CSTLCSTLHealthcare · Diagnostics & Research

CSTL Stock Forecast: Castle Biosciences, Inc. Price Predictions for 2026-2027

Last close, 3 Sept 2026
$33
−2.30% on the day

The 9 Wall Street analysts covering Castle Biosciences, Inc. hold a median 12-month price target of $44 — +34.8% from the last close. Ticker Nerd's systematic factor model, run across ~4,600 US stocks, ranks it 88 of 100 as at 2 Sept 2026 — inside the top quartile. Here, the model and the Street point the same way.

Market cap
$1.0B
Ticker Nerd rank
88 / 100
Median analyst target
$44
Analysts covering
9
Revenue$103.5M+20.1% y/y
Operating income−$3.1M
Net income−$2.1M
Free cash flow$6.6M
Quarterly, 8 quarters to 30 June 2026 · latest quarter's figure shown
Total return, dividends reinvested
1W
−4.7%
1M
+7.4%
YTD
−16.1%
1Y
+40.7%
From 52W high
−24.1%
From 52W low
+79.9%
$18
$43
52-week range, adjusted closes · the dot is the last close
Ticker Nerd rank

CSTL stock analysis: one number for the whole business

Consensus tells you what everyone already believes. The model scores Castle Biosciences, Inc. on its factor families — the same systematic rank behind the Ticker Nerd portfolio.

Where the model ranks itAs at 2 Sept 2026
88 / 100

Percentile across ~4,600 US stocks on Ticker Nerd’s systematic factor model. Higher is better. How the model is built and tested

Momentum
88
Quality
79
Revisions
78
Volatility
76
Accruals
72
Value
72
Issuance
49
Size
45
Growth
40

Momentum (88): The shares have been drifting up relative to others.

Growth (40): Sales and profits are flat, shrinking, or growing more slowly than they were.

Built and run by Aslam Ghouse, an ex-Goldman Sachs quant trader with fourteen years in markets.

Wall Street

CSTL stock forecast 2026-2027: analyst price targets & predictions

The bullish and bearish analyst opinions on CSTL, reported as data — targets and ratings, the market's view beside the model's.

Share price and the analyst range, 12 monthsAdjusted close, US dollars
$20$30$40$50$60Oct 25Jan 26Apr 26Jul 26CSTLHigh $57Median $44Low $35

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Data provided by Twelve Data

What Wall Street says9 analysts
9 Buy0 Hold0 Sell
Low $35Median $44High $57

The green dot is the last close — the median target sits +34.8% from it.

Recent analyst actionsNewest first
DateFirmActionRatingTarget
3 Aug 2026BTIGMaintainsBuy$40$44
25 June 2026Roth CapitalInitiatesBuy$40
25 June 2026Roth CapitalInitiatesBuy
13 May 2026BTIGMaintainsBuy
7 May 2026BairdMaintainsOutperform
20 Apr 2026Canaccord GenuityMaintainsBuy
27 Feb 2026BairdMaintainsOutperform
26 Jan 2026GuggenheimMaintainsBuy
12 Jan 2026Lake StreetMaintainsBuy
5 Jan 2026GuggenheimMaintainsBuy
22 Dec 2025Canaccord GenuityMaintainsBuy
12 Dec 2025BTIGMaintainsBuy
5 Nov 2025BTIGMaintainsBuy
4 Nov 2025BairdMaintainsOutperform
9 Sept 2025Canaccord GenuityMaintainsBuy
21 May 2025ScotiabankMaintainsSector Outperform
6 May 2025Canaccord GenuityMaintainsBuy
6 May 2025Lake StreetMaintainsBuy
28 Feb 2025BairdMaintainsOutperform
2 Jan 2025Stephens & Co.ReiteratesOverweight

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Market Radar

This page is one stock. Monday covers all of them.

Computed off the Friday close and sent before the US open.

Market Radar reports the week’s largest rank changes across roughly 4,600 US stocks, the factor behind each one, and where the market went. CSTL appears on the weeks it earns a place.

Free, every Monday. Unsubscribe any time.

Performance

CSTL vs the S&P 500

Both lines are total return — dividends reinvested — so the comparison is honest on both sides.

Over the twelve months to 3 Sept 2026, Castle Biosciences, Inc. returned +40.7% against +21.4% for the S&P 500, dividends included.

CSTL vs S&P 500, last 12 monthsTotal return, rebased to 100
80100120140160180200Oct 25Jan 26Apr 26Jul 26CSTLS&P 500

Download this chart as an image — free to reuse; link this page as the source.

