OPKOPKHealthcare · Diagnostics & Research

OPK Stock Forecast: OPKO Health, Inc. Price Predictions for 2026-2027

Last close, 4 Nov 2026
$1.77
+2.91% on the day

The 6 Wall Street analysts covering OPKO Health, Inc. hold a median 12-month price target of $3 — +69.5% from the last close. Ticker Nerd's systematic factor model, run across ~4,600 US stocks, ranks it 70 of 100 as at 4 Nov 2026 — in the upper half. Here, the model and the Street point the same way.

Market cap
$1.3B
Ticker Nerd rank
70/ 100
Median analyst target
$3.00
Analysts covering
6
Revenue$163.6M+4.3% y/y
Operating income−$25.0M
Net income−$8.4M
Free cash flow−$46.5M
Quarterly, 8 quarters to 30 June 2026 · latest quarter's figure shown
Total return, dividends reinvested
1W
+9.3%
1M
+13.5%
YTD
+40.5%
1Y
+27.3%
From 52W high
0.0%
From 52W low
+60.9%
$1.10
$1.77
52-week range, adjusted closes · the dot is the last close
Ticker Nerd rank

OPK stock analysis: one number for the whole business

Consensus tells you what everyone already believes. The model scores OPKO Health, Inc. on its factor families — the same systematic rank behind the Ticker Nerd portfolio.

Where the model ranks itAs at 4 Nov 2026
70/ 100

Percentile across ~4,600 US stocks on Ticker Nerd’s systematic factor model. Higher is better. How the model is built and tested

Growth
90
Issuance
77
Volatility
77
Momentum
73
Accruals
57
Revisions
57
Quality
43
Size
40
Value
30

Growth (90): Sales and profits are climbing, and climbing faster than before.

Value (30): The shares cost a lot relative to the profits and assets behind them.

Built and run by Aslam Ghouse, an ex-Goldman Sachs systematic trader with 15+ years in markets.

Wall Street

OPK stock forecast 2026-2027: analyst price targets & predictions

The bullish and bearish analyst opinions on OPK, reported as data — targets and ratings, the market's view beside the model's.

Share price and the analyst range, 12 monthsAdjusted close, US dollars
$0.00$2.00$4.00$6.00$8.00Jan 26Apr 26Jul 26Oct 26OPKHigh $8.50Median $3.00Low $2.25

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Data provided by Twelve Data

What Wall Street says6 analysts
5 Buy1 Hold0 Sell
Low $2.25Median $3.00High $8.50

The green dot is the last close — the median target sits +69.5% from it.

Recent analyst actionsNewest first
DateFirmActionRatingTarget
16 Oct 2026Barrington ResearchUpgradeOutperform—
16 Oct 2026Piper SandlerReiteratesOverweight$3.00 → $4.00
29 Apr 2026Barrington ResearchDowngradeMarket Perform—
29 Apr 2026Barrington ResearchDowngradeMarket Perform—
2 Mar 2026Barrington ResearchMaintainsOutperform—
20 Nov 2025JP MorganInitiatesNeutral—
31 Oct 2025JefferiesDowngradeHold—
30 Oct 2025Barrington ResearchMaintainsOutperform—
1 May 2025Barrington ResearchMaintainsOutperform—
25 Apr 2025JP MorganInitiatesNeutral—
7 Apr 2025HC Wainwright & Co.ReiteratesBuy—
19 Mar 2025HC Wainwright & Co.ReiteratesBuy—
12 Mar 2025Barrington ResearchMaintainsOutperform—
12 Mar 2025HC Wainwright & Co.ReiteratesBuy—
3 Mar 2025HC Wainwright & Co.ReiteratesBuy—
28 Feb 2025Barrington ResearchMaintainsOutperform—
8 Jan 2025HC Wainwright & Co.MaintainsBuy—
8 Nov 2024Barrington ResearchMaintainsOutperform—
26 Sept 2024HC Wainwright & Co.ReiteratesBuy—
20 Sept 2024Barrington ResearchMaintainsOutperform—

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Market Radar

This page is one stock. Monday covers all of them.

OPK appears in the Radar on the weeks it earns a place.

  • Market Radar, every Monday: the week's biggest rank moves across ~4,600 US stocks, and the reason for each.
  • The AI build-out map, free: every AI company we track, part by part, and one part in full with each verdict.

Free. Unsubscribe any time.

The AI build-out map
PDF
  • AI cloud capacity

    MSFTAMZNGOOGLORCL

  • AI chips

    NVDAAVGOAMDMU

  • AI networking and serversIn full

    ANETDELLLITECRDO

  • Data centre power

    VRTCEGGEVVST

Performance

OPK vs the S&P 500

Both lines are total return — dividends reinvested — so the comparison is honest on both sides.

