KRYSKRYSHealthcare · Biotechnology

KRYS Stock Forecast: Krystal Biotech, Inc. Price Predictions for 2026-2027

Last close, 3 Aug 2026
$313
−8.37% on the day

The 10 Wall Street analysts covering Krystal Biotech, Inc. hold a median 12-month price target of $387 — +23.7% from the last close. Ticker Nerd's systematic factor model, run across ~4,600 US stocks, ranks it 73 of 100 as at 1 Aug 2026 — in the upper half. Here, the model and the Street point the same way.

Market cap
$10.1B
Ticker Nerd rank
73 / 100
Median analyst target
$387
Analysts covering
10
Total return, dividends reinvested
1W
−11.2%
1M
−16.7%
YTD
+26.8%
1Y
+99.1%
From 52W high
−17.3%
From 52W low
+131.6%
$135
$378
52-week range, adjusted closes · the dot is the last close
Ticker Nerd rank

KRYS stock analysis: one number for the whole business

Consensus tells you what everyone already believes. The model scores Krystal Biotech, Inc. on its factor families — the same systematic rank behind the Ticker Nerd portfolio.

Where the model ranks itAs at 1 Aug 2026
73 / 100

Percentile across ~4,600 US stocks on Ticker Nerd’s systematic factor model. Higher is better. How the model is built and tested

Value
94
Volatility
92
Momentum
89
Quality
89
Growth
59
Issuance
52
Revisions
45
Accruals
30
Size
16

Value (94): The shares cost little relative to the profits and assets behind them — which can mean the market is too gloomy, or that the business really is in trouble.

Accruals (30): A large share of reported profit has not shown up as cash, or the balance sheet is expanding quickly — both tend to unwind.

Size (16): Larger than most of the companies we track — more scrutinised, less often mispriced.

The rank is the raw material. Whether the rules would actually own Krystal Biotech, Inc. — and when they’d sell — is the membership.

Wall Street

KRYS stock forecast 2026-2027: analyst price targets & predictions

The bullish and bearish analyst opinions on KRYS, reported as data — targets and ratings, the market's view beside the model's.

Share price and the analyst range, 12 monthsAdjusted close, US dollars
$100$200$300$400$500Oct 25Jan 26Apr 26Jul 26KRYSHigh $474Median $387Low $284

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

What Wall Street says10 analysts
9 Buy1 Hold0 Sell
Low $284Median $387High $474

The green dot is the last close — the median target sits +23.7% from it.

Recent analyst actionsNewest first
DateFirmActionRatingTarget
14 July 2026B of A SecuritiesMaintainsBuy$364$396
18 June 2026TD CowenMaintainsBuy
16 June 2026HC Wainwright & Co.MaintainsBuy
1 June 2026HC Wainwright & Co.ReiteratesBuy
22 May 2026HC Wainwright & Co.ReiteratesBuy
18 May 2026HC Wainwright & Co.ReiteratesBuy
5 May 2026CitigroupMaintainsBuy
5 May 2026Evercore ISI GroupMaintainsOutperform
4 May 2026HC Wainwright & Co.ReiteratesBuy
27 Mar 2026Wolfe ResearchInitiatesPeer Perform
25 Feb 2026GuggenheimMaintainsBuy
18 Feb 2026Chardan CapitalMaintainsBuy
18 Feb 2026CitigroupMaintainsBuy
17 Feb 2026JefferiesMaintainsBuy
2 Feb 2026Goldman SachsMaintainsBuy
22 Jan 2026B of A SecuritiesMaintainsBuy
12 Jan 2026CitigroupMaintainsBuy
9 Jan 2026CitigroupMaintainsBuy
9 Jan 2026HC Wainwright & Co.ReiteratesBuy
9 Jan 2026TD CowenMaintainsBuy

Price targets and ratings are third-party analyst estimates, reported here as data. They are not Ticker Nerd forecasts, and they are frequently wrong.

Estimates

KRYS analyst estimate revisions

Not the forecast itself — the direction analysts are revising it. Revision direction is one of the model's factor families.

