OPKOPKHealthcare · Diagnostics & Research

OPK Stock Forecast: OPKO Health, Inc. Price Predictions for 2026-2027

Last close, 1 Sept 2026
$1.52
+3.40% on the day

The 6 Wall Street analysts covering OPKO Health, Inc. hold a median 12-month price target of $3 — +97.4% from the last close. Ticker Nerd's systematic factor model, run across ~4,600 US stocks, ranks it 75 of 100 as at 31 Aug 2026 — inside the top quartile. Here, the model and the Street point the same way.

Market cap
$1.1B
Ticker Nerd rank
75 / 100
Median analyst target
$3.00
Analysts covering
6
Revenue$163.6M+4.3% y/y
Operating income−$25.0M
Net income−$8.4M
Free cash flow−$46.5M
Quarterly, 8 quarters to 30 June 2026 · latest quarter's figure shown
Total return, dividends reinvested
1W
+2.0%
1M
+15.2%
YTD
+20.6%
1Y
+10.1%
From 52W high
−7.9%
From 52W low
+38.2%
$1.10
$1.65
52-week range, adjusted closes · the dot is the last close
Ticker Nerd rank

OPK stock analysis: one number for the whole business

Consensus tells you what everyone already believes. The model scores OPKO Health, Inc. on its factor families — the same systematic rank behind the Ticker Nerd portfolio.

Where the model ranks itAs at 31 Aug 2026
75 / 100

Percentile across ~4,600 US stocks on Ticker Nerd’s systematic factor model. Higher is better. How the model is built and tested

Growth
91
Revisions
88
Issuance
77
Accruals
57
Volatility
53
Momentum
53
Quality
46
Size
44
Value
29

Growth (91): Sales and profits are climbing, and climbing faster than before.

Value (29): The shares cost a lot relative to the profits and assets behind them.

Built and run by Aslam Ghouse, an ex-Goldman Sachs quant trader with fourteen years in markets.

Wall Street

OPK stock forecast 2026-2027: analyst price targets & predictions

The bullish and bearish analyst opinions on OPK, reported as data — targets and ratings, the market's view beside the model's.

Share price and the analyst range, 12 monthsAdjusted close, US dollars
$0.00$2.00$4.00$6.00$8.00Oct 25Jan 26Apr 26Jul 26OPKHigh $8.50Median $3.00Low $3.00

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Data provided by Twelve Data

What Wall Street says6 analysts
4 Buy2 Hold0 Sell
Low $3.00Median $3.00High $8.50

The green dot is the last close — the median target sits +97.4% from it.

Recent analyst actionsNewest first
DateFirmActionRatingTarget
29 Apr 2026Barrington ResearchDowngradeMarket Perform
2 Mar 2026Barrington ResearchMaintainsOutperform
20 Nov 2025JP MorganInitiatesNeutral
31 Oct 2025JefferiesDowngradeHold
30 Oct 2025Barrington ResearchMaintainsOutperform
1 May 2025Barrington ResearchMaintainsOutperform
25 Apr 2025JP MorganInitiatesNeutral
7 Apr 2025HC Wainwright & Co.ReiteratesBuy
19 Mar 2025HC Wainwright & Co.ReiteratesBuy
12 Mar 2025Barrington ResearchMaintainsOutperform
12 Mar 2025HC Wainwright & Co.ReiteratesBuy
3 Mar 2025HC Wainwright & Co.ReiteratesBuy
28 Feb 2025Barrington ResearchMaintainsOutperform
8 Jan 2025HC Wainwright & Co.MaintainsBuy
8 Nov 2024Barrington ResearchMaintainsOutperform
26 Sept 2024HC Wainwright & Co.ReiteratesBuy
20 Sept 2024Barrington ResearchMaintainsOutperform
17 Sept 2024HC Wainwright & Co.ReiteratesBuy
17 Sept 2024Piper SandlerReiteratesOverweight
8 Aug 2024Barrington ResearchMaintainsOutperform

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Market Radar

This page is one stock. Monday covers all of them.

Computed off the Friday close and sent before the US open.

Market Radar reports the week’s largest rank changes across roughly 4,600 US stocks, the factor behind each one, and where the market went. OPK appears on the weeks it earns a place.

Free, every Monday. Unsubscribe any time.

Performance

OPK vs the S&P 500

Both lines are total return — dividends reinvested — so the comparison is honest on both sides.

Over the twelve months to 1 Sept 2026, OPKO Health, Inc. returned +10.1% against +19.4% for the S&P 500, dividends included.

