Eloxx Pharmaceuticals Announces First Patients Dosed in Phase 2b EXACT Study of Exaluren in Nonsense Mutation Alport Syndrome
Eloxx Pharmaceuticals announced that the first two patients have been dosed in the EXACT Study, a Phase 2b clinical trial of exaluren for nonsense mutation Alport syndrome. Topline data from the 16-week placebo-controlled portion are expected mid-2027, with a final readout expected by the end of 2027.
Why it matters — A watcher would care because dosing initiation moves the company's lead kidney-disease candidate forward in clinical development and establishes a timeline for key data readouts.