Which way the estimates are movingNext fiscal year
EPS revision, 90 days
+8.3%
Analysts raising
0
Analysts cutting
1
Fundamentals

Krystal Biotech, Inc. (KRYS) financial data

A margin means little on its own. Each bar marks where the figure sits across the whole US universe we score.

Valuation
Trailing P/E
45.7×

Cheaper than 17% of US stocks

Price / sales
24.1×

Cheaper than 8% of US stocks

Price / book
7.9×

Cheaper than 13% of US stocks

EV / EBITDA
51.2×

Cheaper than 5% of US stocks

Growth & margins
Revenue growth (YoY)
31.9%

Higher than 81% of US stocks

Earnings growth (YoY)
56.5%

Higher than 79% of US stocks

Gross margin
94.6%

Higher than 98% of US stocks

Operating margin
46.1%

Higher than 95% of US stocks

Net margin
53.9%

Higher than 96% of US stocks

Returns & dividend
Return on equity
19.9%

Higher than 82% of US stocks

Return on assets
9.0%

Higher than 91% of US stocks

Dividend yield

Bars mark the percentile across the ~4,600 US stocks Ticker Nerd covers, among those reporting the figure.

Peers

KRYS vs competitors

The nearest names by industry and size, scored by the same model — like for like.

Its peer group, ranked by the same modelBiotechnology
CompanyMarket capTKN rank
KRYSKrystal Biotech, Inc.$10.1B
73
APGEApogee Therapeutics, Inc.$10.1B
45
HALOHalozyme Therapeutics, Inc.$9.8B
85
NUVLNuvalent, Inc.$9.7B
SMMTSummit Therapeutics, Inc.$10.4B
18
CYTKCytokinetics, Inc.$9.6B
74
MDGLMadrigal Pharmaceuticals, Inc.$10.7B
67
Market Radar

This page is one stock. Monday covers all of them.

Computed off the Friday close and sent before the US open.

Market Radar reports the week’s largest rank changes across roughly 4,600 US stocks, the factor behind each one, and where the market went. KRYS appears on the weeks it earns a place.

Free, every Monday. Unsubscribe any time.

News

Latest KRYS news & analysis

Krystal Biotech, Inc. (KRYS) Q2 2026 Earnings Call Transcript

Seeking Alpha · 3 Aug 2026neutral

Krystal Biotech, Inc. published its Q2 2026 earnings call transcript. The transcript covers the company's quarterly financial and business discussion.

Why it matters — A KRYS watcher would review the transcript for management's commentary on the company's quarterly performance.

Read Between These Lines As Eli Lilly, Hot IPO And More Face Key Test

Investors Business Daily · 3 Aug 2026neutral

Investors Business Daily reports that stocks including Eli Lilly, Twilio, and Hinge Health face a key test as they move ahead of earnings reports, advising investors to pay attention to important chart lines. Krystal Biotech (KRYS) is not mentioned in this item.

Why it matters — KRYS is not referenced in this item, so it offers no direct news about the company for Krystal Biotech watchers.

Krystal Biotech Q2 Earnings Call Highlights

MarketBeat · 3 Aug 2026positive

Krystal Biotech reported second-quarter 2026 net revenue of $119.2 million from global sales of VYJUVEK, up 24% from $96 million in the prior-year period. The increase came as the company expanded treatment access for patients with dystrophic epidermolysis bullosa (DEB) in the United States and overseas.

Why it matters — The 24% year-over-year revenue growth and expanding DEB treatment access indicate continued commercial traction for Krystal Biotech’s VYJUVEK.

Krystal Biotech, Inc. (KRYS) Q2 Earnings and Revenues Beat Estimates

Zacks Investment Research · 3 Aug 2026positive

Krystal Biotech reported Q2 earnings of $1.79 per share, surpassing the Zacks Consensus Estimate of $1.70 per share and up from $1.29 per share in the same quarter last year.

Why it matters — The earnings beat and year-over-year growth signal continued financial outperformance, which KRYS watchers may view as a sign of strong operational execution.