OPK vs S&P 500, last 12 monthsTotal return, rebased to 100
8090100110120Oct 25Jan 26Apr 26Jul 26OPKS&P 500

Download this chart as an image — free to reuse; link this page as the source.

Data provided by Twelve Data

Estimates

OPK analyst estimate revisions

Not the forecast itself — the direction analysts are revising it. Revision direction is one of the model's factor families.

Which way the estimates are movingNext fiscal year
Analysts raising
1
Analysts cutting
0
Fundamentals

OPKO Health, Inc. (OPK) financial data

A margin means little on its own. Each bar marks where the figure sits across the whole US universe we score.

Valuation
Trailing P/E
−5.1×

Cheaper than 90% of US stocks

Price / sales
1.9×

Cheaper than 55% of US stocks

Price / book
1.0×

Cheaper than 76% of US stocks

EV / EBITDA
−15.3×

Cheaper than 87% of US stocks

Growth & margins
Revenue growth (YoY)
4.3%

Higher than 37% of US stocks

Earnings growth (YoY)
4.3%

Higher than 41% of US stocks

Gross margin
48.9%

Higher than 61% of US stocks

Operating margin
−15.3%

Higher than 23% of US stocks

Net margin
−12.4%

Higher than 19% of US stocks

Returns & dividend
Return on equity
−5.9%

Higher than 39% of US stocks

Return on assets
−5.5%

Higher than 31% of US stocks

Dividend yield

Bars mark the percentile across the ~4,600 US stocks Ticker Nerd covers, among those reporting the figure.

Key statistics

OPKO Health, Inc. (OPK) statistics: revenue, profit & scale

The headline figures, each with its date. Every row carries its own link — cite it straight from here.

  • OPKO Health, Inc. has a market value of $1.1B and an enterprise value of $1.2B.

  • Revenue in the twelve months to 30 June 2026: $587.9M. The latest quarter grew 4.3% year on year.

  • Net income over the same four quarters: −$72.9M, a −12.4% net margin.

  • Diluted earnings per share, trailing twelve months: $−0.09.

  • Free cash flow in the twelve months to 30 June 2026: −$134.0M, after $10.6M of capital spending.

  • OPKO Health, Inc. spent $46.6M on share buybacks in the twelve months to 30 June 2026.

  • Shares outstanding: 746.0M.

  • Trailing P/E: −5.1×; forward P/E: −5.5× — the forward figure prices analyst consensus estimates, not reported earnings.

  • OPKO Health, Inc. employs 2,275 people $258K of revenue per employee.

Statement figures: company filings via Twelve Data, four quarters to 30 June 2026 · market figures as at 1 Sept 2026

Data provided by Twelve Data

Peers

OPK vs competitors

The nearest names by industry and size, scored by the same model — like for like.

Its peer group, ranked by the same modelDiagnostics & Research
CompanyMarket capTKN rank
OPKOPKO Health, Inc.$1.1B
75
CSTLCastle Biosciences, Inc.$964.1M
87
FRNMFreenome, Inc.$1.6B
34
PSNLPersonalis, Inc.$1.8B
42
FLGTFulgent Genetics, Inc.$550.1M
44
NEONeoGenomics, Inc.$2.3B
75
WGSGeneDx Holdings Corp.$2.4B
43

Look up any of the roughly 4,600 stocks we score.

The rank is the raw material. Whether the rules would actually own OPKO Health, Inc. — and when they’d sell — is the membership. See the Ticker Nerd 20 →

News

Latest OPK news & analysis

Why Is OPKO Health (OPK) Down 9.7% Since Last Earnings Report?

Zacks Investment Research · 26 Aug 2026negative

OPKO Health (OPK) reported earnings 30 days ago, and its stock is down 9.7% since that earnings report. The item notes that the company's next move for the stock is being watched.

Why it matters — An OPK watcher would care because the stock has declined notably in the month following the latest earnings report, with attention now on what comes next for the company.

Here's Why You Should Retain OPK Stock in Your Portfolio for Now

Zacks Investment Research · 24 Aug 2026positive

Zacks Investment Research advises investors to retain OPKO Health stock, citing a growth outlook supported by RAYALDEE, strategic partnerships, BioReference restructuring, and multiple pipeline catalysts.

Why it matters — OPK watchers would care because the report highlights the company's current product, partnerships, restructuring, and pipeline as factors supporting its outlook.