Over the twelve months to 4 Nov 2026, OPKO Health, Inc. returned +27.3% against +14.8% for the S&P 500, dividends included.

OPK vs S&P 500, last 12 monthsTotal return, rebased to 100
8090100110120130Jan 26Apr 26Jul 26Oct 26OPKS&P 500

Download this chart as an image — free to reuse; link this page as the source.

Data provided by Twelve Data

Estimates

OPK analyst estimate revisions

Not the forecast itself — the direction analysts are revising it. Revision direction is one of the model's factor families.

Which way the estimates are movingThis fiscal year
Analysts raising
1
Analysts cutting
0
Fundamentals

OPKO Health, Inc. (OPK) financial data

A margin means little on its own. Each bar marks where the figure sits across the whole US universe we score.

Valuation
Trailing P/E
−5.8×

Cheaper than 91% of US stocks

Price / sales
2.2×

Cheaper than 49% of US stocks

Price / book
1.1×

Cheaper than 67% of US stocks

EV / EBITDA
−17.7×

Cheaper than 89% of US stocks

Growth & margins
Revenue growth (YoY)
4.3%

Higher than 38% of US stocks

Earnings growth (YoY)
4.3%

Higher than 42% of US stocks

Gross margin
48.9%

Higher than 60% of US stocks

Operating margin
−15.3%

Higher than 23% of US stocks

Net margin
−12.4%

Higher than 18% of US stocks

Returns & dividend
Return on equity
−5.9%

Higher than 39% of US stocks

Return on assets
−5.5%

Higher than 31% of US stocks

Dividend yield
0.0%

Higher than 1% of US dividend payers

Bars mark the percentile across the ~4,600 US stocks Ticker Nerd covers, among those reporting the figure.

Key statistics

OPKO Health, Inc. (OPK) statistics: revenue, profit & scale

The headline figures, each with its date. Every row carries its own link — cite it straight from here.

  • OPKO Health, Inc. has a market value of $1.3B and an enterprise value of $1.4B.

  • Revenue in the twelve months to 30 June 2026: $587.9M. The latest quarter grew 4.3% year on year.

  • Net income over the same four quarters: −$72.9M, a −12.4% net margin.

  • Diluted earnings per share, trailing twelve months: $−0.09.

  • Free cash flow in the twelve months to 30 June 2026: −$134.0M, after $10.6M of capital spending.

  • OPKO Health, Inc. spent $46.6M on share buybacks in the twelve months to 30 June 2026.

  • Shares outstanding: 746.0M.

  • Trailing P/E: −5.8×; forward P/E: −5.0× — the forward figure prices analyst consensus estimates, not reported earnings.

  • Forward dividend yield: 0.00%, paying out 0% of earnings.

  • OPKO Health, Inc. employs 2,275 people — $258K of revenue per employee.

Statement figures: company filings via Twelve Data, four quarters to 30 June 2026 · market figures as at 3 Nov 2026

Data provided by Twelve Data

Peers

OPK vs competitors

The nearest names by industry and size, scored by the same model — like for like.

Its peer group, ranked by the same modelDiagnostics & Research
CompanyMarket capTKN rank
OPKOPKO Health, Inc.$1.3B70
FRNMFreenome, Inc.$1.2B28
PSNLPersonalis, Inc.$1.7B47
CSTLCastle Biosciences, Inc.$1.0B90
WGSGeneDx Holdings Corp.$2.1B48
NEONeoGenomics, Inc.$2.2B70
MYGNMyriad Genetics, Inc.$562.9M58

Look up any of the roughly 4,600 stocks we score.

The rank is the raw material. Whether the rules would actually own OPKO Health, Inc. — and when they’d sell — is the membership. See the Ticker Nerd 20 →

News

Latest OPK news & analysis

What OPKO Health (OPK) Said on Its Q3 Earnings Call

MarketBeat · 5 Nov 2026positive

OPKO Health reported 16% growth in third-quarter revenue from continuing operations. On its earnings call, the company outlined plans to focus on drug development and pharmaceutical products following its proposed sale of BioReference assets to Labcorp.

Why it matters — The update highlights OPKO’s revenue growth and its planned business focus after the proposed BioReference asset sale.

OPKO Health, Inc. (OPK) Q3 2026 Earnings Call Transcript

Seeking Alpha · 5 Nov 2026neutral

Seeking Alpha published a transcript of OPKO Health, Inc.’s Q3 2026 earnings call. The excerpt provides no details about the discussion.

