RYTMRYTMHealthcare · Biotechnology

RYTM Stock Forecast: Rhythm Pharmaceuticals, Inc. Price Predictions for 2026-2027

Last close, 14 Aug 2026
$115
−0.47% on the day

The 16 Wall Street analysts covering Rhythm Pharmaceuticals, Inc. hold a median 12-month price target of $145 — +25.6% from the last close. Ticker Nerd's systematic factor model, run across ~4,600 US stocks, ranks it 88 of 100 as at 14 Aug 2026 — inside the top quartile. Here, the model and the Street point the same way.

Market cap
$7.9B
Ticker Nerd rank
88 / 100
Median analyst target
$145
Analysts covering
16
Total return, dividends reinvested
1W
−0.1%
1M
+5.0%
YTD
+7.9%
1Y
+19.7%
From 52W high
−1.8%
From 52W low
+52.3%
$76
$118
52-week range, adjusted closes · the dot is the last close
Ticker Nerd rank

RYTM stock analysis: one number for the whole business

Consensus tells you what everyone already believes. The model scores Rhythm Pharmaceuticals, Inc. on its factor families — the same systematic rank behind the Ticker Nerd portfolio.

Where the model ranks itAs at 14 Aug 2026
88 / 100

Percentile across ~4,600 US stocks on Ticker Nerd’s systematic factor model. Higher is better. How the model is built and tested

Value
87
Revisions
84
Quality
80
Momentum
78
Issuance
78
Volatility
65
Accruals
55
Growth
47
Size
18

Value (87): The shares cost little relative to the profits and assets behind them — which can mean the market is too gloomy, or that the business really is in trouble.

Growth (47): Sales and profits are flat, shrinking, or growing more slowly than they were.

Size (18): Larger than most of the companies we track — more scrutinised, less often mispriced.

Built and run by Aslam Ghouse, an ex-Goldman Sachs quant trader with fourteen years in markets.

Wall Street

RYTM stock forecast 2026-2027: analyst price targets & predictions

The bullish and bearish analyst opinions on RYTM, reported as data — targets and ratings, the market's view beside the model's.

Share price and the analyst range, 12 monthsAdjusted close, US dollars
$80$100$120$140$160Oct 25Jan 26Apr 26Jul 26RYTMHigh $160Median $145Low $105

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

What Wall Street says16 analysts
15 Buy1 Hold0 Sell
Low $105Median $145High $160

The green dot is the last close — the median target sits +25.6% from it.

Recent analyst actionsNewest first

Of the 20 most recent actions, 5 moved their price target up and 0 moved it down.

DateFirmActionRatingTarget
7 Aug 2026JP MorganMaintainsOverweight$145$146
5 Aug 2026CitigroupMaintainsBuy$142$143
5 Aug 2026CitizensMaintainsMarket Outperform$155$160
5 Aug 2026RBC CapitalMaintainsOutperform$141$155
27 July 2026JP MorganInitiatesOverweight$145
27 July 2026JP MorganInitiatesOverweight
7 July 2026RBC CapitalMaintainsOutperform$137$141
7 July 2026RBC CapitalMaintainsOutperform
16 June 2026Canaccord GenuityMaintainsBuy
15 June 2026Wells FargoMaintainsOverweight
7 May 2026Canaccord GenuityMaintainsBuy
6 May 2026RBC CapitalMaintainsOutperform
6 May 2026Wells FargoMaintainsOverweight
23 Mar 2026HC Wainwright & Co.MaintainsBuy
20 Mar 2026B of A SecuritiesMaintainsBuy
20 Mar 2026CitigroupMaintainsBuy
20 Mar 2026CitizensMaintainsMarket Outperform
18 Mar 2026HC Wainwright & Co.MaintainsBuy
18 Mar 2026HC Wainwright& Co.MaintainsBuy
17 Mar 2026B of A SecuritiesMaintainsBuy

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Market Radar

This page is one stock. Monday covers all of them.

Computed off the Friday close and sent before the US open.

Market Radar reports the week’s largest rank changes across roughly 4,600 US stocks, the factor behind each one, and where the market went. RYTM appears on the weeks it earns a place.