Data provided by Twelve Data

Estimates

CSTL analyst estimate revisions

Not the forecast itself — the direction analysts are revising it. Revision direction is one of the model's factor families.

Which way the estimates are movingNext fiscal year
Analysts raising
6
Analysts cutting
2
Fundamentals

Castle Biosciences, Inc. (CSTL) financial data

A margin means little on its own. Each bar marks where the figure sits across the whole US universe we score.

Valuation
Trailing P/E
30.5×

Cheaper than 26% of US stocks

Price / sales
2.9×

Cheaper than 43% of US stocks

Price / book
2.2×

Cheaper than 43% of US stocks

EV / EBITDA
−47.9×

Cheaper than 94% of US stocks

Growth & margins
Revenue growth (YoY)
20.1%

Higher than 70% of US stocks

Earnings growth (YoY)
20.1%

Higher than 59% of US stocks

Gross margin
77.1%

Higher than 89% of US stocks

Operating margin
−3.0%

Higher than 29% of US stocks

Net margin
−5.4%

Higher than 23% of US stocks

Returns & dividend
Return on equity
−4.2%

Higher than 40% of US stocks

Return on assets
−1.4%

Higher than 39% of US stocks

Dividend yield

Bars mark the percentile across the ~4,600 US stocks Ticker Nerd covers, among those reporting the figure.

Key statistics

Castle Biosciences, Inc. (CSTL) statistics: revenue, profit & scale

The headline figures, each with its date. Every row carries its own link — cite it straight from here.

  • Castle Biosciences, Inc. has a market value of $1.0B and an enterprise value of $791.4M.

  • Revenue in the twelve months to 30 June 2026: $357.3M. The latest quarter grew 20.1% year on year.

  • Net income over the same four quarters: −$19.4M, a −5.4% net margin.

  • Diluted earnings per share, trailing twelve months: $−0.66.

  • Free cash flow in the twelve months to 30 June 2026: −$489K.

  • Shares outstanding: 30.5M.

  • Trailing P/E: 30.5×; forward P/E: −33.8× — the forward figure prices analyst consensus estimates, not reported earnings.

  • Castle Biosciences, Inc. employs 1,002 people $357K of revenue per employee.

Statement figures: company filings via Twelve Data, four quarters to 30 June 2026 · market figures as at 3 Sept 2026

Data provided by Twelve Data

Peers

CSTL vs competitors

The nearest names by industry and size, scored by the same model — like for like.

Its peer group, ranked by the same modelDiagnostics & Research
CompanyMarket capTKN rank
CSTLCastle Biosciences, Inc.$1.0B
88
OPKOPKO Health, Inc.$1.3B
82
FLGTFulgent Genetics, Inc.$569.1M
43
FRNMFreenome, Inc.$1.7B
32
PSNLPersonalis, Inc.$1.8B
41
NEONeoGenomics, Inc.$2.2B
76
WGSGeneDx Holdings Corp.$2.5B
44

Look up any of the roughly 4,600 stocks we score.

The rank is the raw material. Whether the rules would actually own Castle Biosciences, Inc. — and when they’d sell — is the membership. See the Ticker Nerd 20 →

News

Latest CSTL news & analysis

Castle Biosciences, Inc. (CSTL) Is Up 15.46% in One Week: What You Should Know

Zacks Investment Research · 28 Aug 2026positive

The article from Zacks Investment Research notes that Castle Biosciences, Inc. (CSTL) rose 15.46% over the past week. The piece examines whether the company could be a top pick for momentum investors.

Why it matters — For those tracking CSTL, the piece highlights a notable one-week price gain and evaluates the stock's potential appeal to momentum-focused investors.

Does Castle Biosciences (CSTL) Have the Potential to Rally 31.46% as Wall Street Analysts Expect?

Zacks Investment Research · 25 Aug 2026positive

Zacks Investment Research reports that the consensus price target for Castle Biosciences (CSTL) suggests roughly 31.5% upside potential. The article notes that while this metric is not highly effective on its own, an upward trend in earnings estimate revisions could indicate near-term upside for the stock.

Why it matters — CSTL watchers would care because the piece highlights the consensus price target and recent upward earnings estimate revisions, which could signal improving analyst sentiment around the company.

Castle Biosciences to Participate in Upcoming Investor Conferences

PRNewsWire · 20 Aug 2026neutral

Castle Biosciences announced that its executive management is scheduled to present a company overview at Baird's 2026 Global Healthcare Conference on Tuesday, Sept. 15, 2026, at 10:50 a.m. The announcement was made by the company, which is listed on Nasdaq under the ticker CSTL.