Krystal Biotech Announces Second Quarter 2026 Financial and Operating Results

GlobeNewsWire · 3 Aug 2026positive

Krystal Biotech reported second-quarter 2026 financial results, including $119.2 million in global VYJUVEK revenue for the quarter and $965.9 million since launch, ending with $1.1 billion in cash and investments. The company also noted it remains on track for VYJUVEK launches in Spain and Italy and expects multiple clinical data readouts in the second half of 2026.

Why it matters — KRYS watchers would follow this update because VYJUVEK revenue trends, upcoming European launches, and near-term pipeline catalysts could signal the company's commercial and clinical momentum.

FAQ

Frequently asked questions about KRYS stock

What is the KRYS stock price forecast for 2026-2027?

The 10 Wall Street analysts covering Krystal Biotech, Inc. have a median 12-month price target of $387, with estimates ranging from $284 to $474. These are third-party analyst estimates, not Ticker Nerd forecasts, and they are frequently wrong.

Is KRYS stock a buy right now?

Of the 10 analysts covering Krystal Biotech, Inc., 9 rate it a Buy, 1 a Hold and 0 a Sell. Ticker Nerd's systematic factor model ranks Krystal Biotech, Inc. 73 out of 100 across roughly 4,600 US stocks as at 1 Aug 2026. None of this is personal advice — it does not consider your circumstances.

How does Ticker Nerd's model rank KRYS?

As at 1 Aug 2026, Krystal Biotech, Inc. ranks 73 out of 100 on Ticker Nerd's systematic factor model — a percentile across roughly 4,600 US stocks, built from its factor families. Its strongest factor family is Value (94 of 100).

Will KRYS stock go up?

No one can know that. What the data says: the median 12-month target from 10 analysts implies +23.7% from the last close, and Ticker Nerd's factor model ranks Krystal Biotech, Inc. 73 out of 100 as at 1 Aug 2026. Analyst targets are third-party estimates and frequently wrong; none of this is personal advice.

What is the KRYS stock forecast for 2030?

No analyst covering Krystal Biotech, Inc. publishes a 2030 price target — Wall Street targets run 12 to 18 months out. Sites quoting a 2030 price for KRYS are extrapolating price history, which says nothing about the business. The furthest attributed numbers are the current analyst targets: $284 to $474 over the next 12 months.

How has KRYS stock performed over the past year?

Krystal Biotech, Inc. returned +99.1% over the 12 months to 3 Aug 2026, with dividends reinvested. Past performance does not indicate future returns.

What does Krystal Biotech, Inc. do?

Krystal Biotech Inc. is a commercial-stage biotechnology company focused on developing and commercializing genetic medicines for severe, life-threatening, and rare diseases with high unmet medical needs.

What is the latest news on KRYS?

The most recent item we track (Seeking Alpha, 3 Aug 2026): "Krystal Biotech, Inc. (KRYS) Q2 2026 Earnings Call Transcript". Krystal Biotech, Inc. published its Q2 2026 earnings call transcript. The transcript covers the company's quarterly financial and business discussion.

Company

About Krystal Biotech, Inc.

Krystal Biotech Inc. is a commercial-stage biotechnology company focused on developing and commercializing genetic medicines for severe, life-threatening, and rare diseases with high unmet medical needs. The company specializes in redosable gene therapies built on a proprietary herpes simplex virus type 1 (HSV-1) vector platform, enabling targeted delivery of therapeutic genes to skin and other tissues. Krystal Biotech’s core area of impact is specialty dermatology, where it offers Vyjuvek, a prescription gene therapy for dystrophic epidermolysis bullosa, a rare inherited skin disorder characterized by extreme fragility and chronic wounds. Beyond dermatology, the company is advancing a pipeline that extends its platform into oncology and respiratory indications, aiming to address complex solid tumors and genetic lung diseases through localized gene delivery. Krystal Biotech operates as a fully integrated enterprise, with in-house CGMP manufacturing facilities to support discovery, clinical development, and commercial supply of its therapies. Founded in 2016 and headquartered in Pittsburgh, Pennsylvania, Krystal Biotech plays a distinct role in the biotechnology market as a leader in redosable gene therapy for rare conditions.

CEO Mr. Krish S. Krishnan M.B.A., M.S. · 295 employees · United States · https://www.krystalbio.com