The 14 Wall Street analysts covering Zymeworks, Inc. hold a median 12-month price target of $38 — +32.9% from the last close. Ticker Nerd's systematic factor model, run across ~4,600 US stocks, ranks it 63 of 100 as at 31 Oct 2026 — in the upper half.

Market cap
$2.1B
Ticker Nerd rank
63/ 100
Median analyst target
$38
Analysts covering
14
Revenue$4.6M−90.6% y/y
Operating income−$42.1M
Net income−$45.0M
Free cash flow−$31.9M
Quarterly, 8 quarters to 30 June 2026 · latest quarter's figure shown
Total return, dividends reinvested
1W
+1.3%
1M
+8.0%
YTD
+8.6%
1Y
+49.6%
From 52W high
−7.9%
From 52W low
+73.8%
$16
$31
52-week range, adjusted closes · the dot is the last close
Ticker Nerd rank

ZYME stock analysis: one number for the whole business

Consensus tells you what everyone already believes. The model scores Zymeworks, Inc. on its factor families — the same systematic rank behind the Ticker Nerd portfolio.

Where the model ranks itAs at 31 Oct 2026
63/ 100

Percentile across ~4,600 US stocks on Ticker Nerd’s systematic factor model. Higher is better. How the model is built and tested

Volatility
91
Value
90
Momentum
86
Accruals
69
Quality
59
Revisions
48
Size
35
Issuance
31
Growth
26

Volatility (91): The share price has been relatively steady.

Growth (26): Sales and profits are flat, shrinking, or growing more slowly than they were.

Built and run by Aslam Ghouse, an ex-Goldman Sachs systematic trader with 15+ years in markets.

Wall Street

ZYME stock forecast 2026-2027: analyst price targets & predictions

The bullish and bearish analyst opinions on ZYME, reported as data — targets and ratings, the market's view beside the model's.

Share price and the analyst range, 12 monthsAdjusted close, US dollars
$20$30$40$50$60Jan 26Apr 26Jul 26Oct 26ZYMEHigh $60Median $38Low $32

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Data provided by Twelve Data

What Wall Street says14 analysts
14 Buy0 Hold0 Sell
Low $32Median $38High $60

The green dot is the last close — the median target sits +32.9% from it.

Recent analyst actionsNewest first

Of the 20 most recent actions, 8 moved their price target up and 0 moved it down.

DateFirmActionRatingTarget
7 Oct 2026Truist SecuritiesMaintainsBuy$32 → $34
29 Sept 2026CitigroupMaintainsBuy$38 → $39
29 Sept 2026CitigroupMaintainsBuy—
17 Sept 2026Wolfe ResearchInitiatesOutperform—
17 Sept 2026Wolfe ResearchInitiatesOutperform—
3 Sept 2026JP MorganMaintainsOverweight$31 → $33
3 Sept 2026JP MorganMaintainsOverweight—
26 Aug 2026CitigroupMaintainsBuy—
26 Aug 2026CitigroupMaintainsBuy$37 → $38
26 Aug 2026CitizensReiteratesMarket Outperform$32
26 Aug 2026CitizensReiteratesMarket Outperform—
26 Aug 2026HC Wainwright & Co.MaintainsBuy$51 → $55
26 Aug 2026HC Wainwright & Co.MaintainsBuy—
10 Aug 2026B. Riley SecuritiesReiteratesBuy$40 → $44
10 Aug 2026B. Riley SecuritiesReiteratesBuy—
7 Aug 2026Truist SecuritiesMaintainsBuy—
7 Aug 2026Truist SecuritiesMaintainsBuy$31 → $32
7 Aug 2026Wells FargoMaintainsOverweight$37 → $40
7 Aug 2026Wells FargoMaintainsOverweight—
5 Aug 2026HC Wainwright & Co.MaintainsBuy—

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Market Radar

This page is one stock. Monday covers all of them.

ZYME appears in the Radar on the weeks it earns a place.