Why it matters — The transcript is a source for OPK watchers seeking information from the company’s quarterly earnings call, but the excerpt does not disclose its contents.

OPKO Health (OPK) Reports Q3 Loss, Misses Revenue Estimates

Zacks Investment Research · 5 Nov 2026neutral

OPKO Health reported a third-quarter loss of $0.05 per share, compared with the Zacks consensus estimate of a $0.07 loss. The result compares with earnings of $0.03 per share a year earlier.

Why it matters — OPK watchers may note the quarterly per-share loss was smaller than the consensus estimate, while the company reported earnings in the year-ago quarter.

OPKO Health Reports Third Quarter 2026 Business Highlights and Financial Results

GlobeNewsWire · 4 Nov 2026neutral

OPKO Health reported third-quarter 2026 business highlights and financial results. The company said it entered into an agreement with Labcorp to sell substantially all remaining BioReference diagnostic operations.

Why it matters — The reported agreement concerns OPKO’s remaining BioReference diagnostic operations, a significant business update for investors following the company.

OPKO Health to Report Third Quarter 2026 Financial Results on November 4, 2026

GlobeNewsWire · 28 Oct 2026neutral

OPKO Health announced it will report third-quarter 2026 operating and financial results on November 4, 2026. Senior management will host a conference call and webcast at 4:30 p.m. ET to provide a business update and discuss results and financial guidance.

Why it matters — OPK watchers can use the scheduled report and management discussion to follow the company’s quarterly results and guidance.

FAQ

Frequently asked questions about OPK stock

What is the OPK stock price forecast for 2026-2027?

The 6 Wall Street analysts covering OPKO Health, Inc. have a median 12-month price target of $3, with estimates ranging from $2.25 to $8.5. These are third-party analyst estimates, not Ticker Nerd forecasts, and they are frequently wrong.

Is OPK stock a buy right now?

Of the 6 analysts covering OPKO Health, Inc., 5 rate it a Buy, 1 a Hold and 0 a Sell. Ticker Nerd's systematic factor model ranks OPKO Health, Inc. 70 out of 100 across roughly 4,600 US stocks as at 4 Nov 2026. None of this is personal advice — it does not consider your circumstances.

How does Ticker Nerd's model rank OPK?

As at 4 Nov 2026, OPKO Health, Inc. ranks 70 out of 100 on Ticker Nerd's systematic factor model — a percentile across roughly 4,600 US stocks, built from its factor families. Its strongest factor family is Growth (90 of 100).

Will OPK stock go up?

No one can know that. What the data says: the median 12-month target from 6 analysts implies +69.5% from the last close, and Ticker Nerd's factor model ranks OPKO Health, Inc. 70 out of 100 as at 4 Nov 2026. Analyst targets are third-party estimates and frequently wrong; none of this is personal advice.

What is the OPK stock forecast for 2030?

No analyst covering OPKO Health, Inc. publishes a 2030 price target — Wall Street targets run 12 to 18 months out. Sites quoting a 2030 price for OPK are extrapolating price history, which says nothing about the business. The furthest attributed numbers are the current analyst targets: $2.25 to $8.5 over the next 12 months.

How has OPK stock performed over the past year?

OPKO Health, Inc. returned +27.3% over the 12 months to 4 Nov 2026, with dividends reinvested. Past performance does not indicate future returns.

What does OPKO Health, Inc. do?

OPKO Health, Inc. is a diversified healthcare company focused on diagnostics and pharmaceuticals.

What is the latest news on OPK?

The most recent item we track (MarketBeat, 5 Nov 2026): "What OPKO Health (OPK) Said on Its Q3 Earnings Call". OPKO Health reported 16% growth in third-quarter revenue from continuing operations. On its earnings call, the company outlined plans to focus on drug development and pharmaceutical products following its proposed sale of BioReference assets to Labcorp.

Company

About OPKO Health, Inc.

OPKO Health, Inc. is a diversified healthcare company focused on diagnostics and pharmaceuticals. Through its Diagnostics segment, the company provides clinical laboratory and genetic testing services, including BioReference Health and specialized assays used in disease detection, monitoring, and patient management. Its Pharmaceutical segment markets approved therapies and supports development programs across areas such as kidney disease, hormone-related disorders, oncology, and infectious diseases. OPKO Health also works with commercial partners and maintains manufacturing, supply, and research activities across several international markets. The company plays a broad role in the healthcare market by combining testing services, marketed medicines, and pipeline assets within a single operating platform. OPKO Health, Inc. is headquartered in Miami, Florida.

CEO Dr. Phillip Frost M.D., Ph.D. · 2,275 employees · United States · https://www.opko.com