Corbus Pharmaceuticals Announces First Patient Dosed in TEMPO-1 Registrational Study of CRB-701 in Patients with 2L+ Oropharyngeal Cancer
Corbus Pharmaceuticals announced that the first patient has been dosed in its TEMPO-1 registrational study of CRB-701, a next-generation Nectin-4 targeted antibody drug conjugate, in second-line and beyond oropharyngeal squamous cell carcinoma. The company noted that OPSCC incidence and prevalence are rising in the U.S., largely driven by HPV infection, with an estimated 14,000 patients eligible for treatment annually.
Why it matters — This milestone advances CRB-701 into a registrational study targeting a growing patient population in oropharyngeal cancer, a key clinical development step for CRBP's pipeline.