Free, every Monday. Unsubscribe any time.

Estimates

RYTM analyst estimate revisions

Not the forecast itself — the direction analysts are revising it. Revision direction is one of the model's factor families.

Which way the estimates are movingNext fiscal year
Analysts raising
3
Analysts cutting
1
Fundamentals

Rhythm Pharmaceuticals, Inc. (RYTM) financial data

A margin means little on its own. Each bar marks where the figure sits across the whole US universe we score.

Valuation
Trailing P/E
−37.1×

Cheaper than 97% of US stocks

Price / sales
33.1×

Cheaper than 7% of US stocks

Price / book
77.2×

Cheaper than 2% of US stocks

EV / EBITDA
−39.3×

Cheaper than 92% of US stocks

Growth & margins
Revenue growth (YoY)
46.9%

Higher than 85% of US stocks

Earnings growth (YoY)
46.9%

Higher than 74% of US stocks

Gross margin
87.5%

Higher than 95% of US stocks

Operating margin
−68.1%

Higher than 15% of US stocks

Net margin
−85.6%

Higher than 7% of US stocks

Returns & dividend
Return on equity
−117.0%

Higher than 11% of US stocks

Return on assets
−31.0%

Higher than 14% of US stocks

Dividend yield

Bars mark the percentile across the ~4,600 US stocks Ticker Nerd covers, among those reporting the figure.

Peers

RYTM vs competitors

The nearest names by industry and size, scored by the same model — like for like.

Its peer group, ranked by the same modelBiotechnology
CompanyMarket capTKN rank
RYTMRhythm Pharmaceuticals, Inc.$7.9B
88
IBRXImmunityBio, Inc.$7.9B
48
TGTXTG Therapeutics, Inc.$7.7B
65
PCVXVaxcyte, Inc.$8.2B
49
IMVTImmunovant, Inc.$8.4B
40
ORKAOruka Therapeutics, Inc.$7.4B
41
CRNXCrinetics Pharmaceuticals, Inc.$8.7B
75

Look up any of the roughly 4,600 stocks we score.

The rank is the raw material. Whether the rules would actually own Rhythm Pharmaceuticals, Inc. — and when they’d sell — is the membership. See the Ticker Nerd 20 →

News

Latest RYTM news & analysis

Why Is Rhythm Pharmaceuticals Stock Trading Higher On Wednesday?

Benzinga · 12 Aug 2026positive

Shares of Rhythm Pharmaceuticals (RYTM) were trading higher on Wednesday, according to a Benzinga report.

Why it matters — A stock price increase on above-normal volume can signal shifting investor sentiment or market reaction to company developments.

Rhythm Pharmaceuticals Announces Participation in Upcoming Investor Conferences

GlobeNewsWire · 4 Aug 2026neutral

Rhythm Pharmaceuticals announced that CEO David Meeker, M.D., and CFO Hunter Smith will participate in fireside chats at three upcoming investor conferences.

Why it matters — Investor conference participation gives RYTM management a platform to communicate the company's strategy and pipeline progress to the investment community.

Rhythm Pharmaceuticals, Inc. (RYTM) Q2 2026 Earnings Call Transcript

Seeking Alpha · 4 Aug 2026neutral

Rhythm Pharmaceuticals held its Q2 2026 earnings call, with the transcript published by Seeking Alpha covering management's discussion of the quarter's results.

Why it matters — Earnings calls provide investors with management's perspective on operational performance and strategic direction for the quarter.

Rhythm Pharmaceuticals Q2 Earnings Call Highlights

MarketBeat · 4 Aug 2026positive

Rhythm Pharmaceuticals reported second-quarter 2026 global net product sales of $71.3 million for IMCIVREE, up 19% sequentially from $60.1 million in the first quarter. The company attributed the increase partly to an early positive reception of its U.S. launch in acquired hypothalamic obesity (HO).

Why it matters — A RYTM watcher would care because the sequential sales growth and early U.S. launch reception in HO signal momentum for IMCIVREE, the company's lead product.

