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ANVSANVSHealthcare · Biotechnology

ANVS Stock Forecast: Annovis Bio, Inc. Price Predictions for 2026-2027

Last close, 11 Sept 2026
$1.12
−5.88% on the day

The 4 Wall Street analysts covering Annovis Bio, Inc. hold a median 12-month price target of $9 — +703.6% from the last close. Ticker Nerd's systematic factor model, run across ~4,600 US stocks, ranks it 25 of 100 as at 11 Sept 2026 — in the lower half. The Street sees upside; the factor read is a caution. That gap is the story on this page.

Market cap
$47.7M
Ticker Nerd rank
25 / 100
Median analyst target
$9.00
Analysts covering
4
Revenue$0.0
Operating income−$14.4M
Net income−$14.8M
Free cash flow−$21.9M
Quarterly, 8 quarters to 30 June 2026 · latest quarter's figure shown
Total return, dividends reinvested
1W
−18.8%
1M
−40.7%
YTD
−67.6%
1Y
−53.1%
From 52W high
−78.0%
From 52W low
0.0%
$1.12
$5.10
52-week range, adjusted closes · the dot is the last close
Ticker Nerd rank

ANVS stock analysis: one number for the whole business

Consensus tells you what everyone already believes. The model scores Annovis Bio, Inc. on its factor families — the same systematic rank behind the Ticker Nerd portfolio.

Where the model ranks itAs at 11 Sept 2026
25 / 100

Percentile across ~4,600 US stocks on Ticker Nerd’s systematic factor model. Higher is better. How the model is built and tested

Size
82
Revisions
69
Accruals
66
Quality
29
Issuance
27
Growth
23
Value
18
Volatility
15
Momentum
12

Size (82): Smaller than most of the companies we track.

Momentum (12): The shares have been drifting down relative to others.

Built and run by Aslam Ghouse, an ex-Goldman Sachs quant trader with fourteen years in markets.

Wall Street

ANVS stock forecast 2026-2027: analyst price targets & predictions

The bullish and bearish analyst opinions on ANVS, reported as data — targets and ratings, the market's view beside the model's.

Share price and the analyst range, 12 monthsAdjusted close, US dollars
$0.00$5.00$10.00$15.00Oct 25Jan 26Apr 26Jul 26ANVSHigh $17.00Median $9.00Low $7.00

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Data provided by Twelve Data

What Wall Street says4 analysts
4 Buy0 Hold0 Sell
Low $7.00Median $9.00High $17.00

The green dot is the last close — the median target sits +703.6% from it.

Recent analyst actionsNewest first
DateFirmActionRatingTarget
28 Aug 2026Roth CapitalMaintainsBuy$8.00 → $7.00
18 Aug 2026Canaccord GenuityMaintainsBuy$17
18 Aug 2026Canaccord GenuityMaintainsBuy—
8 July 2026Roth CapitalInitiatesBuy$8.00
8 July 2026Roth CapitalInitiatesBuy—
14 Apr 2026Canaccord GenuityMaintainsBuy—
30 Sept 2025Canaccord GenuityMaintainsBuy—
3 Sept 2025HC Wainwright & Co.MaintainsBuy—
9 June 2025HC Wainwright & Co.MaintainsBuy—
15 May 2025Canaccord GenuityMaintainsBuy—
10 Feb 2025D. Boral CapitalDowngradeHold—
11 Nov 2024D. Boral CapitalMaintainsBuy—
11 Nov 2024HC Wainwright & Co.ReiteratesBuy—
25 Oct 2024Maxim GroupUpgradeBuy—
16 Oct 2024HC Wainwright & Co.ReiteratesBuy$30
15 Oct 2024EF HuttonMaintainsBuy$21
1 Oct 2024HC Wainwright & Co.ReiteratesBuy$30
15 Aug 2024EF HuttonMaintainsBuy—
15 Aug 2024HC Wainwright & Co.ReiteratesBuy—
13 Aug 2024EF HuttonInitiatesBuy—

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Market Radar

This page is one stock. Monday covers all of them.

Computed off the Friday close and sent before the US open.

Market Radar reports the week’s largest rank changes across roughly 4,600 US stocks, the factor behind each one, and where the market went. ANVS appears on the weeks it earns a place.

Free, every Monday. Unsubscribe any time.

Performance

ANVS vs the S&P 500

Both lines are total return — dividends reinvested — so the comparison is honest on both sides.