  • Market Radar, every Monday: the week's biggest rank moves across ~4,600 US stocks, and the reason for each.
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Performance

ZYME vs the S&P 500

Both lines are total return — dividends reinvested — so the comparison is honest on both sides.

Over the twelve months to 30 Oct 2026, Zymeworks, Inc. returned +49.6% against +12.4% for the S&P 500, dividends included.

ZYME vs S&P 500, last 12 monthsTotal return, rebased to 100
80100120140160Jan 26Apr 26Jul 26Oct 26ZYMES&P 500

Download this chart as an image — free to reuse; link this page as the source.

Data provided by Twelve Data

Estimates

ZYME analyst estimate revisions

Not the forecast itself — the direction analysts are revising it. Revision direction is one of the model's factor families.

Which way the estimates are movingThis fiscal year
EPS revision, 90 days
−10.0%
Analysts raising
1
Analysts cutting
2
Fundamentals

Zymeworks, Inc. (ZYME) financial data

A margin means little on its own. Each bar marks where the figure sits across the whole US universe we score.

Valuation
Trailing P/E
3.8×

Cheaper than 67% of US stocks

Price / sales
55.6×

Cheaper than 5% of US stocks

Price / book
25.5×

Cheaper than 4% of US stocks

EV / EBITDA
−11.8×

Cheaper than 86% of US stocks

Growth & margins
Revenue growth (YoY)
−90.6%

Higher than 2% of US stocks

Earnings growth (YoY)
−90.6%

Higher than 3% of US stocks

Gross margin
—
Operating margin
−919.0%

Higher than 5% of US stocks

Net margin
0.0%

Higher than 30% of US stocks

Returns & dividend
Return on equity
−72.3%

Higher than 17% of US stocks

Return on assets
−24.1%

Higher than 17% of US stocks

Dividend yield
0.0%

Higher than 1% of US dividend payers

Bars mark the percentile across the ~4,600 US stocks Ticker Nerd covers, among those reporting the figure.

Key statistics

Zymeworks, Inc. (ZYME) statistics: revenue, profit & scale

The headline figures, each with its date. Every row carries its own link — cite it straight from here.

  • Zymeworks, Inc. has a market value of $2.1B and an enterprise value of $1.8B.

  • Revenue in the twelve months to 30 June 2026: $37.1M. The latest quarter shrank 90.6% year on year.

  • Net income over the same four quarters: −$150.0M, a −404.0% net margin.

  • Diluted earnings per share, trailing twelve months: $−2.02.

  • Free cash flow in the twelve months to 30 June 2026: −$120.7M.

  • Zymeworks, Inc. spent $169.8M on share buybacks in the twelve months to 30 June 2026.

  • Shares outstanding: 72.0M.

  • Trailing P/E: 3.8×; forward P/E: 23.6× — the forward figure prices analyst consensus estimates, not reported earnings.

  • Forward dividend yield: 0.00%, paying out 0% of earnings.

  • Zymeworks, Inc. employs 231 people — $161K of revenue per employee.

Statement figures: company filings via Twelve Data, four quarters to 30 June 2026 · market figures as at 30 Oct 2026

Data provided by Twelve Data

Peers

ZYME vs competitors

The nearest names by industry and size, scored by the same model — like for like.

Its peer group, ranked by the same modelBiotechnology
CompanyMarket capTKN rank
ZYMEZymeworks, Inc.$2.1B63
VCELVericel Corp.$2.0B94
FTREFortrea Holdings, Inc.$2.0B93
PVLAPalvella Therapeutics, Inc.$2.1B35
MRVIMaravai Lifesciences Holdings, Inc.$2.0B85
SEPNSepterna, Inc.$2.0B88
SLSSELLAS Life Sciences Group, Inc.$2.0B63

Look up any of the roughly 4,600 stocks we score.

The rank is the raw material. Whether the rules would actually own Zymeworks, Inc. — and when they’d sell — is the membership. See the Ticker Nerd 20 →

News

Latest ZYME news & analysis

Zymeworks Inc. (ZYME) to Report Q3 Results: Wall Street Expects Earnings Growth

Zacks Investment Research · 29 Oct 2026negative

Zacks says Zymeworks lacks the combination of two key ingredients associated with a likely earnings beat ahead of its upcoming Q3 report. The item says the report’s key expectations are being outlined.

