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SYRE Stock Forecast: Spyre Therapeutics Inc. Price Predictions for 2025

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$18.16

-0.86 (-4.52%)

SYRE Stock Forecast 2025-2026

$18.16
Current Price
$1.09B
Market Cap
11 Ratings
Buy 10
Hold 1
Sell 0
Wall St Analyst Ratings

Distance to SYRE Price Targets

+291.0%
To High Target of $71.00
+257.9%
To Median Target of $65.00
+48.7%
To Low Target of $27.00

SYRE Price Momentum

-1.3%
1 Week Change
-4.4%
1 Month Change
-51.7%
1 Year Change
-22.0%
Year-to-Date Change
-57.8%
From 52W High of $43.00
+5.3%
From 52W Low of $17.24
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Latest SYRE Stock Price Targets & Analyst Predictions

Based on our analysis of 11 Wall Street analysts, SYRE has a bullish consensus with a median price target of $65.00 (ranging from $27.00 to $71.00). The overall analyst rating is Strong Buy (9.6/10). Currently trading at $18.16, the median forecast implies a 257.9% upside. This outlook is supported by 10 Buy, 1 Hold, and 0 Sell ratings.

Conversely, the most conservative target is provided by Alex Thompson at Stifel, suggesting a 48.7% upside.

Please note that analyst price targets are forward-looking estimates subject to substantial market, economic, and company-specific risks. Past performance does not guarantee future results, and actual stock performance may materially differ from these projections. Investors should conduct their own due diligence and consider their investment objectives and risk tolerance before making investment decisions.

SYRE Analyst Ratings

10
Buy
1
Hold
0
Sell

SYRE Price Target Range

Low
$27.00
Average
$65.00
High
$71.00
Current: $18.16

Latest SYRE Stock Forecasts by Analyst

These are the latest 20 analyst ratings and price targets for SYRE.

Date Firm Analyst Rating Change Price Target
Dec 11, 2024 Jones Trading Debanjana Chatterjee Hold Initiates $0.00
Nov 13, 2024 Baird Colleen Kusy Outperform Maintains $65.00
Oct 25, 2024 Guggenheim Yatin Suneja Buy Maintains $65.00
Sep 4, 2024 Wedbush David Nierengarten Outperform Initiates $45.00
Jul 16, 2024 Evercore ISI Group Umer Raffat Outperform Initiates $0.00
May 13, 2024 Wells Fargo Yanan Zhu Overweight Maintains $40.00
May 10, 2024 BTIG Julian Harrison Buy Maintains $40.00
May 2, 2024 Baird Colleen Kusy Outperform Initiates $50.00
Mar 26, 2024 Stifel Alex Thompson Buy Reiterates $54.00
Mar 1, 2024 Wells Fargo Yanan Zhu Overweight Upgrade $35.00
Dec 20, 2023 BTIG Julian Harrison Buy Initiates $32.00
Dec 18, 2023 Stifel Alex Thompson Buy Maintains $27.00
Dec 11, 2023 Jefferies Akash Tewari Buy Initiates $31.00
Dec 11, 2023 Guggenheim Buy Initiates $44.00
Nov 29, 2023 TD Cowen Tyler Van Buren Outperform Initiates $0.00

Spyre Therapeutics Inc. (SYRE) Competitors

The following stocks are similar to Spyre based on their market capitalization and industry sector. These similar stocks potentially provide investors with alternative investment opportunities within the same market segment.

Spyre Therapeutics Inc. (SYRE) Financial Data

Spyre Therapeutics Inc. has a market capitalization of $1.09B with a P/E ratio of 1.7x. The company generates $0 in trailing twelve-month revenue with a 0.0% profit margin.

Revenue growth is N/A quarter-over-quarter, while maintaining an operating margin of 0.0% and return on equity of -59.3%.

Valuation Metrics

Market Cap $1.09B
Enterprise Value $647.34M
P/E Ratio 1.7x
PEG Ratio -4.4x
Price/Sales 0.0x

Growth & Margins

Revenue Growth (YoY) N/A
Gross Margin N/A
Operating Margin 0.0%
Net Margin 0.0%
EPS Growth N/A

Financial Health

Cash/Price Ratio +55.1%
Current Ratio 11.3x
Debt/Equity 0.0x
ROE -59.3%
ROA -27.4%
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Spyre Therapeutics Inc. logo

Spyre Therapeutics Inc. (SYRE) Business Model

About Spyre Therapeutics Inc.

What They Do

Develops therapies for autoimmune and inflammatory diseases.

Business Model

Spyre Therapeutics generates revenue through the research and development of innovative biopharmaceutical therapies. By focusing on drug discovery, the company aims to bring novel medicines to market, addressing the root causes of autoimmune and inflammatory disorders.

Additional Information

The company operates within the biotechnology sector and has a diverse pipeline of biologic and small molecule drugs. Spyre Therapeutics is positioned as a potential growth driver in the biotech industry, appealing to investors interested in impactful healthcare solutions and advancements in treating unmet medical needs.

Company Information

Sector

Healthcare

Industry

Biotechnology

Employees

65

CEO

Dr. Cameron Turtle DPHIL, Ph.D.