Over the twelve months to 11 Sept 2026, Annovis Bio, Inc. returned −53.1% against +17.5% for the S&P 500, dividends included.

ANVS vs S&P 500, last 12 monthsTotal return, rebased to 100
50100150200Oct 25Jan 26Apr 26Jul 26ANVSS&P 500

Download this chart as an image — free to reuse; link this page as the source.

Data provided by Twelve Data

Estimates

ANVS analyst estimate revisions

Not the forecast itself — the direction analysts are revising it. Revision direction is one of the model's factor families.

Which way the estimates are movingNext fiscal year
Analysts raising
0
Analysts cutting
1
Fundamentals

Annovis Bio, Inc. (ANVS) financial data

A margin means little on its own. Each bar marks where the figure sits across the whole US universe we score.

Valuation
Trailing P/E
−0.8×

Cheaper than 81% of US stocks

Price / sales
—
Price / book
−9.9×

Cheaper than 98% of US stocks

EV / EBITDA
−1.0×

Cheaper than 67% of US stocks

Growth & margins
Revenue growth (YoY)
—
Earnings growth (YoY)
—
Gross margin
—
Operating margin
0.0%

Higher than 32% of US stocks

Net margin
0.0%

Higher than 30% of US stocks

Returns & dividend
Return on equity
−703.7%

Higher than 2% of US stocks

Return on assets
−142.4%

Higher than 1% of US stocks

Dividend yield
—

Bars mark the percentile across the ~4,600 US stocks Ticker Nerd covers, among those reporting the figure.

Key statistics

Annovis Bio, Inc. (ANVS) statistics: revenue, profit & scale

The headline figures, each with its date. Every row carries its own link — cite it straight from here.

  • Annovis Bio, Inc. has a market value of $47.7M and an enterprise value of $29.0M.

  • Revenue in the twelve months to 30 June 2026: $0.0.

  • Net income over the same four quarters: −$49.5M.

  • Free cash flow in the twelve months to 30 June 2026: −$43.3M.

  • Shares outstanding: 42.6M.

  • Trailing P/E: −0.8×; forward P/E: −1.3× — the forward figure prices analyst consensus estimates, not reported earnings.

  • Annovis Bio, Inc. employs 7 people.

Statement figures: company filings via Twelve Data, four quarters to 30 June 2026 · market figures as at 13 Sept 2026

Data provided by Twelve Data

Peers

ANVS vs competitors

The nearest names by industry and size, scored by the same model — like for like.

Its peer group, ranked by the same modelBiotechnology
CompanyMarket capTKN rank
ANVSAnnovis Bio, Inc.$47.7M
25
HOWLWerewolf Therapeutics, Inc.$47.7M
80
MCRBSeres Therapeutics, Inc.$48.0M
49
TVGNTevogen, Inc.$47.2M
15
IBOImpact BioMedical, Inc.$48.1M
23
TILInstil Bio, Inc.$50.1M
36
ATNMActinium Pharmaceuticals, Inc.$43.9M
73

Look up any of the roughly 4,600 stocks we score.

The rank is the raw material. Whether the rules would actually own Annovis Bio, Inc. — and when they’d sell — is the membership. See the Ticker Nerd 20 →

News

Latest ANVS news & analysis

Annovis Bio (ANVS) Loses 26.5% in 4 Weeks, Here's Why a Trend Reversal May be Around the Corner

Zacks Investment Research · 8 Sept 2026positive

Annovis Bio (ANVS) has fallen 26.5% over the past four weeks and is now technically oversold, suggesting heavy selling pressure has been exhausted. Strong agreement among Wall Street analysts in revising earnings estimates higher indicates a potential trend reversal for the stock in the near term.

Why it matters — A shareholder would care because an oversold condition combined with upward analyst estimate revisions points to a possible near-term reversal in the stock's direction.

Annovis Bio Targets March 2027 Alzheimer's Readout, Prepares Rolling NDA

MarketBeat · 3 Sept 2026neutral

Annovis Bio stated it expects to report top-line results from the six-month portion of its pivotal Phase III Alzheimer's disease trial in March 2027. The company is also preparing a rolling new drug application (NDA), which management said could begin in May if the study meets its efficacy requirements.

Why it matters — ANVS watchers will track these milestones as the March 2027 readout and a potential May rolling NDA submission are key regulatory and clinical steps for the company's Alzheimer's candidate.

