OPKOPKHealthcare · Diagnostics & Research

OPK Stock Forecast: OPKO Health, Inc. Price Predictions for 2026-2027

Last close, 3 Aug 2026
$1.31
−0.76% on the day

The 6 Wall Street analysts covering OPKO Health, Inc. hold a median 12-month price target of $3 — +129.0% from the last close. Ticker Nerd's systematic factor model, run across ~4,600 US stocks, ranks it 79 of 100 as at 1 Aug 2026 — inside the top quartile. Here, the model and the Street point the same way.

Market cap
$985.2M
Ticker Nerd rank
79 / 100
Median analyst target
$3.00
Analysts covering
6
Total return, dividends reinvested
1W
+5.6%
1M
−13.8%
YTD
+4.0%
1Y
+10.1%
From 52W high
−20.6%
From 52W low
+19.1%
$1.10
$1.65
52-week range, adjusted closes · the dot is the last close
Ticker Nerd rank

OPK stock analysis: one number for the whole business

Consensus tells you what everyone already believes. The model scores OPKO Health, Inc. on its factor families — the same systematic rank behind the Ticker Nerd portfolio.

Where the model ranks itAs at 1 Aug 2026
79 / 100

Percentile across ~4,600 US stocks on Ticker Nerd’s systematic factor model. Higher is better. How the model is built and tested

Growth
91
Revisions
88
Issuance
78
Momentum
59
Accruals
56
Volatility
50
Quality
45
Size
45
Value
33

Growth (91): Sales and profits are climbing, and climbing faster than before.

Value (33): The shares cost a lot relative to the profits and assets behind them.

The rank is the raw material. Whether the rules would actually own OPKO Health, Inc. — and when they’d sell — is the membership.

Wall Street

OPK stock forecast 2026-2027: analyst price targets & predictions

The bullish and bearish analyst opinions on OPK, reported as data — targets and ratings, the market's view beside the model's.

Share price and the analyst range, 12 monthsAdjusted close, US dollars
$0.00$2.00$4.00$6.00$8.00Oct 25Jan 26Apr 26Jul 26OPKHigh $8.50Median $3.00Low $3.00

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

What Wall Street says6 analysts
4 Buy2 Hold0 Sell
Low $3.00Median $3.00High $8.50

The green dot is the last close — the median target sits +129.0% from it.

Recent analyst actionsNewest first
DateFirmActionRatingTarget
29 Apr 2026Barrington ResearchDowngradeMarket Perform
2 Mar 2026Barrington ResearchMaintainsOutperform
20 Nov 2025JP MorganInitiatesNeutral
31 Oct 2025JefferiesDowngradeHold
30 Oct 2025Barrington ResearchMaintainsOutperform
1 May 2025Barrington ResearchMaintainsOutperform
25 Apr 2025JP MorganInitiatesNeutral
7 Apr 2025HC Wainwright & Co.ReiteratesBuy
19 Mar 2025HC Wainwright & Co.ReiteratesBuy
12 Mar 2025Barrington ResearchMaintainsOutperform
12 Mar 2025HC Wainwright & Co.ReiteratesBuy
3 Mar 2025HC Wainwright & Co.ReiteratesBuy
28 Feb 2025Barrington ResearchMaintainsOutperform
8 Jan 2025HC Wainwright & Co.MaintainsBuy
8 Nov 2024Barrington ResearchMaintainsOutperform
26 Sept 2024HC Wainwright & Co.ReiteratesBuy
20 Sept 2024Barrington ResearchMaintainsOutperform
17 Sept 2024HC Wainwright & Co.ReiteratesBuy
17 Sept 2024Piper SandlerReiteratesOverweight
8 Aug 2024Barrington ResearchMaintainsOutperform

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Estimates

OPK analyst estimate revisions

Not the forecast itself — the direction analysts are revising it. Revision direction is one of the model's factor families.

Which way the estimates are movingNext fiscal year
Analysts raising
0
Analysts cutting
1
Fundamentals

OPKO Health, Inc. (OPK) financial data

A margin means little on its own. Each bar marks where the figure sits across the whole US universe we score.

Valuation
Trailing P/E
−4.4×

Cheaper than 89% of US stocks

Price / sales
1.7×

Cheaper than 57% of US stocks

Price / book
0.8×

Cheaper than 77% of US stocks

EV / EBITDA
−13.8×

Cheaper than 87% of US stocks

Growth & margins
Revenue growth (YoY)
4.3%

Higher than 39% of US stocks

Earnings growth (YoY)
4.3%

Higher than 42% of US stocks

Gross margin
48.9%

Higher than 62% of US stocks

Operating margin
−15.3%

Higher than 24% of US stocks

Net margin
−12.4%

Higher than 18% of US stocks

Returns & dividend
Return on equity
−5.9%

Higher than 38% of US stocks

Return on assets
−5.5%

Higher than 31% of US stocks

Dividend yield

Bars mark the percentile across the ~4,600 US stocks Ticker Nerd covers, among those reporting the figure.

Peers

OPK vs competitors

The nearest names by industry and size, scored by the same model — like for like.

Its peer group, ranked by the same modelDiagnostics & Research
CompanyMarket capTKN rank
OPKOPKO Health, Inc.$985.2M
79
CSTLCastle Biosciences, Inc.$817.3M
77
PSNLPersonalis, Inc.$1.3B
55
WGSGeneDx Holdings Corp.$1.9B
39
NEONeoGenomics, Inc.$2.0B
78
FLGTFulgent Genetics, Inc.$470.0M
61
CDNACareDx, Inc.$2.2B
99
Market Radar

This page is one stock. Monday covers all of them.

Computed off the Friday close and sent before the US open.

