Rigel Announces Availability of VEPPANU™ (vepdegestrant) for Patients with ER+/HER2-, ESR1-Mutated Advanced or Metastatic Breast Cancer
Rigel Pharmaceuticals announced that VEPPANU (vepdegestrant) is now available by prescription in the U.S. for adults with ER+/HER2-, ESR1-mutated advanced or metastatic breast cancer whose disease progressed after at least one line of endocrine therapy. The drug is described as the first and only FDA-approved PROTAC.
Why it matters — This marks the commercial availability of Rigel's first-and-only FDA-approved PROTAC for a defined breast cancer patient population, expanding the company's product portfolio.