Annovis to Host Corporate Update Webinar on September 2, 2026

GlobeNewsWire · 25 Aug 2026neutral

Annovis Bio announced it will host a corporate update webinar followed by a live Q&A session on September 2, 2026. The company is a Phase 3 clinical-stage biotechnology firm developing the oral therapy buntanetap for Alzheimer's and Parkinson's disease.

Why it matters — ANVS watchers would care because the webinar may offer an update on the company's ongoing clinical development program for buntanetap.

Annovis Provides Corporate Updates and Second Quarter 2026 Financial Results

GlobeNewsWire · 14 Aug 2026neutral

Annovis Bio, Inc. provided business updates and reported financial results for the second quarter ended June 30, 2026. The Phase 3 clinical-stage biotechnology company is developing the oral investigational therapy buntanetap for neurodegenerative diseases such as Alzheimer's and Parkinson's disease.

Why it matters — The release updates ANVS watchers on the company's latest operational progress and Q2 2026 financial performance.

FAQ

Frequently asked questions about ANVS stock

What is the ANVS stock price forecast for 2026-2027?

The 4 Wall Street analysts covering Annovis Bio, Inc. have a median 12-month price target of $9, with estimates ranging from $7 to $17. These are third-party analyst estimates, not Ticker Nerd forecasts, and they are frequently wrong.

Is ANVS stock a buy right now?

Of the 4 analysts covering Annovis Bio, Inc., 4 rate it a Buy, 0 a Hold and 0 a Sell. Ticker Nerd's systematic factor model ranks Annovis Bio, Inc. 25 out of 100 across roughly 4,600 US stocks as at 11 Sept 2026. None of this is personal advice — it does not consider your circumstances.

How does Ticker Nerd's model rank ANVS?

As at 11 Sept 2026, Annovis Bio, Inc. ranks 25 out of 100 on Ticker Nerd's systematic factor model — a percentile across roughly 4,600 US stocks, built from its factor families. Its strongest factor family is Size (82 of 100).

Will ANVS stock go up?

No one can know that. What the data says: the median 12-month target from 4 analysts implies +703.6% from the last close, and Ticker Nerd's factor model ranks Annovis Bio, Inc. 25 out of 100 as at 11 Sept 2026. Analyst targets are third-party estimates and frequently wrong; none of this is personal advice.

What is the ANVS stock forecast for 2030?

No analyst covering Annovis Bio, Inc. publishes a 2030 price target — Wall Street targets run 12 to 18 months out. Sites quoting a 2030 price for ANVS are extrapolating price history, which says nothing about the business. The furthest attributed numbers are the current analyst targets: $7 to $17 over the next 12 months.

How has ANVS stock performed over the past year?

Annovis Bio, Inc. returned -53.1% over the 12 months to 11 Sept 2026, with dividends reinvested. Past performance does not indicate future returns.

What does Annovis Bio, Inc. do?

Annovis Bio, Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for neurodegenerative diseases.

What is the latest news on ANVS?

The most recent item we track (Zacks Investment Research, 8 Sept 2026): "Annovis Bio (ANVS) Loses 26.5% in 4 Weeks, Here's Why a Trend Reversal May be Around the Corner". Annovis Bio (ANVS) has fallen 26.5% over the past four weeks and is now technically oversold, suggesting heavy selling pressure has been exhausted. Strong agreement among Wall Street analysts in revising earnings estimates higher indicates a potential trend reversal for the stock in the near term.

Company

About Annovis Bio, Inc.

Annovis Bio, Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for neurodegenerative diseases. Its current pipeline centers on oral small-molecule candidates designed to address disorders such as Alzheimer’s disease and Parkinson’s disease, with additional programs targeting traumatic brain injury, stroke, Lewy body dementia, and advanced Alzheimer’s disease. The company’s lead candidate, buntanetap, is being studied for chronic neurodegeneration, while ANVS405 and ANVS301 extend its research into acute and later-stage neurological conditions. Annovis Bio’s work is directed at central nervous system disorders where protein misfolding, neuroinflammation, and cognitive decline play key roles. Based in Malvern, Pennsylvania, Annovis Bio operates as a research-driven drug development company within the biotechnology sector.

CEO Dr. Maria L. Maccecchini Ph.D. · 7 employees · United States · https://www.annovisbio.com