Market Radar reports the week’s largest rank changes across roughly 4,600 US stocks, the factor behind each one, and where the market went. OPK appears on the weeks it earns a place.

Free, every Monday. Unsubscribe any time.

News

Latest OPK news & analysis

Why Opko Health Stock Surged by 33% on Tuesday

The Motley Fool · 28 July 2026positive

Opko Health's stock surged 33% after the company reported a substantial narrowing of its net loss and raised its full-year revenue guidance.

Why it matters — OPK watchers would care because narrowing losses and higher revenue guidance signal potential improvement in the company's financial performance.

OPKO Health Stock Up as Q2 Earnings & Revenues Beat Estimates

Zacks Investment Research · 28 July 2026positive

OPKO Health beat Q2 estimates, with pharmaceutical growth, Nicoya income, and lower costs narrowing losses and lifting shares pre-market.

Why it matters — An OPK watcher would care because the company exceeded Q2 expectations and showed progress in narrowing losses through operational improvements.

OPKO Health, Inc. (OPK) Q2 2026 Earnings Call Transcript

Seeking Alpha · 28 July 2026neutral

Seeking Alpha published the transcript of OPKO Health's Q2 2026 earnings call.

Why it matters — Earnings call transcripts provide detailed insight into management's commentary on quarterly performance and future outlook.

Compared to Estimates, OPKO Health (OPK) Q2 Earnings: A Look at Key Metrics

Zacks Investment Research · 27 July 2026neutral

The article reviews OPKO Health's Q2 2026 earnings performance, comparing the company's top- and bottom-line results as well as key metrics against Wall Street estimates and year-ago figures.

Why it matters — OPK watchers would care because the comparison of key metrics to estimates and prior-year values offers insight into whether the company is meeting market expectations and how its performance trends are evolving.

OPKO Health (OPK) Reports Q2 Loss, Tops Revenue Estimates

Zacks Investment Research · 27 July 2026positive

OPKO Health reported a Q2 loss of $0.01 per share, narrower than the Zacks Consensus Estimate of a $0.08 loss and an improvement from the $0.19 loss a year earlier.

Why it matters — The smaller-than-expected quarterly loss signals improving financial performance for OPKO Health, which investors would watch as a measure of the company's operational progress.

FAQ

Frequently asked questions about OPK stock

What is the OPK stock price forecast for 2026-2027?

The 6 Wall Street analysts covering OPKO Health, Inc. have a median 12-month price target of $3, with estimates ranging from $3 to $8.5. These are third-party analyst estimates, not Ticker Nerd forecasts, and they are frequently wrong.

Is OPK stock a buy right now?

Of the 6 analysts covering OPKO Health, Inc., 4 rate it a Buy, 2 a Hold and 0 a Sell. Ticker Nerd's systematic factor model ranks OPKO Health, Inc. 79 out of 100 across roughly 4,600 US stocks as at 1 Aug 2026. None of this is personal advice — it does not consider your circumstances.

How does Ticker Nerd's model rank OPK?

As at 1 Aug 2026, OPKO Health, Inc. ranks 79 out of 100 on Ticker Nerd's systematic factor model — a percentile across roughly 4,600 US stocks, built from its factor families. Its strongest factor family is Growth (91 of 100).

Will OPK stock go up?

No one can know that. What the data says: the median 12-month target from 6 analysts implies +129.0% from the last close, and Ticker Nerd's factor model ranks OPKO Health, Inc. 79 out of 100 as at 1 Aug 2026. Analyst targets are third-party estimates and frequently wrong; none of this is personal advice.

What is the OPK stock forecast for 2030?

No analyst covering OPKO Health, Inc. publishes a 2030 price target — Wall Street targets run 12 to 18 months out. Sites quoting a 2030 price for OPK are extrapolating price history, which says nothing about the business. The furthest attributed numbers are the current analyst targets: $3 to $8.5 over the next 12 months.

How has OPK stock performed over the past year?

OPKO Health, Inc. returned +10.1% over the 12 months to 3 Aug 2026, with dividends reinvested. Past performance does not indicate future returns.

What does OPKO Health, Inc. do?

OpKO Health Inc. is a multinational biopharmaceutical and diagnostics company operating through two primary segments: Pharmaceuticals and Diagnostics.

What is the latest news on OPK?

The most recent item we track (The Motley Fool, 28 July 2026): "Why Opko Health Stock Surged by 33% on Tuesday". Opko Health's stock surged 33% after the company reported a substantial narrowing of its net loss and raised its full-year revenue guidance.

Company

About OPKO Health, Inc.

OpKO Health Inc. is a multinational biopharmaceutical and diagnostics company operating through two primary segments: Pharmaceuticals and Diagnostics. In the Pharmaceuticals segment, it develops and commercializes therapies such as Rayaldee, FDA-approved for treating secondary hyperparathyroidism in adults with chronic kidney disease and vitamin D insufficiency, and Somatrogon (hGH-CTP), approved in over 50 markets for growth hormone deficiency in children and adolescents. The company advances multispecific therapies targeting cancers and infectious diseases, partnering with leading pharmaceutical firms to deliver next-generation solutions for serious conditions across global markets. Its Diagnostics segment, primarily through BioReference Health, LLC, provides comprehensive clinical laboratory testing services, including the 4Kscore prostate cancer test, serving physicians, hospitals, clinics, and healthcare facilities nationwide with a network of labs. Founded in 1991 and headquartered in Miami, Florida, OpKO Health Inc. focuses on improving patient outcomes in healthcare and biopharmaceutical sectors.

CEO Dr. Phillip Frost M.D., Ph.D. · 2,275 employees · United States · https://www.opko.com