Country

United States

IPO Year

2016

Spyre Therapeutics Inc. (SYRE) Latest News & Analysis

SYRE stock latest news image
Quick Summary

Spyre Therapeutics approved stock options for 132,200 shares to five non-executive employees as equity inducement awards under its 2018 Equity Inducement Plan.

Why It Matters

The granting of stock options to employees can indicate confidence in the companyโ€™s future, potentially boosting morale and aligning employee interests with shareholders, which may influence stock performance.

Source: PRNewsWire
Market Sentiment: Neutral
SYRE stock latest news image
Quick Summary

Spyre Therapeutics focuses on monoclonal antibodies for inflammatory bowel disease, has $603.1 million in cash, and aims for improved efficacy in ulcerative colitis with combination therapies.

Why It Matters

Spyre Therapeutics' strong cash position and innovative therapies in inflammatory bowel disease could lead to significant market opportunities, enhancing its valuation and growth potential.

Source: Seeking Alpha
Market Sentiment: Positive
SYRE stock latest news image
Quick Summary

Spyre Therapeutics reported positive Phase 1 trial data for SPY001 and raised $230 million in a public offering. Phase 2 trials for SPY001, SPY002, and SPY003 are set for mid-2025, with cash reserves of $603 million.

Why It Matters

Positive trial results and a strong balance sheet position Spyre Therapeutics for potential growth. Upcoming milestones in drug development could drive stock performance and investor interest.

Source: PRNewsWire
Market Sentiment: Neutral
SYRE stock latest news image
Quick Summary

Spyre Therapeutics (NASDAQ: SYRE) will participate in the TD Cowen Healthcare Conference on March 4 and the Jefferies Biotech Summit on March 11, 2025, offering investor meetings and webcasts.

Why It Matters

Spyre Therapeutics' participation in major investor conferences signals potential interest and visibility in the biotech sector, possibly impacting investor sentiment and stock performance.

Source: PRNewsWire
Market Sentiment: Neutral
SYRE stock latest news image
Quick Summary

Spyre Therapeutics (NASDAQ: SYRE) presented at the ECCO Congress on the efficacy of combined ฮฑ4ฮฒ7 integrin and TL1A cytokine inhibition for treating IBD, showing superior results in mouse models.

Why It Matters

Spyre Therapeutics' positive data on its dual therapy for IBD could enhance its market position and attract investor interest, potentially boosting stock value and future funding opportunities.

Source: PRNewsWire
Market Sentiment: Neutral
SYRE stock latest news image
Quick Summary

Spyre Therapeutics (SYRE) has a consensus price target indicating a 158.9% upside. Upward revisions in earnings estimates may suggest potential short-term gains.

Why It Matters

A 158.9% upside potential suggests significant growth for Spyre Therapeutics (SYRE), while rising earnings estimates indicate positive momentum, potentially driving stock prices higher.

Source: Zacks Investment Research
Market Sentiment: Positive

Frequently Asked Questions About SYRE Stock

What is Spyre Therapeutics Inc.'s (SYRE) stock forecast for 2025?

Based on our analysis of 11 Wall Street analysts, Spyre Therapeutics Inc. (SYRE) has a median price target of $65.00. The highest price target is $71.00 and the lowest is $27.00.

Is SYRE stock a good investment in 2025?

According to current analyst ratings, SYRE has 10 Buy ratings, 1 Hold ratings, and 0 Sell ratings. The stock is currently trading at $18.16. Always conduct your own research and consider your investment goals before making investment decisions.

What is the long-term price prediction for SYRE stock?

Wall Street analysts predict SYRE stock could reach $65.00 in the next 12 months. This represents a 257.9% increase from the current price of $18.16. Please note that this is a projection by Wall Street analysts and not a guarantee.

What is Spyre Therapeutics Inc.'s business model?

Spyre Therapeutics generates revenue through the research and development of innovative biopharmaceutical therapies. By focusing on drug discovery, the company aims to bring novel medicines to market, addressing the root causes of autoimmune and inflammatory disorders.

What is the highest forecasted price for SYRE Spyre Therapeutics Inc.?

The highest price target for SYRE is $71.00 from at , which represents a 291.0% increase from the current price of $18.16.

What is the lowest forecasted price for SYRE Spyre Therapeutics Inc.?

The lowest price target for SYRE is $27.00 from Alex Thompson at Stifel, which represents a 48.7% increase from the current price of $18.16.

What is the overall SYRE consensus from analysts for Spyre Therapeutics Inc.?

The overall analyst consensus for SYRE is bullish. Out of 11 Wall Street analysts, 10 rate it as Buy, 1 as Hold, and 0 as Sell, with a median price target of $65.00.

How accurate are SYRE stock price projections?

Stock price projections, including those for Spyre Therapeutics Inc., are based on various factors including financial models, market conditions, and analyst forecasts. While these predictions provide valuable insights, they should be considered alongside your own research and risk tolerance.

Important Disclaimer

The information provided by Ticker Nerd is for educational and informational purposes only. It should not be considered financial or investment advice. Past performance is not indicative of future results. Always conduct your own research and consult with a qualified financial advisor before making any investment decisions. Analyst ratings and price forecasts are sourced from Wall St analysts and other experts. These projections are speculative and do not guarantee future stock performance.

Last updated: March 26, 2025 2:52 PM UTC