OS Therapies Achieves Statistically Significant Benefit for OST-HER2-Treated Patients in Interim 3-Year Overall Survival Analysis of Phase 2b Pulmonary Metastatic Osteosarcoma Trial
OS Therapies reported interim 3-year overall survival data from its Phase 2b pulmonary metastatic osteosarcoma trial, showing a 71.2% 3-year overall survival rate for OST-HER2-treated patients versus a 45.8% comparable combined historical control (p = 0.002). The company also received $3.15 million in VAT refunds into OS Therapies UK, Ltd., and noted that two remaining patients have monitoring visits scheduled for September and early October 2026.
Why it matters — OSTX watchers would care because the statistically significant overall survival improvement versus historical controls suggests the investigational treatment is performing favorably in a hard-to-treat metastatic osteosarcoma setting, with further trial data expected in 2026.