Why it matters — Presenting at a major healthcare conference gives investors and analysts an opportunity to hear directly from Castle Biosciences' management about its business and strategy.

Castle Biosciences Approved for Dual Listing on Nasdaq Texas

PRNewsWire · 17 Aug 2026positive

Castle Biosciences announced it has been approved for a dual listing of its common stock on Nasdaq Texas, a new exchange headquartered in Dallas. The company will retain its primary listing on The Nasdaq Global Market, with the stock expected to begin trading on Nasdaq Texas under the existing ticker "CSTL."

Why it matters — This expands Castle's trading venues and increases its visibility and accessibility to investors through the new Nasdaq Texas exchange.

Castle Biosciences Raises Outlook as Melanoma, TissueCypher Tests Gain Traction

MarketBeat · 13 Aug 2026positive

Castle Biosciences reported continued momentum in its core diagnostic franchises during the second quarter. CFO Frank Stokes said the company raised its outlook by more than the amount of its reported beat.

Why it matters — A CSTL watcher would care because an outlook raise tied to core diagnostic momentum suggests strengthening performance in its key melanoma and tissue-based testing products.

FAQ

Frequently asked questions about CSTL stock

What is the CSTL stock price forecast for 2026-2027?

The 9 Wall Street analysts covering Castle Biosciences, Inc. have a median 12-month price target of $44, with estimates ranging from $35 to $57. These are third-party analyst estimates, not Ticker Nerd forecasts, and they are frequently wrong.

Is CSTL stock a buy right now?

Of the 9 analysts covering Castle Biosciences, Inc., 9 rate it a Buy, 0 a Hold and 0 a Sell. Ticker Nerd's systematic factor model ranks Castle Biosciences, Inc. 88 out of 100 across roughly 4,600 US stocks as at 2 Sept 2026. None of this is personal advice — it does not consider your circumstances.

How does Ticker Nerd's model rank CSTL?

As at 2 Sept 2026, Castle Biosciences, Inc. ranks 88 out of 100 on Ticker Nerd's systematic factor model — a percentile across roughly 4,600 US stocks, built from its factor families. Its strongest factor family is Momentum (88 of 100).

Will CSTL stock go up?

No one can know that. What the data says: the median 12-month target from 9 analysts implies +34.8% from the last close, and Ticker Nerd's factor model ranks Castle Biosciences, Inc. 88 out of 100 as at 2 Sept 2026. Analyst targets are third-party estimates and frequently wrong; none of this is personal advice.

What is the CSTL stock forecast for 2030?

No analyst covering Castle Biosciences, Inc. publishes a 2030 price target — Wall Street targets run 12 to 18 months out. Sites quoting a 2030 price for CSTL are extrapolating price history, which says nothing about the business. The furthest attributed numbers are the current analyst targets: $35 to $57 over the next 12 months.

How has CSTL stock performed over the past year?

Castle Biosciences, Inc. returned +40.7% over the 12 months to 3 Sept 2026, with dividends reinvested. Past performance does not indicate future returns.

What does Castle Biosciences, Inc. do?

Castle Biosciences Inc. is a molecular diagnostics company that develops and commercializes proprietary tests designed to support clinical decision-making.

What is the latest news on CSTL?

The most recent item we track (Zacks Investment Research, 28 Aug 2026): "Castle Biosciences, Inc. (CSTL) Is Up 15.46% in One Week: What You Should Know". The article from Zacks Investment Research notes that Castle Biosciences, Inc. (CSTL) rose 15.46% over the past week. The piece examines whether the company could be a top pick for momentum investors.

Company

About Castle Biosciences, Inc.

Castle Biosciences Inc. is a molecular diagnostics company that develops and commercializes proprietary tests designed to support clinical decision-making. The company focuses primarily on dermatologic cancers, including melanoma and cutaneous squamous cell carcinoma, while also serving gastroenterology, ophthalmology, and certain mental health applications. Its portfolio includes tests used to help assess risk, refine diagnosis, and guide treatment choices through clinically actionable genomic and molecular information. Castle Biosciences works with physicians, specialty clinics, hospitals, and health systems that rely on specialized testing to better manage complex diseases and personalize care. The company’s role in the market centers on translating laboratory science into practical tools that can improve how patients are evaluated and treated across several high-need medical areas.

CEO Mr. Derek J. Maetzold · 1,002 employees · United States · https://castlebiosciences.com