Rhythm Pharmaceuticals, Inc. (RYTM) Reports Q2 Loss, Tops Revenue Estimates

Zacks Investment Research · 4 Aug 2026positive

Rhythm Pharmaceuticals reported a Q2 loss of $0.73 per share, narrower than the Zacks Consensus Estimate of a $0.81 loss and slightly better than the $0.75 per-share loss a year earlier, while also topping revenue estimates.

Why it matters — RYTM watchers would care because the company beat consensus expectations on both earnings and revenue for the quarter.

FAQ

Frequently asked questions about RYTM stock

What is the RYTM stock price forecast for 2026-2027?

The 16 Wall Street analysts covering Rhythm Pharmaceuticals, Inc. have a median 12-month price target of $145, with estimates ranging from $105 to $160. These are third-party analyst estimates, not Ticker Nerd forecasts, and they are frequently wrong.

Is RYTM stock a buy right now?

Of the 16 analysts covering Rhythm Pharmaceuticals, Inc., 15 rate it a Buy, 1 a Hold and 0 a Sell. Ticker Nerd's systematic factor model ranks Rhythm Pharmaceuticals, Inc. 88 out of 100 across roughly 4,600 US stocks as at 14 Aug 2026. None of this is personal advice — it does not consider your circumstances.

How does Ticker Nerd's model rank RYTM?

As at 14 Aug 2026, Rhythm Pharmaceuticals, Inc. ranks 88 out of 100 on Ticker Nerd's systematic factor model — a percentile across roughly 4,600 US stocks, built from its factor families. Its strongest factor family is Value (87 of 100).

Will RYTM stock go up?

No one can know that. What the data says: the median 12-month target from 16 analysts implies +25.6% from the last close, and Ticker Nerd's factor model ranks Rhythm Pharmaceuticals, Inc. 88 out of 100 as at 14 Aug 2026. Analyst targets are third-party estimates and frequently wrong; none of this is personal advice.

What is the RYTM stock forecast for 2030?

No analyst covering Rhythm Pharmaceuticals, Inc. publishes a 2030 price target — Wall Street targets run 12 to 18 months out. Sites quoting a 2030 price for RYTM are extrapolating price history, which says nothing about the business. The furthest attributed numbers are the current analyst targets: $105 to $160 over the next 12 months.

How has RYTM stock performed over the past year?

Rhythm Pharmaceuticals, Inc. returned +19.7% over the 12 months to 14 Aug 2026, with dividends reinvested. Past performance does not indicate future returns.

What does Rhythm Pharmaceuticals, Inc. do?

Rhythm Pharmaceuticals Inc. is a commercial-stage biopharmaceutical company focused on developing and commercializing therapies for rare neuroendocrine diseases, particularly those involving hyperphagia and severe obesity.

What is the latest news on RYTM?

The most recent item we track (Benzinga, 12 Aug 2026): "Why Is Rhythm Pharmaceuticals Stock Trading Higher On Wednesday?". Shares of Rhythm Pharmaceuticals (RYTM) were trading higher on Wednesday, according to a Benzinga report.

Company

About Rhythm Pharmaceuticals, Inc.

Rhythm Pharmaceuticals Inc. is a commercial-stage biopharmaceutical company focused on developing and commercializing therapies for rare neuroendocrine diseases, particularly those involving hyperphagia and severe obesity. Its lead product, IMCIVREE (setmelanotide), is a precision medicine targeting rare melanocortin-4 receptor (MC4R) diseases, such as POMC deficiency and Bardet-Biedl syndrome, where traditional weight-loss treatments often prove ineffective. The company addresses unmet needs in rare disease obesity, a niche insulated from broader market dynamics in weight management drugs. Rhythm Pharmaceuticals Inc. operates in the pharmaceuticals and biotech sector, emphasizing treatments for genetic disorders that cause uncontrollable hunger and related complications. Headquartered in Boston, Massachusetts, and founded in 2008, it serves patients through specialized healthcare channels, positioning itself as a leader in rare disease therapies within the neuroendocrine space.

CEO Dr. David P. Meeker M.D. · 414 employees · United States · https://rhythmtx.com