Monte Rosa Therapeutics Announces Milestone Achievement Associated with Initiation of Phase 2 Clinical Study for VAV1-directed Molecular Glue Degrader MRT-6160 (DDY391)
Monte Rosa Therapeutics announced that its collaborator Novartis has initiated a Phase 2 clinical study for the VAV1-directed molecular glue degrader MRT-6160 (DDY391) in participants with Sjögren's disease. This is a milestone under their global exclusive development and commercialization license agreement, triggering a milestone payment to Monte Rosa based on the first patient visit, with additional Phase 2 study initiation milestones possible.
Why it matters — The Phase 2 study initiation by Novartis triggers a milestone payment to Monte Rosa and marks progress for its lead MGD candidate MRT-6160 across immune-mediated diseases.