OPK Raises $125 Million Against Royalties: What Investors Should Know

Zacks Investment Research · 19 Aug 2026positive

OPKO Health secured $125 million in royalty-backed financing, providing non-dilutive capital while retaining long-term exposure to mazdutide growth in China.

Why it matters — The financing adds capital without diluting existing shareholders while keeping OPK's upside from mazdutide in China intact.

Is OPK Worth Buying as Valuation Meets Improving Business Trends?

Zacks Investment Research · 19 Aug 2026neutral

A Zacks Investment Research article examines whether OPKO Health is worth buying as its valuation meets improving business trends, noting the company pairs a discounted forward sales multiple with narrowing losses and partnership support, while early-stage clinical risk keeps the investment case balanced.

Why it matters — OPK watchers would care because the analysis weighs improving financial and partnership trends against ongoing early-stage clinical risk in assessing the company's outlook.

OPK Climbs 12.4% in the Past Month: Can the Stock Rally Keep Going?

Zacks Investment Research · 19 Aug 2026neutral

OPKO Health's stock rose 12.4% over the past month, a gain the report attributes to narrower losses and improved margins. The report also notes that profitability and clinical execution remain key risks going forward.

Why it matters — The monthly stock gain and improved financial metrics offer OPK watchers a current snapshot of the company's performance, while the highlighted risks of profitability and clinical execution point to factors likely to shape its outlook.

FAQ

Frequently asked questions about OPK stock

What is the OPK stock price forecast for 2026-2027?

The 6 Wall Street analysts covering OPKO Health, Inc. have a median 12-month price target of $3, with estimates ranging from $3 to $8.5. These are third-party analyst estimates, not Ticker Nerd forecasts, and they are frequently wrong.

Is OPK stock a buy right now?

Of the 6 analysts covering OPKO Health, Inc., 4 rate it a Buy, 2 a Hold and 0 a Sell. Ticker Nerd's systematic factor model ranks OPKO Health, Inc. 75 out of 100 across roughly 4,600 US stocks as at 31 Aug 2026. None of this is personal advice — it does not consider your circumstances.

How does Ticker Nerd's model rank OPK?

As at 31 Aug 2026, OPKO Health, Inc. ranks 75 out of 100 on Ticker Nerd's systematic factor model — a percentile across roughly 4,600 US stocks, built from its factor families. Its strongest factor family is Growth (91 of 100).

Will OPK stock go up?

No one can know that. What the data says: the median 12-month target from 6 analysts implies +97.4% from the last close, and Ticker Nerd's factor model ranks OPKO Health, Inc. 75 out of 100 as at 31 Aug 2026. Analyst targets are third-party estimates and frequently wrong; none of this is personal advice.

What is the OPK stock forecast for 2030?

No analyst covering OPKO Health, Inc. publishes a 2030 price target — Wall Street targets run 12 to 18 months out. Sites quoting a 2030 price for OPK are extrapolating price history, which says nothing about the business. The furthest attributed numbers are the current analyst targets: $3 to $8.5 over the next 12 months.

How has OPK stock performed over the past year?

OPKO Health, Inc. returned +10.1% over the 12 months to 1 Sept 2026, with dividends reinvested. Past performance does not indicate future returns.

What does OPKO Health, Inc. do?

OPKO Health, Inc. is a diversified healthcare company focused on diagnostics and pharmaceuticals.

What is the latest news on OPK?

The most recent item we track (Zacks Investment Research, 26 Aug 2026): "Why Is OPKO Health (OPK) Down 9.7% Since Last Earnings Report?". OPKO Health (OPK) reported earnings 30 days ago, and its stock is down 9.7% since that earnings report. The item notes that the company's next move for the stock is being watched.

Company

About OPKO Health, Inc.

OPKO Health, Inc. is a diversified healthcare company focused on diagnostics and pharmaceuticals. Through its Diagnostics segment, the company provides clinical laboratory and genetic testing services, including BioReference Health and specialized assays used in disease detection, monitoring, and patient management. Its Pharmaceutical segment markets approved therapies and supports development programs across areas such as kidney disease, hormone-related disorders, oncology, and infectious diseases. OPKO Health also works with commercial partners and maintains manufacturing, supply, and research activities across several international markets. The company plays a broad role in the healthcare market by combining testing services, marketed medicines, and pipeline assets within a single operating platform. OPKO Health, Inc. is headquartered in Miami, Florida.

CEO Dr. Phillip Frost M.D., Ph.D. · 2,275 employees · United States · https://www.opko.com