Why it matters — ZYME watchers may note the article’s caution about the likelihood of an earnings beat before the company reports Q3 results.

Zymeworks Highlights ZW191 Ovarian Cancer Responses, Roche Deal Upside

MarketBeat · 27 Oct 2026positive

Zymeworks outlined a partnering-focused research strategy, presented updated ZW191 clinical data in platinum-resistant ovarian cancer, and discussed its recently announced Roche collaboration involving DLL3-targeting T-cell engager ZW209.

Why it matters — The update covers Zymeworks’ clinical progress with ZW191 and a collaboration that forms part of its partnering strategy.

FAQ

Frequently asked questions about ZYME stock

What is the ZYME stock price forecast for 2026-2027?

The 14 Wall Street analysts covering Zymeworks, Inc. have a median 12-month price target of $38, with estimates ranging from $32 to $60. These are third-party analyst estimates, not Ticker Nerd forecasts, and they are frequently wrong.

Is ZYME stock a buy right now?

Of the 14 analysts covering Zymeworks, Inc., 14 rate it a Buy, 0 a Hold and 0 a Sell. Ticker Nerd's systematic factor model ranks Zymeworks, Inc. 63 out of 100 across roughly 4,600 US stocks as at 31 Oct 2026. None of this is personal advice — it does not consider your circumstances.

How does Ticker Nerd's model rank ZYME?

As at 31 Oct 2026, Zymeworks, Inc. ranks 63 out of 100 on Ticker Nerd's systematic factor model — a percentile across roughly 4,600 US stocks, built from its factor families. Its strongest factor family is Volatility (91 of 100).

Will ZYME stock go up?

No one can know that. What the data says: the median 12-month target from 14 analysts implies +32.9% from the last close, and Ticker Nerd's factor model ranks Zymeworks, Inc. 63 out of 100 as at 31 Oct 2026. Analyst targets are third-party estimates and frequently wrong; none of this is personal advice.

What is the ZYME stock forecast for 2030?

No analyst covering Zymeworks, Inc. publishes a 2030 price target — Wall Street targets run 12 to 18 months out. Sites quoting a 2030 price for ZYME are extrapolating price history, which says nothing about the business. The furthest attributed numbers are the current analyst targets: $32 to $60 over the next 12 months.

How has ZYME stock performed over the past year?

Zymeworks, Inc. returned +49.6% over the 12 months to 30 Oct 2026, with dividends reinvested. Past performance does not indicate future returns.

What does Zymeworks, Inc. do?

Zymeworks Inc. is a biotechnology company focused on discovering, developing, and commercializing multifunctional biotherapeutics for cancer and other serious diseases.

What is the latest news on ZYME?

The most recent item we track (Zacks Investment Research, 29 Oct 2026): "Zymeworks Inc. (ZYME) to Report Q3 Results: Wall Street Expects Earnings Growth". Zacks says Zymeworks lacks the combination of two key ingredients associated with a likely earnings beat ahead of its upcoming Q3 report. The item says the report’s key expectations are being outlined.

Company

About Zymeworks, Inc.

Zymeworks Inc. is a biotechnology company focused on discovering, developing, and commercializing multifunctional biotherapeutics for cancer and other serious diseases. The company operates across therapeutic areas including oncology, inflammation, and autoimmune disease, using proprietary antibody-based platforms to design differentiated drug candidates. Its current portfolio includes clinical-stage programs and licensed healthcare assets, supported by integrated research, development, and commercialization capabilities. Zymeworks also works with antibody-drug conjugate technologies and other advanced biologic platforms aimed at improving precision and therapeutic performance across difficult-to-treat conditions. With operations centered on modern drug innovation, Zymeworks Inc. plays a role in advancing next-generation treatments within the global biopharmaceutical market.

CEO Mr. Kenneth H. Galbraith C.A. · 231 employees · United States · https://www.zymeworks.com